@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3897: (2016-02-21 )
MNLSLYLLTVLIWGTTWIAIKLQMGPVAITLSIAYRFALAALVLFAVLLLGRRLQRLDARGQRLCMAQGVCLFCLNFICFYTASQWIPSGLVAVVFSTATLWNALNARLWFGQRIASNVMAGGGLGLLGLGLLFWPELVGHQATPETFYGLGLALLGTLCFSTGNMLSSLQQKAGIRPLTGNAWSMLYGTLILLALCLFQGVPLSFDWSARYVGSLLYLAIPGSVIGFTAYLTLVGRMGPDRAAYCTVLFPVVALNISAFAEGYRWTAPALAGLVLVMLGNVLVFRKPKAPALAGPARST
Atome Classification :
(15 SA)
---------------------------------.........10....---....20....-----..-...30.-----.......40....--.--...-50........60........70....-------..------..80.......----.---90.----..-..-.--------------..100--.----------........110-.------------....---..-----.120--------........-----.-130...-...---..140-----------------..---------.....-.150.....------..160------....-.....170...----------------....180....--...---190.......200.---.....------------------.210.----------....-------.-.220.......230-------.........240-...-.-..-----...250.---......260-----.------.....------.270-...-----.....280--..--......290.......300---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------MN
L
S
L
Y
L
L
T
V
L
IWGT---
T
W
I
A
I
-
K
L
QM-----G
P
-
V
A
I
T
L
S
-----
I
A
Y
R
F
A
L
A
A
L
V
L
F
--
A
--
V
L
L
-
L
G
R
R
L
Q
R
L
D
ARG
Q
R
L
C
M
AQ
G
V
C
L
F
C
L
-------
N
F
------
I
C
F
Y
T
A
S
Q
WI
P
----
S
---
G
L
V
----
A
V
-
V
F
-
S
--------------
T
A
T
----
L
----------
W
N
A
L
N
A
R
L
W
F
--
G
------------
Q
R
I
A
---
S
N
-----
V
M----------AGG
G
L
G
L
L
-----
G
-
L
G
-
L
L
F
-
W
P
E
---
L
VGH------------------QA---------
T
P
E
T
F
-
Y
G
L
G
L
A
L
L
G
------
T
L
C
--------FST
G
-
N
M
L
S
S
L
Q
Q
KAG----------------IRPLTG
N
A
W
S
M
--
L
Y
G
---
T
L
I
L
L
A
L
C
L
FQGVP---LSFDW------------------
S
A
R
Y
V
----------
G
S
L
L
-------
Y
-
L
AIPG
S
V
I
G
F
T
A
---------
Y
L
T
L
V
GRMGP---D
R
A
-
A
-
Y
C
-----
T
V
L
F
P
V
V
---
A
L
N
I
S
A
F
AE-----G------YRW
T
A
------
P
A
L
--
A
G
L
-----
V
L
V
M
LG
N
---
V
L
--
V
F
RKPKAPALAGPARST-----
10
Fugue
86.80
19%
-151
- C3 -
4J1Q
1
A:
[20-445]
------------------H
M
E
R
L
M
L
E
P
V
WEKQN
E
E
L
S
Y
T
E
H
I
I
V
L
F
E
T
E
R
S
V
T
D
S
I
-
A
S
H
M
-----
K
D
A
R
V
I
T
L
N
EAVGH
I
A
E
R
Y
Q
C
Y
M
Q
N
I
F
--
E
--
L
L
Q
S
K
V
R
K
L
S
A
G
R
I
I
I
Q
A
I
V
P
L
E
K
E
K
Q
L
F
A
-------
G
V
------
S
G
L
F
K
T
A
E
I
E
F
----
S
---
K
L
T
----
A
Q
-
V
I
-
E
I
EKPEEMID
L
H
L
K
L
K
D
D
----
S
----------
R
R
P
F
D
K
Q
I
R
Y
E
A
G
------------
Y
R
F
V
---
K
G
-----
W
R
E
M
VD
T
L
H
M
PW
R
D
E
G
V
Y
L
I
TGGAG
S
-
L
G
-
L
L
F
-
A
K
E
---
I
A
N
R
T
GR
S
T
I
V
L
T
G
RSVLS
E
D
K
E
N
---------
E
L
E
A
L
-
R
S
I
G
A
E
V
V
Y
READV-
S
D
Q
--------
H
A
V
R
-
H
L
L
E
E
I
K
E
R
Y
G
TLNGIIHG
A
G
S
S
K
D
R
F
I
I
H
K
T
N
E
E
F
Q
E
--
V
L
Q
PK
V
S
G
L
L
H
V
D
E
C
S
K
D
F
P
---
L
D
F
F
I
------------------
F
F
S
S
V
----------
S
G
C
L
GNAGQ
A
D
Y
-
A
A
A
N
S
F
M
D
A
F
A
E
---------
Y
R
R
S
L
A
A
S
K
K
---
R
F
G
-
S
-
T
I
-----
S
F
N
W
P
L
W
EEG
G
M
Q
V
G
A
E
D
E
-----
K
------
R
M
L
K
T
T
GMVPM
P
T
D
--
S
G
L
-----
K
A
F
Y
Q
G
I
---
V
S
----
D
K
P
Q
V
F
V
M
E
G
Q
L
Q
K
M
K
Q
K
LL
17
Fugue
82.87
20%
-163
- C1 -
2W18
5
A:
[24-356]
------------------------------------
N
L
Q
L
V
S
E
L
-------------
K
N
P
S
-----
G
S
-
C
S
V
D
V
S
-----
A
M
F
W
E
K
E
P
C
I
I
T
A
--
C
ED
V
V
S
-
L
W
K
A
L
D
A
W
Q
W
E
K
L
Y
T
W
H
F
A
E
V
P
V
L
Q
I
V
P
V
P
DVY
N
L
------
V
C
V
A
L
G
N
L
E
I
R
----
E
----
I
R
----
A
L
-
F
C
-
E
--------------
K
Q
V
----
L
----------
L
K
S
G
N
I
K
A
V
L
--
G
------------
L
T
K
R
---
R
L
-----
V
S
----------
S
S
G
T
L
S
D
Q
-----
Q
-
V
E
-
V
M
T
-
F
A
E
DGG
G
K
E
N
------------------
Q
F
L
MPPEETIL
T
F
A
E
V
-
Q
G
M
Q
E
A
L
L
G
------
T
T
I
MN
N
I
V
I
W
N
L
K
T
G
-
Q
L
L
K
K
M
H
--
I
D
----------------
D
A
S
V
C
H
K
A
Y
S
E
--
M
-
G
---
L
L
F
I
V
L
S
P
V
F
Q
L
I
V
---
I
N
P
K
-------------------
T
T
L
S
V
----------
G
V
M
L
-------
Y
-
C
L
P
P
G
Q
-----
A
---------
G
R
F
L
E
G
D
V
K
D
---
H
C
A
-
A
-
A
I
L
TSG
T
I
A
I
W
D
L
L
---
L
G
Q
C
T
A
L
L
P
-----
P
VQHWS
F
V
K
W
S
G
------
T
D
S
--
H
L
L
-----
A
G
Q
K
D
G
N
---
I
F
--
V
Y
H
Y
S
-----------------
15
Fugue
80.81
17%
-109
- C3 -
4PE6
1
?
A:
[18-339]
-----------------------------------
K
P
F
I
A
L
S
N
G
F
I
G
N
---
G
W
R
Q
T
M
I
A
K
F
-----
E
E
-
A
A
K
Q
A
Q
-----
A
D
G
L
I
G
K
Y
K
V
V
N
A
--
P
-------
G
N
N
S
A
T
E
Q
V
A
Q
I
K
S
L
L
L
Q
K
P
D
A
L
L
I
-------
N
P
------
A
S
P
T
A
L
Q
P
V
I
Q
Q
A
C
D
A
---
G
V
K
----
V
V
-
V
F
-
D
--------------
S
A
I
DAPC
A
----------
Y
I
L
Q
N
S
F
V
D
W
--
A
------------
T
Y
A
A
---
K
P
-----
V
L
----------
E
S
I
G
---------
G
-
K
G
-
N
V
I
-
V
V
R
---
G
V
V
G
-------------------
S
---------
Q
P
E
A
E
M
Y
E
T
T
K
K
I
L
A
E
Y
PQVK
T
V
A
--------
T
V
T
G
M
C
D
G
A
T
A
Q
K
A
V
L
----------------
G
V
L
P
S
V
S
T
V
D
A
--
V
I
G
C
GD
G
Y
G
V
A
Q
A
F
A
T
A
G
K
P
I
P
A
V
T
F
E
T
------------------
N
G
R
A
L
S
Y
W
K
D
N
KIDN
G
S
V
A
-------
V
M
S
D
P
A
Q
S
V
A
A
L
W
A
---------
A
L
D
L
L
E
G
R
D
L
---
P
K
Q
M
T
-
F
P
-----
I
V
L
I
E
-----
E
K
D
R
D
T
W
A
S
-----
V
------
L
K
P
D
E
------
Y
A
A
--
W
P
W
-----
T
R
E
L
F
R
Q
---
Q
V
--
E
A
I
K
T
G
G
E
P
V
Q
P
P
I
P
S
T
-----
18
Fugue
80.61
16%
-129
- C2 -
4OR2
9
C562_ECOLX (first)
A:
[5-372]
----D
L
E
D
N
W
E
T
L
N
D
N
L
K
V
I
E
K
ADN
A
A
Q
V
K
D
A
L
T
K
M
R
A
A
A
L
D
A
Q
K
A
T
P
---
P
K
L
E
D
-
K
S
P
D
-----
S
P
-
E
M
K
D
F
R
-----
H
G
F
D
I
L
V
G
Q
I
D
D
A
--
L
--
K
L
A
-
N
E
G
K
V
K
E
A
Q
A
A
A
E
Q
L
K
T
T
R
N
A
Y
I
Q
K
Y
-------
L
I
------
P
V
R
Y
L
E
W
S
-
N
I
----
E
---
S
I
I
----
A
I
-
A
F
-
S
--------------
C
L
G
----
I
----------
L
V
T
L
F
V
T
L
I
F
--
V
L
Y
R
DT
P
V
V
K
S
S
S
R
E
L
C
---
Y
I
-----
I
L
----------
A
G
I
F
L
G
Y
V
-----
C
-
P
F
-
T
L
I
-
A
K
P
---
T
T
T
S
------------------
C
Y
---------
L
Q
R
L
L
-
V
G
L
S
S
A
M
C
Y
------
S
A
L
--------
V
T
K
T
-
N
R
I
A
R
I
L
A
R
-------------------
K
P
R
F
M
S
A
W
A
Q
--
V
I
I
---
A
S
I
L
I
S
V
Q
L
T
L
V
V
T
---
L
I
I
M
E
P
P
M
P
I
L
S
Y
PSIK
E
V
Y
L
I
C
N
T
S
N
L
----------
G
V
V
A
-------
P
-
L
G
Y
N
G
L
L
I
M
S
C
T
---------
Y
Y
A
F
K
T
R
N
V
P
ANF
N
E
A
-
K
-
Y
I
-----
A
F
T
M
Y
T
T
---
C
I
I
W
L
A
F
V
P
I
Y
F
G
S
N
------
Y
K
I
I
T
------
T
C
F
--
A
V
S
-----
L
S
V
T
V
A
L
---
G
C
--
M
F
T
P
K
M
Y
I
I
I
A
K
P
E
--------
12
Fugue
73.28
17%
-163
- C3 -
4R1D
-
?
B:
[1-301]
---------------------------------
M
D
K
T
G
W
I
T
H
C
F
--
G
R
---
F
L
I
D
L
-----------
P
-
P
D
A
V
I
N
-----
A
G
Y
Y
L
W
G
D
R
I
E
Y
L
DD
K
--
P
T
E
-
L
A
A
R
V
D
R
L
E
Q
E
W
R
T
Q
R
H
K
S
K
G
N
M
F
L
R
-------
K
I
D
FGNE
S
V
G
L
L
S
W
S
S
E
V
A
----
S
K
T
Y
L
L
D
----
T
Y
-
V
T
-
S
--------------
K
P
T
----
W
H
V
Y
R
W
K
G
K
V
S
V
D
R
E
Q
H
A
V
E
I
--
S
------------
R
A
L
A
---
R
N
-----
L
R
----------
S
R
A
P
K
E
I
P
-----
S
E
P
G
-
F
C
I
D
H
A
Y
---
I
A
G
D
------------------
S
F
---------
Q
V
E
R
F
--
G
V
G
V
T
F
P
E
HPG
A
R
F
E
F
R
--------
S
S
T
G
-
A
E
L
N
S
L
L
E
R
V
------------------
D
G
F
V
Q
N
M
L
S
T
--
F
A
G
---
M
E
T
L
R
K
G
K
H
P
V
G
S
L
---
P
G
------------------------------------
E
E
Y
L
-------
V
-
A
G
S
D
K
G
Q
R
G
Y
T
F
---------
M
W
E
V
Q
G
K
E
E
S
---
L
T
E
-
P
-
N
L
-----
T
A
G
L
A
V
L
---
E
R
S
----
N
E
-----
N
------
G
K
P
P
P
------
P
A
F
KS
D
K
E
-----
A
L
E
L
W
D
T
---
I
V
D
S
I
R
V
R
P
T
S
---------------
14
Fugue
63.43
12%
-124
* C4 *
3B9W
2
?
A:
[8-369]
IN
E
A
R
L
V
A
Q
Y
N
Y
S
I
N
I
L
A
M
L
L
V
G
F
G
F
L
M
VFVRR
Y
G
F
S
A
T
T
G
T
Y
L
V
V
A
T
---
G
L
P
L
Y
-
I
L
L
R
A
N
GIF
G
H
-
A
L
T
P
H
S
-----
V
D
A
V
I
Y
A
E
F
A
V
A
T
--
G
--
L
I
A
-
M
G
A
V
L
G
R
L
R
V
F
Q
Y
A
L
L
A
L
F
I
V
P
V
Y
L
L
-------
N
E
------
W
L
V
L
D
N
A
S
G
L
T
----
E
---
G
F
Q
DSAG
S
I
-
A
I
-
H
--------------
A
F
G
----
A
----------
Y
F
G
L
G
V
S
I
A
L
--
T
------------
T
A
A
Q
R
A
Q
P
I
-----
E
S
----------
D
A
T
S
D
R
F
S
-----
M
-
L
G
S
M
V
L
-
W
L
F
---
W
P
S
F
------------------
A
T
---------
A
I
V
P
F
-
E
Q
M
P
Q
T
I
V
N
------
T
L
L
--------
A
L
C
G
-
A
T
L
A
T
Y
F
L
S
A
L
----------------
F
H
K
G
K
A
S
I
V
D
M
--
A
N
A
AL
A
G
G
V
A
I
G
S
V
C
N
I
V
G
P
---
V
G
A
F
V
------------------
I
G
L
L
G
----------
G
A
I
S
-------
V
-
V
G
F
V
F
I
Q
P
M
L
E
S
KAKTIDTCG
V
H
N
L
H
G
L
P
G
L
---
L
G
G
-
F
-
S
A
-----
I
L
I
V
P
G
I
---
A
V
A
Q
L
T
G
I
G
-----
I
------
T
L
A
L
A
------
L
I
G
--
G
V
I
-----
A
G
A
L
I
K
L
---
T
G
--
T
T
K
Q
A
Y
E
D
S
H
E
F
I
H
L
A
G
PEDE-
1
PsiBlast_PDB
55.41
32%
-73
- C5 -
4GXZ
-
?
A:
[100-173]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Q
Q
F
-
L
A
L
H
E
K
L
M
Q
------
K
R
V
--------
Y
H
T
D
-
D
S
I
K
Q
A
Q
Q
K
A
G
----------------
A
T
P
V
T
L
D
E
K
S
M
E
T
I
R
T
---
N
L
Q
L
A
R
L
V
G
V
Q
G
T
P
---------------------------
A
T
I
I
----------
G
D
E
L
-----------
I
P
G
A
V
-----------------------------------------------------------------------------------------------------------------------------------
16
Fugue
44.17
35%
-49
* C3 *
1JDC
-
?
?:
[358-418]
------------------------------------------------------------------------------------------------------------------------------------------------
R
A
D
S
A
I
S
F
H
S
GY--
S
---
G
L
V
----
A
T
-
V
S
G
S
--------------
Q
Q
T
----
L
----------
V
V
A
L
N
S
D
L
G
N
--
P
------------
G
Q
V
A
---
S
G
S
F
S
E
A
V
N
----------
A
S
N
G
Q
V
R
V
-----
W
-
R
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
42.46
15%
-199
- C- -
3B5D
1
EMRE_ECOLI
A:
[31-105]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
P
S
-------
V
-
G
T
I
I
C
Y
C
A
S
F
W
L
---------
L
A
Q
T
L
A
Y
I
P
T
---
G
I
A
-
Y
A
I
W
-----
S
G
V
G
I
V
L
---
I
S
L
L
S
W
G
F
F
-----
G
------
Q
R
L
D
L
------
P
A
I
--
I
G
M
-----
M
L
I
C
A
G
V
---
L
I
--
I
N
L
L
S
-----------------
19
Fugue
42.26
21%
-122
- C4 -
2JDQ
-
PB2_I75A3
D:
[688-756]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-----
A
V
L
R
G
F
L
---
I
L
G
K
E
D
R
R
Y
-----
G
------
P
A
L
S
I
------
N
E
L
--
S
N
L
AKGEK
A
N
V
L
I
G
Q
GDV
V
L
--
V
M
K
R
K
R
D
S
Q
T
A
T
K
R
I
R
M
-----
5
HHSearch
42.23
17%
-165
- C- -
3B5D
1
EMRE_ECOLI
A:
[32-105]
---------------------------------------------------------------------------------------------------------------------
P
S
V
G
T
I
I
C
Y
C
A
-------
S
F
------
W
L
L
A
Q
T
L
A
Y
I
P
----
T
---
G
I
A
----
Y
A
I
W
S
-
G
--------------
V
G
I
----
V
----------
L
I
S
L
L
S
W
G
F
F
--
G
------------
Q
R
L
D
---
L
P
-----
A
I
----------
I
G
M
M
L
I
C
A
-----
G
-
V
L
-
I
I
N
-
L
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
8.30
18%
179
- C5 -
2ZXE
-
?
G:
[25-41]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
--
V
A
A
-----
V
L
C
V
I
G
I
---
I
I
--
L
L
A
G
------------------
9
HHSearch
5.06
11%
180
- C5 -
3WGU
2
?
G:
[32-48]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
--
F
A
A
-----
L
A
F
I
V
G
L
---
I
I
--
I
L
S
K
------------------
6
HHSearch
0.76
24%
218
* C5 *
2JP3
-
FXYD4_RAT
A:
[23-39]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
--
F
G
G
-----
L
L
C
I
A
G
I
---
A
L
--
A
L
S
G
------------------
7
HHSearch
0.08
14%
0
- C- -
3WU2
-
PSBT_THEVL
T:
[18-9]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
F
F
A
I
F
F
-----
R
------
E
P
P
R
I
-------------------------------------------------------