@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3223: (2016-02-15 )
MSRVLVIESSARQRGSVSRLLTAEFISHWKIAHPADRFQVRDLAREPLPHLDELLLGAWTTPCDGHSAAERRALERSNRLTEELRMADVLVLAAPMYNFAIPSSLKSWFDHVLRAGLTFRYAEQGPEGLLQGKRAFVLTARGGIYAGGGLDHQEPYLRQVLGFVGIHDVTFIHAEGMNMGPEFREKGLARARERMRQALETDTSLCVPLPTLR
Atome Classification :
(34 SA)
-.........10..-..-....20........30........40........50........60-.-----.-...-----...70........80........90.....-...100.......110.......120-----........130.......140....-----.--.---.150.......160.......170.......180---........190.......200.......210.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
S
R
V
L
V
IESSARQ-RG-
S
V
S
R
L
L
T
A
E
F
I
S
HWKIAH
P
A
D
R
F
Q
V
R
D
L
A
REPL
P
H
L
D
E
L
L
L
GAWTT-P-----C-DG
H
-----
S
A
A
E
R
R
A
L
E
R
S
N
R
L
T
E
E
L
R
M
A
D
V
L
V
L
AA
P
M
-YNFAI
P
S
S
L
K
S
W
F
D
H
V
L
R
AG
L
T
F
R
Y------AEQG
P
E
G
L
LQG
K
R
A
F
V
L
TARG
G
I
Y
A-----G--G---GLDHQ
E
P
Y
L
R
Q
V
L
G
F
VGI
H
D
V
T
F
I
H
AEGMNM
G
P
----
E
F
R
E
K
G
L
A
R
A
R
E
R
M
R
Q
A
L
ETDTSLCVPLPTLR
50
HHSearch
94.81
48%
-116
* C1 *
1T5B
2
AZOR_SALTY
A:
[1-200]
-
M
S
K
V
L
V
L
K
S
S
I
L
A
--
G
Y
S
Q
S
G
Q
L
T
D
Y
F
I
E
Q
W
R
E
K
H
V
A
D
E
I
T
V
R
D
L
A
A
N
P
V
P
V
L
D
G
E
L
V
G
A
M
R
--------
D
-
A
P
L
-----
T
P
R
Q
Q
D
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
P
T
Q
L
K
N
Y
F
D
L
I
A
R
A
G
I
T
F
R
Y
------
T
E
K
G
P
E
G
L
V
T
G
K
R
A
V
V
L
S
S
R
G
G
I
H
K
-----
D
--
T
---
P
T
D
L
I
A
P
Y
L
K
V
F
L
G
F
I
G
I
T
D
V
N
F
V
F
A
E
G
I
A
Y
G
P
----
E
V
A
A
K
A
Q
A
D
A
K
A
A
I
D
S
V
V
A
-------------
71
Fugue
90.64
44%
-110
- C1 -
1TIK
1
AZOR_ECOLI
A:
[2-204]
S
L
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
R
P
-
S
-----
D
-
A
P
L
-----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
-
A
P
M
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
A
A
I
D
S
I
V
S
A
E
-----------
21
PsiBlast_CBE
90.16
48%
-116
- C1 -
2Z9D
2
AZOR_ECOLI
B:
[1-191]
--
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
R
--
P
-----
S
-
D
A
P
L----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
3
PsiBlast_PDB
89.88
48%
-115
- C1 -
2D5I
3
AZOR_ECOLI
A:
[1-191]
--
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
R
--
P
-----
S
-
D
A
P
L----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
7
PsiBlast_PDB
89.87
48%
-115
- C1 -
2Z9D
2
AZOR_ECOLI
A:
[1-191]
--
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
R
--
P
-----
S
-
D
A
P
L
----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
1
PsiBlast_PDB
88.27
47%
-112
- C1 -
4ESE
6
AZOR_YERPE
A:
[4-202]
-
M
S
K
V
L
V
L
K
S
S
I
L
A
-
T
S
-
S
Q
S
N
Q
L
A
D
F
F
V
E
Q
W
Q
A
A
H
A
G
D
Q
I
T
V
R
D
L
A
A
Q
P
I
P
V
L
D
G
E
L
V
G
A
L
R
P
-
S
-----
G
-
T
A
L
-----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
Q
A
N
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
P
T
Q
L
K
N
Y
F
D
M
I
A
R
A
G
V
T
F
R
Y
------
T
E
K
G
P
E
G
L
V
T
G
K
R
A
I
I
L
T
S
R
G
------------------
D
L
V
V
P
Y
L
R
L
F
L
G
F
I
G
I
T
D
V
E
F
V
F
A
E
G
I
A
Y
G
P
----
E
V
A
T
K
A
Q
A
D
A
K
T
L
L
A
Q
V
V
--------------
9
PsiBlast_PDB
87.81
47%
-112
- C1 -
1TIK
1
AZOR_ECOLI
A:
[3-194]
-
L
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
R
--
P
-----
S
-
D
A
P
L----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
6
PsiBlast_PDB
87.36
48%
-113
- C1 -
2Z9C
3
AZOR_ECOLI
A:
[1-191]
--
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
R
-----------
A
P
L----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
4
PsiBlast_PDB
87.21
48%
-114
- C1 -
2Z98
3
AZOR_ECOLI
A:
[1-191]
--
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
--------------L----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
2
PsiBlast_PDB
86.13
48%
-113
- C1 -
1V4B
3
AZOR_ECOLI
A:
[1-191]
--
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
R
-----------
A
P
L----
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
5
PsiBlast_PDB
86.03
48%
-112
- C1 -
2Z9B
3
AZOR_ECOLI
A:
[1-191]
--
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
N
Q
L
S
D
Y
F
V
E
Q
W
R
E
K
H
S
A
D
E
I
T
V
R
D
L
A
A
N
P
I
P
V
L
D
G
E
L
V
G
A
L
-------------------
T
P
R
Q
Q
E
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
S
T
Q
L
K
N
Y
F
D
L
V
A
R
A
G
V
T
F
R
Y
------
T
E
N
G
P
E
G
L
V
T
G
K
K
A
I
V
I
T
S
R
G
G
I
H
K
-----
D
--
G
---
P
T
D
L
V
T
P
Y
L
S
T
F
L
G
F
I
G
I
T
D
V
K
F
V
F
A
E
G
I
A
Y
G
P
----
E
M
A
A
K
A
Q
S
D
A
K
---------------------
8
PsiBlast_PDB
84.77
50%
-119
- C1 -
1T5B
2
AZOR_SALTY
A:
[1-182]
-
M
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
G
Q
L
T
D
Y
F
I
E
Q
W
R
E
K
H
V
A
D
E
I
T
V
R
D
L
A
A
N
P
V
P
V
L
D
G
E
L
V
G
A
M
R
--------
D
-
A
P
L
-----
T
P
R
Q
Q
D
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
P
T
Q
L
K
N
Y
F
D
L
I
A
R
A
G
I
T
F
R
Y
------
T
E
K
G
P
E
G
L
V
T
G
K
R
A
V
V
L
S
S
R
G
G
I
H
K
-----
D
--
T
---
P
T
D
L
I
A
P
Y
L
K
V
F
L
G
F
I
G
I
T
D
V
N
F
V
F
A
E
G
I
A
Y
G
P
----
E
-------------------------------
22
PsiBlast_CBE
83.87
50%
-117
- C1 -
1T5B
2
AZOR_SALTY
B:
[1-182]
-
M
S
K
V
L
V
L
K
S
S
I
L
A
-
G
Y
-
S
Q
S
G
Q
L
T
D
Y
F
I
E
Q
W
R
E
K
H
V
A
D
E
I
T
V
R
D
L
A
A
N
P
V
P
V
L
D
G
E
L
V
G
A
M
R
----------
A
P
L
-----
T
P
R
Q
Q
D
A
L
A
L
S
D
E
L
I
A
E
L
K
A
H
D
V
I
V
I
A
A
P
M
-
Y
N
F
N
I
P
T
Q
L
K
N
Y
F
D
L
I
A
R
A
G
I
T
F
R
Y
------
T
E
K
G
P
E
G
L
V
T
G
K
R
A
V
V
L
S
S
R
G
G
I
H
K
-----
D
--
T
---
P
T
D
L
I
A
P
Y
L
K
V
F
L
G
F
I
G
I
T
D
V
N
F
V
F
A
E
G
I
A
Y
G
P
----
E
-------------------------------
15
PsiBlast_PDB
83.50
37%
-103
- C1 -
3R6W
11
AZOR1_PSEAE
A:
[1-205]
-
M
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
V
L
DNV-
A
Q
Y
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
E
E
S
G
G
----
R
S
F
E
D
S
C
D
E
A
E
Q
R
L
------------------
14
PsiBlast_PDB
83.39
37%
-105
- C1 -
3LT5
6
AZOR1_PSEAE
A:
[1-205]
-
M
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
V
L
D
NG
V
A
Q
Y
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
E
E
S
G
------
S
F
E
D
S
C
D
E
A
E
Q
R
L
------------------
24
PsiBlast_CBE
81.62
34%
-106
- C1 -
3W7A
8
?
C:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
36
PsiBlast_CBE
81.45
37%
-104
- C1 -
3KEG
4
AZOR1_PSEAE
B:
[2-205]
--
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
V
L
D
NG
V
A
Q
F
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
E
E
--------
S
F
E
D
S
C
D
E
A
E
Q
R
L
------------------
35
PsiBlast_CBE
81.20
37%
-110
- C1 -
3LT5
6
AZOR1_PSEAE
B:
[2-205]
--
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
V------
Q
Y
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
E
E
S
-----------
S
C
D
E
A
E
Q
R
L
------------------
23
PsiBlast_CBE
81.02
34%
-106
- C1 -
3W7A
4
?
D:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
12
PsiBlast_PDB
80.76
34%
-103
- C1 -
3W79
4
?
A:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EK
A
Q
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
52
HHSearch
80.75
34%
-104
- C1 -
3W7A
6
?
A:
[2-210]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
-
A
A
W
G
K
F
A
A
GEG
F
-
E
A
L
-----
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
----
E
K
A
Q
E
I
K
E
A
A
I
A
N
A
R
E
L
A
K
R
------------
30
PsiBlast_CBE
80.43
34%
-105
- C1 -
3W78
2
?
C:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
28
PsiBlast_CBE
80.33
34%
-105
- C1 -
3W79
4
?
B:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
31
PsiBlast_CBE
80.21
34%
-107
- C1 -
3W78
4
?
B:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
13
PsiBlast_PDB
80.14
34%
-105
- C1 -
3W7A
6
?
A:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EK
A
Q
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
27
PsiBlast_CBE
80.07
34%
-105
- C1 -
3W79
4
?
C:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
26
PsiBlast_CBE
79.62
34%
-103
- C1 -
3W79
4
?
D:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
29
PsiBlast_CBE
79.32
34%
-105
- C1 -
3W78
2
?
D:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
25
PsiBlast_CBE
79.11
34%
-101
- C1 -
3W7A
5
?
B:
[2-206]
--
T
K
V
L
F
I
T
A
N
P
N
S
A
E
G
-
S
F
G
M
A
V
G
E
A
F
I
E
A
Y
K
N
E
H
P
Q
D
E
V
V
T
I
D
L
F
N
T
T
V
P
A
I
D
A
D
V
F
A
A
W
G
K
-
F
-----
A
-
A
G
E
GFEAL
T
E
V
Q
Q
Q
K
V
A
A
M
N
T
N
L
E
T
F
M
N
A
D
R
Y
V
F
V
T
P
M
-
W
N
F
S
Y
P
P
V
V
K
A
Y
L
D
N
V
A
I
A
G
K
T
F
K
Y
------
T
E
N
G
P
V
G
L
L
E
G
K
K
A
L
H
I
Q
A
T
G
G
V
Y
S
-----
E
--
G
AYA
A
V
D
F
G
R
N
H
L
K
T
V
L
G
F
V
G
V
N
D
T
E
Y
I
A
V
E
G
M
N
A
N
P
EKAQ
E
I
K
E
A
A
I
A
N
A
R
E
--------------------
33
PsiBlast_CBE
79.05
37%
-106
- C1 -
4N65
5
AZOR1_PSEAE
B:
[2-205]
--
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
V------
Q
Y
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
-------------
D
S
C
D
E
A
E
Q
R
L
------------------
16
PsiBlast_PDB
78.46
37%
-104
- C1 -
2V9C
6
AZOR1_PSEAE
A:
[5-208]
--
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
V
L
DV--
A
Q
Y
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
----------
S
F
E
D
S
C
D
E
A
E
Q
R
L
------------------
32
PsiBlast_CBE
77.64
37%
-108
- C1 -
4N9Q
4
AZOR1_PSEAE
B:
[2-205]
--
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
--------
Y
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
E
------------
D
S
C
D
E
A
E
Q
R
L
------------------
34
PsiBlast_CBE
77.51
37%
-104
- C1 -
3R6W
7
AZOR1_PSEAE
B:
[2-205]
--
S
R
I
L
A
V
H
A
S
P
R
G
-
E
R
-
S
Q
S
R
R
L
A
E
V
F
L
A
A
Y
R
E
A
H
P
Q
A
R
V
A
R
R
E
V
G
R
V
P
L
P
A
V
T
E
A
F
V
A
A
A
F
H
-
P
-----
Q
P
E
Q
R
-----
S
L
A
M
Q
A
D
L
A
L
S
D
Q
L
V
G
E
L
F
D
S
D
L
L
V
I
S
T
P
M
-
Y
N
F
S
V
P
S
G
L
K
A
W
I
D
Q
I
V
R
L
G
V
T
F
D
F
V-----
A
Q
Y
R
P
--
L
L
R
G
K
R
A
L
I
V
T
S
R
G
G
H
G
F
GPGGE
N
--
Q
---
A
M
N
H
A
D
P
W
L
R
T
A
L
G
F
I
G
I
D
E
V
T
V
V
A
A
E
G
E
------------
D
S
C
D
E
A
E
Q
R
L
------------------
10
PsiBlast_PDB
74.36
40%
-100
- C1 -
4C0X
6
AZOR1_PSEPK
A:
[2-184]
---
K
L
L
H
I
D
S
S
I
L
G
-
D
N
-
S
A
S
R
Q
L
S
R
E
V
V
E
A
W
K
A
A
D
P
S
V
E
V
V
Y
R
D
L
A
A
D
A
I
A
H
F
S
A
A
T
L
V
A
A
G
T
-
P
-----
E
-
D
V
R
-----
D
A
A
Q
A
F
E
A
K
L
S
A
E
T
L
E
E
F
L
A
A
D
A
V
V
I
G
A
P
M
-
Y
N
F
T
V
P
T
Q
L
K
A
W
I
D
R
V
A
V
A
G
K
T
F
R
Y
------
T
E
A
G
P
Q
G
L
C
G
N
K
K
V
V
L
V
S
T
A
G
G
L
H
A
-----
G
QP
T
---
G
A
G
H
-
E
D
F
L
K
V
F
L
G
F
I
G
I
T
D
L
E
I
V
R
A
H
G
L
A
Y
G
P
----
E
Q
R
-----------------------------