@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3061: (2016-02-13 )
MSAHKDFTLAPRASGSVSWVETLVISALALGLGWWFSPDDPLQVNATFPWVILAPLLLGMRYGFVRGLASAALLVAALFAFRARGVEAYAQVPAAFIVGVLLCAMLVGEFRDIWERRLERLELANEYRQLRLDEFTRAHHILRISHDRLEQRVAGNDQSLRSSLLGLRQLLRELPGDEAPLDALAETVLALLAQYGSLRIAGLYRVRYDRTPEPQPLATLGEMPALDADDLLVRTCLERGELVSVRQELLERGEQRAHSALQVCVPLVDTDGRILALLAVEQMPFFVFNERTFSLLAILAGHIADLLQSDRRALQLADIDAQRFSQYLKRSLLDARDHGLPACLYAFELTDARYGEEVQRLLEGSQRGLDVQLRLRNDEGRRVLLVLLPLTSAEGSQGYLQRLRILFAERFGQARELESLGVRIRQYELDAGNDRQALGHFLFNECGLNDQQVAI
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170....-...180.......190....----.-----..200.......210.---.....-.220-----.---------.--.------------......-----230.......240.......250-----.----...--...260.......270.......280..-.-....290.......300.......---310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSAHK
D
F
T
LAPRASG
S
V
S
W
V
E
T
L
V
I
S
A
L
A
L
G
L
GWWFSPDD
P
L
Q
VNAT
F
P
W
V
I
L
A
P
L
L
L
G
M
R
Y
G
F
V
R
G
L
A
S
A
A
L
L
V
A
A
L
F
A
F
R
AR
G
V
E
A
Y
A
QV
P
A
A
F
I
V
G
V
L
L
C
A
M
L
V
G
E
F
R
D
I
W
E
R
R
L
E
R
L
E
L
A
N
E
Y
R
Q
L
R
L
D
E
F
T
RA
H
H
I
L
R
I
S
H
D
R
L
E
Q
R
VAGN
D
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
ELPG-DEA
P
L
D
A
L
A
E
T
V
L
A
L
L
A
QYG----S-----
L
R
I
A
G
L
Y
R
V
RYDRTPE---PQ
P
L
A
-TL-------G---------E--M------------PAL
D
A
D
-----
D
L
L
V
R
T
C
LERG
E
L
V
S
V
R
Q
E
L
L
E
R
-----
G
----
E
Q
R
--
A
H
S
A
L
Q
V
C
V
P
LVDTDG
R
I
L
A
L
L
A
VEQM
P
-
F
-
F
V
FNE
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
S---
D
R
R
A
L
Q
L
ADI
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
DARDHG
L
P
A
C
L
Y
A
F
ELTDAR
Y
G
E
E
V
Q
R
L
L
EGSQRG
L
D
V
Q
L
R
L
RNDEG
R
R
V
L
L
V
L
L
PLTSAEG
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
RFGQ
A
R
E
L
E
S
LG
V
R
I
R
Q
Y
ELDAGN
D
R
Q
A
L
G
H
F
L
F
N
ECGLNDQQVAI
1
PsiBlast_PDB
96.13
100%
-142
- C5 -
4ETX
-
?
A:
[155-454]
----------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
D
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
Y
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
A
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
Q
E
L
L
E
R
-----
G
----
E
Q
R
--
A
H
S
A
L
Q
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
S
---
D
R
R
A
L
Q
L
A
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
-
3
PsiBlast_PDB
96.11
99%
-155
- C5 -
4DN0
5
?
A:
[24-321]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
H
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
V
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
Q
E
L
---------------------
A
L
Q
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
------------
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
V
4
PsiBlast_PDB
96.10
100%
-146
- C5 -
4ETZ
1
?
A:
[1-297]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
Y
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
A
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
Q
-----------------------
A
L
Q
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
S
---
D
R
R
A
L
Q
L
A
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
-
9
PsiBlast_CBE
95.42
100%
-146
- C5 -
4ETZ
1
?
B:
[1-297]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
Y
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
A
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
Q
E
L
L
E
-------------------
A
L
Q
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
S
---
D
R
R
A
L
Q
L
A
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
-
30
Fugue
95.23
98%
-151
- C5 -
4DMZ
17
?
A:
[22-321]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
H
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
V
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
A
------------------------
L
Q
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
------------
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
V
2
PsiBlast_PDB
95.21
99%
-152
- C5 -
4DMZ
17
?
A:
[22-321]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
H
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
V
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
------------------------
A
L
Q
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
------------
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
V
5
PsiBlast_PDB
94.51
99%
-145
- C5 -
4EU0
1
?
A:
[1-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
Y
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
A
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
Q
------------------------
A
A
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
S
---
D
R
R
A
L
Q
L
A
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
I
6
PsiBlast_PDB
93.92
99%
-149
- C5 -
4EUV
1
?
A:
[1-297]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
Y
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
A
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
Q
E
L
----------------------
A
A
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
S
---
D
R
R
A
L
Q
L
A
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
-
8
PsiBlast_CBE
93.56
99%
-147
- C5 -
4DMZ
9
?
B:
[22-321]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
Q
S
L
R
S
S
L
L
G
L
R
Q
L
L
R
E
L
P
G
-
D
E
A
P
L
D
A
L
A
E
T
V
L
A
L
L
A
Q
Y
G
----
S
-----
L
R
I
A
G
L
Y
R
V
R
H
D
R
T
P
E
---
P
Q
P
L
A
-
T
L
-------
G
---------
E
--
M
------------
P
V
L
D
A
D
-----
D
L
L
V
R
T
C
L
E
R
G
E
L
V
S
V
R
-----------------------
S
A
L
Q
V
C
V
P
L
V
D
T
D
G
R
I
L
A
L
L
A
V
E
Q
M
P
-
F
-
F
V
F
N
E
R
T
F
S
L
L
A
I
L
A
G
H
I
A
D
L
L
Q
S
-----------
D
I
D
A
Q
R
F
S
Q
Y
L
K
R
S
L
L
D
A
R
D
H
G
L
P
A
C
L
Y
A
F
E
L
T
D
A
R
Y
G
E
E
V
Q
R
L
L
E
G
S
Q
R
G
L
D
V
Q
L
R
L
R
N
D
E
G
R
R
V
L
L
V
L
L
P
L
T
S
A
E
G
S
Q
G
Y
L
Q
R
L
R
I
L
F
A
E
R
F
G
Q
A
R
E
L
E
S
L
G
V
R
I
R
Q
Y
E
L
D
A
G
N
D
R
Q
A
L
G
H
F
L
F
N
E
C
G
L
N
D
Q
Q
V
A
V
21
HHSearch
42.23
12%
-128
- C5 -
3DBA
4
PDE6C_CHICK
A:
[7-172]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
L
F
E
L
L
T
E
I
Q
D
E
A
G
S
M
E
-
K
I
V
H
K
T
L
Q
R
L
S
Q
L
L
----
A
-----
A
D
R
C
S
M
F
I
C
R
S
R
N
-
G
I
---
P
E
V
A
T
-
R
L
LNVTPTS
K
FEDNLVNPD
K
--
E
------------
T
V
F
P
L
D
-----
I
G
I
A
G
W
V
A
H
T
K
K
F
F
N
I
P
D
V
K
K
N
N
HFS--
D
Y
L
D
K
K
T
G
--
Y
T
T
V
N
M
M
A
I
P
I
T
Q
-
G
K
E
V
L
A
V
V
M
A
L
N
K
L
-
N
A
S
E
F
S
K
E
D
E
E
V
F
K
K
Y
L
N
F
I
S
L
V
L
R
------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
42.17
20%
-110
- C5 -
3TRC
2
?
A:
[7-167]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
I
L
R
Q
I
T
Q
E
V
N
A
-
A
P
N
L
E
-
Q
A
L
K
L
V
V
V
R
L
C
E
A
L
----
P
-----
A
D
A
C
S
L
F
I
C
D
D
V
H
-
G
E
---
Y
V
L
M
A
-
T
Q
-------
G
---------
L
--
N
SKQVG
K
------
L
R
L
K
F
G
-----
E
G
L
I
G
L
V
G
E
R
E
E
P
I
N
L
A
D
A
P
L
H
P
A
Y
K
H
R
P
E---
L
G
E
--
E
D
Y
H
G
F
L
G
I
P
I
I
E
-
Q
G
E
L
L
G
I
L
V
I
Q
Q
L
E
-
S
-
H
H
F
A
E
E
E
E
A
F
C
V
T
L
A
I
H
L
A
A
E
I
A
H
---
A
R
A
K
G
A
--------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
41.32
19%
-107
- C5 -
3MMH
14
?
A:
[17-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
L
P
Q
I
E
S
V
V
A
D
-
E
T
D
W
V
-
A
N
L
A
N
T
A
A
V
L
K
E
A
F
----
G
-----
W
F
W
V
G
F
Y
L
V
D
T
R
S
-
D
E
---
L
V
L
A
P
-
F
Q
-------
G
---------
P
--
L
AC----------
T
R
I
P
F
G
-----
R
G
V
C
G
Q
A
W
A
K
G
G
T
V
V
V
G
D
V
D
A
H
P
-----
D
HI--
A
C
S
--
S
L
S
R
S
E
I
V
V
P
L
F
S
-
D
G
R
C
I
G
V
L
D
A
D
S
E
H
-
L
-
A
Q
F
D
E
T
D
A
L
Y
L
G
E
L
A
K
I
L
E
K
R
F
E
A
---
S
R
Q
-----------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
40.00
17%
-120
- C5 -
3KSH
2
?
A:
[17-160]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
K
K
Q
A
A
S
L
I
E
D
-
E
H
H
M
I
-
A
I
L
S
N
M
S
A
L
L
N
D
N
L
D---
Q
-----
I
N
W
V
G
F
Y
L
L
E
Q
N
E
-
L
-----
I
L
G
P
-
F
Q
-------
G
---------
H
--
P
AC----------
V
H
I
P
I
G
-----
K
G
V
C
G
T
A
V
S
E
R
R
T
Q
V
V
A
D
V
H
Q
F
K
-----
G
HI--
A
C
D
--
A
N
S
K
S
E
I
V
V
P
I
F
K
-
D
D
K
I
I
G
V
L
D
I
D
A
P
I
-
T
-
D
R
F
D
D
N
D
K
E
H
L
E
A
I
V
K
I
I
E
K
Q
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
39.40
15%
-113
- C5 -
3RFB
1
?
A:
[20-167]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
E
L
S
F
L
L
E
G
-
E
T
N
V
L
-
A
N
L
S
N
A
S
A
L
I
K
S
R
F
P---
N
-----
T
V
F
A
G
F
Y
L
F
D
G
K
E
------
L
V
L
G
P
-
F
Q
-------
G
---------
G
--
V
SC----------
I
R
I
A
L
G
-----
K
G
V
C
G
E
A
A
H
F
Q
E
T
V
I
V
G
D
V
T
T
Y
L
-----
N
YI--
S
C
D
--
S
L
A
K
S
E
I
V
V
P
M
M
K
-
N
G
Q
L
L
G
V
L
D
L
D
S
S
E
-
I
-
E
D
Y
D
A
M
D
R
D
Y
L
E
Q
F
V
A
I
L
L
E
K
T
T
W
---
D
F
T
M
F
---------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
39.36
13%
-110
- C5 -
1F5M
4
FRMSR_YEAST
A:
[4-179]
----------------------------------------------------------------------------------------------------------------------------------------------
S
T
G
F
H
H
A
D
H
V
N
Y
S
S
N
L
N
K
E
E
I
L
E
Q
L
L
L
S
Y
E
G
L
S
D
-
G
Q
V
N
W
V
C
N
L
S
N
A
S
S
L
I
W
H
A
Y
----
K
S
L
AVD
I
N
W
A
G
F
Y
V
T
Q
A
S
E
E
N
T
---
L
I
L
G
P
-
F
Q
-------
G
---------
K
--
V
AC----------
Q
M
I
Q
F
G
-----
K
G
V
C
G
T
A
A
S
T
K
E
T
Q
I
V
P
D
V
N
K
Y
P
-----
G
----
H
I
A
CD
G
E
T
K
S
E
I
V
V
P
I
I
S
N
D
G
K
T
L
G
V
I
D
I
D
C
L
D
-
Y
-
E
G
F
D
H
V
D
K
E
F
L
E
K
L
A
K
L
I
N
K
S
C
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
39.33
13%
-110
- C5 -
2ZMF
1
PDE10_HUMAN
A:
[13-182]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
L
D
V
S
K
T
Y
F
D
N
I
V
A
I
D
-
S
L
L
E
H
I
M
I
Y
A
K
N
L
V
----
N
-----
A
D
R
C
A
L
F
Q
V
D
H
K
N
-
K
E
---
L
Y
S
D
L
F
D
I
-------
G
---------
E
--
E
KEG
K
P
V
F
K
K
T
KE
I
R
F
S
I
E
-----
K
G
I
A
G
Q
V
A
R
T
G
E
V
L
N
I
P
D
A
Y
A
D
P
RFN--
R
E
V
D
L
Y
T
G
--
Y
T
T
R
N
I
L
C
M
P
I
V
S
-
R
G
S
V
I
G
V
V
Q
M
V
N
K
I
S
G
-
S
A
F
S
K
T
D
E
N
N
F
K
M
F
A
V
F
C
A
L
A
L
H
C
---
A
N
M
Y
H
R
--------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
38.66
15%
-118
- C5 -
3CI6
3
?
A:
[9-169]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
T
L
R
R
I
V
Q
E
I
N
S
-
S
V
S
L
H
-
D
S
L
D
I
M
V
N
Q
V
A
D
A
M
----
K
-----
V
D
V
C
S
I
Y
L
L
D
E
R
N
-
Q
R
---
Y
L
L
M
A
-
S
K
-------
G
---------
L
--
N
PESVGH------
V
S
L
Q
L
S
-----
E
G
L
V
G
L
V
G
Q
R
E
E
I
V
N
L
E
N
A
S
K
H
E
-----
R
F---------
I
Y
N
S
F
L
G
V
P
V
M
Y
-
R
R
K
V
M
G
V
L
V
V
Q
N
K
Q
-
P
-
Q
D
F
S
E
A
A
E
S
F
L
V
T
L
C
A
Q
L
S
G
V
I
A
H
---
A
H
A
V
G
N
--------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
38.07
14%
-112
- C5 -
3E0Y
1
?
A:
[15-172]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
L
E
E
I
S
M
L
V
S
S
-
D
F
D
L
P
-
E
V
L
Q
H
V
T
A
K
V
A
T
Q
L
----
K
-----
V
S
V
C
N
I
Y
L
R
E
G
D
E
-
V
-----
V
L
A
A
-
T
H
-------
G
---------
F
--
D
PAFIGK------
I
R
I
K
I
G
-----
D
G
I
T
G
S
V
A
R
D
G
Q
Y
I
S
L
S
R
A
S
Q
D
P
RY--------------
K
Y
N
S
M
L
S
F
P
I
G
D
-
K
K
E
V
Y
G
V
I
N
L
N
T
T
S
-
I
-
R
S
F
H
E
D
E
I
Y
F
V
S
I
I
A
N
L
I
L
T
A
I
K
L
---
R
Q
Q
V
A
S
--------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
38.04
17%
-90
- C6 -
3ZPJ
-
?
A:
[1-356]
M
T
T
L
E
E
I
N
L
L
V
E
R
G
------------
Y
Y
E
E
A
L
A
K
V
Y
E
I
E
D
P
I
E
Q
V
Q
V
L
T
K
I
V
V
T
I
Y
Q
H
D
G
P
M
E
W
I
P
S
I
M
E
D
A
M
Y
I
A
K
K
L
-----
R
D
P
A
N
K
A
V
A
Y
S
I
I
A
S
T
L
A
I
M
E
Y
E
E
D
A
M
D
F
F
N
R
A
I
D
E
A
N
E
I
E
S
P
I
E
K
G
M
V
L
S
T
L
A
Y
H
L
A
I
----------
A
G
Y
P
D
N
A
L
E
I
F
N
I
A
F
D
T
I
I
G
A
E
T
-
S
Y
T
H
K
V
D
G
I
L
R
I
G
D
L
L
E
K
A
G
D
T
LP
S
-----
N
E
A
M
D
F
Y
K
M
A
F
D
I
F
D
K
L
HV
N
Q
R
A
A
-
I
V
-------
E
---------
K
--
K
------------
I
E
L
A
K
T
V
YDVG
L
P
Q
I
R
A
A
L
L
K
G
K
N
H
Y
A
L
A
I
I
K
K
K
YS---
G
----
V
M
R
--
L
I
G
E
L
E
V
A
L
W
M
K
R
V
N
N
--
M
E
Y
L
D
V
V
D
K
A
-
F
-
E
C
C
E
S
P
R
F
T
--
D
V
N
V
Q
H
I
A
R
L
L
T
E
L
GN
L
R
R
A
L
K
F
A
------------
K
E
I
Q
N
I
H
K
R
S
E
A
L
K
A
I
A
L
E
L
V
R
R
K
K
F
E
E
V
K
K
I
I
E
S
-----------------------
I
P
-------------------------------
D
P
K
I
R
E
E
A
L
N
E
I
G
T
I
E
-------------------
23
HHSearch
37.44
18%
-112
- C5 -
1VHM
1
MSRC_ECOLI
A:
[43-179]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
A
T
L
A
N
T
S
A
L
L
Y
E
R
L
T
----
D
-----
I
N
W
A
G
F
Y
L
L
E
D
D
T
-
L
-----
V
L
G
P
-
F
Q
-------
G
---------
K
IA
C
------------
V
R
I
P
V
G
-----
R
G
V
C
G
T
A
V
A
R
N
Q
V
Q
R
I
E
D
V
H
V
F
D
G----
H
I---
A
C
D
--
A
A
S
N
S
E
I
V
L
P
L
V
V
-
K
N
Q
I
I
G
V
L
D
I
D
S
T
V
-
F
-
G
R
F
T
D
E
D
E
Q
G
L
R
Q
L
V
A
Q
L
E
K
V
L
A
T
---
T
D
Y
K
K
F
--------------------------------------------------------------------------------------------------------------------------------------------