@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4280: (2016-02-25 )
MQTLLKLLQDGRFHSGEELGAVLGISRSAVWKRLQHLEAEHGLQFHKVRGRGYRLASPLSLLDPRKIDSLWPVEIMPTVDSTNSEAMRRLAAGASTPFVIVAEQQTAGRGRRGRAWVSPYGENLYYSLAITVRGGARELEGLSLVVGLAVLRALESLGVQDTGLKWPNDLLQGGKKIAGILLELSGDPADLCHVVIGIGINVNMKTATDIGQPWTSLREALGELVDRSRLLSALNRQLADYLDRHSREGFAASREEWESCNLWQGAQVILSTALSSIEGRVLGVDSRGALRLEVDGVEQGFSGGELSLRLRQ
Atome Classification :
(73 SA)
.........10-..--.......20........30........40........50........60.......------.70-----.---..-......80........90......-..100.......110.......120.......130.......140.......---.150.....---..160.......170.......180.......190.......200...-.---..---.--210.......220.......230.......240.--......250.....-..260........-.270........280.....-..290...-...-.300.......310
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
Q
T
L
L
K
L
L
QD--GR--FH
S
G
E
E
L
G
A
V
LGI
S
R
S
A
V
W
K
R
L
Q
H
L
E
A
E
HG
L
Q
F
H
K
VRGRG
Y
R
LASPLSLLDPRKID------SL------W---P
V
-
E
I
M
PTVDST
N
S
E
A
M
R
R
L
AAGAST
P
-
F
V
I
V
AEQQTAGRGRRGRAWVSPYGE
N
L
Y
Y
S
L
A
I
T
VRGGARELE
G
-
L
S
L
V
V
G
L
---
A
V
L
R
A
L
E
SL---GVQDTGLKW
P
N
D
L
L
QG
G
K
K
I
A
G
I
L
L
E
LSG
D
P
A
D
L
C
H
V
V
I
G
I
G
I
N
V
N
M
K
-
T
---AT---D--IGQ
P
W
T
S
L
R
E
A
L
G
E
L
V
D
R
S
R
L
L
S
A
L
N
R
Q
L
A
D
Y
L
D
--
R
HSREGFAA
S
R
E
E
W-ESC--NLW
Q
G
A
Q
V
-
I
L
S
-
T
A
L
S
SIE
G
R
V
L
G
VDSR-
G
A
L
R
L
E
VD-GVE-QGFSGG
E
L
S
L
R
LRQ
2
PsiBlast_PDB
92.63
40%
-92
- C6 -
2EWN
1
BIRA_ECOLI
A:
[10-317]
---
L
I
A
L
L
A
N
--
G
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
-
D
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
------
G
Q
------
L
D
G
G
S
V
-
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
R
I
G
E
L
K
S
G
D
-
A
C
I
-
A
E
Y
Q
Q
A
G
R
G
R
R
G
R
K
W
F
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P
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A
N
L
Y
L
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M
F
W
R
L
E
Q
G
P
A
A
A
I
G
-
L
S
L
V
I
G
I
---
V
M
A
E
V
L
R
K
L
---
G
A
D
K
V
R
V
K
W
P
N
D
L
Y
L
Q
D
R
K
L
A
G
I
L
V
E
L
T
G
K
T
G
D
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
R
-
R
---
V
E
---
E
SV
V
N
Q
G
W
I
T
L
Q
E
A
-
G
I
N
L
D
R
N
T
L
A
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L
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L
R
A
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L
F
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Q
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G
L
A
P
Y
L
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R
W
-
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K
L
--
D
N
F
I
N
R
P
V
-
K
L
I
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D
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G
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Q
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L
L
L
E
Q
D
-
G
I
I
-
K
P
W
M
G
G
E
I
S
L
R
---
21
PsiBlast_CBE
91.99
40%
-91
- C6 -
2EWN
1
BIRA_ECOLI
B:
[10-317]
---
L
I
A
L
L
A
N
--
G
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
-
D
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
------
G
Q
------
L
D
G
G
S
V
-
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
R
I
G
E
L
K
S
G
D
-
A
C
I
-
A
E
Y
Q
Q
A
G
R
G
R
R
G
R
K
W
F
S
P
F
G
A
N
L
Y
L
S
M
F
W
R
L
E
Q
G
P
A
A
A
I
G
-
L
S
L
V
I
G
I
---
V
M
A
E
V
L
R
K
L
---
G
A
D
K
V
R
V
K
W
P
N
D
L
Y
L
Q
D
R
K
L
A
G
I
L
V
E
L
T
G
K
T
G
D
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
R
-
R
---
V
E
---
E
SV
V
N
Q
G
W
I
T
L
Q
E
A
-
G
I
N
L
D
R
N
T
L
A
A
M
L
I
R
E
L
R
A
A
L
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--
L
F
E
Q
E
G
L
A
P
Y
L
S
R
W
-
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K
L
--
D
N
F
I
N
R
P
V
-
K
L
I
-
I
G
D
K
E
I
F
G
I
S
R
G
I
D
K
Q
-
G
A
L
L
L
E
Q
D
-
G
I
I
-
K
P
W
M
G
G
E
I
S
L
R
---
1
PsiBlast_PDB
89.07
40%
-88
- C6 -
1HXD
1
BIRA_ECOLI
A:
[10-317]
---
L
I
A
L
L
A
N
--
G
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
-
D
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
------
G
Q
------
L
DG
G
S
V
-
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
R
I
G
E
L
K
S
G
D
-
A
C
I
-
A
E
Y
Q
Q
A
G
R
G
R
R
G
R
K
W
F
S
P
F
G
A
N
L
Y
L
S
M
F
W
R
L
E
Q
G
P
A
A
A
I
G
-
L
S
L
V
I
G
I
---
V
M
A
E
V
L
R
K
L
---
G
A
D
K
V
R
V
K
W
P
N
D
L
Y
L
Q
D
R
K
L
A
G
I
L
V
E
L
T
G
K
T
G
D
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
----------------
Q
G
W
I
T
L
Q
E
A
-
G
I
N
L
D
R
N
T
L
A
A
M
L
I
R
E
L
R
A
A
L
E
--
L
F
E
Q
E
G
L
A
P
Y
L
S
R
W
-
E
K
L
--
D
N
F
I
N
R
P
V
-
K
L
I
-
I
G
D
K
E
I
F
G
I
S
R
G
I
D
K
Q
-
G
A
L
L
L
E
Q
D
-
G
I
I
-
K
P
W
M
G
G
E
I
S
L
R
---
4
PsiBlast_PDB
88.86
40%
-95
- C6 -
1BIB
1
BIRA_ECOLI
A:
[10-317]
---
L
I
A
L
L
A
N
--
G
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
-
D
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
------
G
Q
------
L
DG
G
S
V
-
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
R
I
G
E
L
K
S
G
D
-
A
C
I
-
A
E
Y
Q
Q
A
G
R
G
R
------
S
P
F
G
A
N
L
Y
L
S
M
F
W
R
L
E
Q
-
P
A
A
A
I
G
-
L
S
L
V
I
G
I
---
V
M
A
E
V
L
R
K
L
---
G
A
D
K
V
R
V
K
W
P
N
D
L
Y
L
Q
D
R
K
L
A
G
I
L
V
E
L
T
G
----
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
------------------
W
I
T
L
Q
E
A
-
G
I
N
L
D
R
N
T
L
A
A
M
L
I
R
E
L
R
A
A
L
E
--
L
F
E
Q
E
G
L
A
P
Y
L
S
R
W
-
E
K
L
--
D
N
F
I
N
R
P
V
-
K
L
I
-
I
G
D
K
E
I
F
G
I
S
R
G
I
D
K
Q
-
G
A
L
L
L
E
Q
D
-
G
I
I
-
K
P
W
M
G
G
E
I
S
L
R
---
22
PsiBlast_CBE
88.44
40%
-87
- C6 -
1HXD
1
BIRA_ECOLI
B:
[10-317]
---
L
I
A
L
L
A
N
--
G
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
-
D
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
------
G
Q
------
L
DGG
S
V
-
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
R
I
G
E
L
K
S
G
D
-
A
C
I
-
A
E
Y
Q
Q
A
G
R
G
R
R
G
R
K
W
F
S
P
F
G
A
N
L
Y
L
S
M
F
W
R
L
E
Q
G
P
A
A
A
I
G
-
L
S
L
V
I
G
I
---
V
M
A
E
V
L
R
K
L
---
G
A
D
K
V
R
V
K
W
P
N
D
L
Y
L
Q
D
R
K
L
A
G
I
L
V
E
L
T
G
K
T
G
D
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
----------------
Q
G
W
I
T
L
Q
E
A
-
G
I
N
L
D
R
N
T
L
A
A
M
L
I
R
E
L
R
A
A
L
E
--
L
F
E
Q
E
G
L
A
P
Y
L
S
R
W
-
E
K
L
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D
N
F
I
N
R
P
V
-
K
L
I
-
I
G
D
K
E
I
F
G
I
S
R
G
I
D
K
Q
-
G
A
L
L
L
E
Q
D
-
G
I
I
-
K
P
W
M
G
G
E
I
S
L
R
---
3
PsiBlast_PDB
86.87
40%
-97
- C6 -
1BIA
-
BIRA_ECOLI
A:
[10-317]
---
L
I
A
L
L
A
N
--
G
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
-
D
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
------
G
Q
------
L
DG
G
S
V
-
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
R
I
G
E
L
K
S
G
D
-
A
C
I
-
A
E
Y
Q
Q
A
G
---------
S
P
F
G
A
N
L
Y
L
S
M
F
W
R
L
E
Q
-
P
A
A
A
I
G
-
L
S
L
V
I
G
I
---
V
M
A
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V
L
R
K
L
---
G
A
D
K
V
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V
K
W
P
N
D
L
Y
L
Q
D
R
K
L
A
G
I
L
V
E
L
T
G
----
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
------------------
W
I
T
L
Q
E
A
-
G
I
N
L
D
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N
T
L
A
A
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L
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R
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L
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A
A
L
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L
F
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L
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L
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N
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L
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R
G
I
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A
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L
L
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Q
D
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G
I
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K
P
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M
G
G
E
I
S
L
R
---
113
HHSearch
86.84
40%
-99
- C6 -
1BIA
-
BIRA_ECOLI
A:
[8-317]
-
L
K
L
I
A
L
L
A
N
--
G
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
D
-
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
------
G
Q
LD----
G
G
--
S
V
-
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
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G
-
E
L
K
S
G
-
D
A
C
I
A
E
Y
Q
Q
A
G
---------
S
P
F
G
A
N
L
Y
L
S
M
F
W
R
L
E
Q
-
P
A
A
A
I
G
-
L
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L
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I
---
V
M
A
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V
L
R
K
L
---
G
A
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K
W
P
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Y
L
Q
D
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L
A
G
I
L
V
E
L
T
G
----
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
------------------
W
I
T
L
Q
E
A
G
-
I
N
L
D
R
N
T
L
A
A
M
L
I
R
E
L
R
A
A
L
E
--
L
F
E
Q
E
G
L
A
P
Y
L
S
R
W
-
E
K
L
--
D
N
F
I
N
R
P
V
-
K
L
I
-
I
G
D
K
E
I
F
G
I
S
R
G
I
D
K
Q
-
G
A
L
L
L
E
Q
D
-
G
I
I
-
K
P
W
M
G
G
E
I
S
L
R
---
10
PsiBlast_PDB
80.64
25%
-92
- C6 -
3RKY
1
?
A:
[6-304]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
-
N
A
A
S-
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
8
PsiBlast_PDB
80.56
25%
-95
- C6 -
3RKW
1
?
A:
[6-304]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
-
N
A
A
S-
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
16
PsiBlast_PDB
80.23
25%
-97
- C6 -
3V8K
1
?
A:
[12-310]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
--
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
7
PsiBlast_PDB
79.96
25%
-93
- C6 -
3RIR
1
?
A:
[6-304]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
-
N
A
A
S-
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
17
PsiBlast_PDB
79.83
25%
-93
- C6 -
3V8L
1
?
A:
[12-310]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
--
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
6
PsiBlast_PDB
79.83
25%
-93
- C6 -
4HA8
1
?
A:
[11-309]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
-
N
A
A
S-
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
11
PsiBlast_PDB
79.78
25%
-94
- C6 -
4DQ2
1
?
A:
[5-303]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
--
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
12
PsiBlast_PDB
79.74
25%
-92
- C6 -
3V7C
1
?
A:
[6-304]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
--
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
14
PsiBlast_PDB
79.58
25%
-94
- C6 -
3V7R
1
?
A:
[12-310]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
--
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
13
PsiBlast_PDB
79.20
25%
-97
- C6 -
3V7S
1
?
A:
[6-304]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
--
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
112
HHSearch
78.83
24%
-101
- C6 -
3RKX
-
?
A:
[7-323]
--
D
V
L
Q
L
L
Y
K
N
K
P
N
--
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
-
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
------
Q
Y
T
K
S
SAL
F
D--
F
S
-
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
------------
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
ENF
D
E
---
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
-
N
A
A
--
S
N
I
W
N
R
T
L
-
L
F
T
-
E
N
-
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
I
V
R
D
E
A
G
E
S
-
H
R
L
I
S
A
D
I
D
F
----
9
PsiBlast_PDB
77.52
25%
-103
- C6 -
3RKX
-
?
A:
[6-304]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
T
------------
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
-
N
A
A
S-
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
-
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
15
PsiBlast_PDB
76.84
25%
-104
- C6 -
3V8J
-
?
A:
[5-303]
-
Q
D
V
L
Q
L
L
Y
K
--
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
-
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
------
F
---
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
-
G
N
Q
S
S
-
F
F
I
L
S
D
E
Q
---------------
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
-
F
N
L
F
I
A
L
---
G
I
R
D
A
I
Q
H
F
---
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
---
E
N
FDE
S
--
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
--
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
--
N
I
W
N
R
T
-
L
-
L
F
T
-
E
N
-
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
-
G
Y
L
------------------------
25
PsiBlast_CBE
72.05
32%
-86
- C6 -
4XU3
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
--
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
38
PsiBlast_CBE
71.62
32%
-88
- C6 -
4XTX
2
?
A:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
24
PsiBlast_CBE
71.57
33%
-85
- C6 -
3EFS
4
?
B:
[8-231]
-----------------------------------------------------------------------------------------------
L
K
E
V
D
S
T
Q
-
E
R
L
K
E
W
N
V
S
Y
G
T
---
A
L
V
A
D
R
Q
T
K
G
R
G
R
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
----
P
K
E
F
E
N
-
L
L
Q
L
P
L
V
LGL
S
V
S
E
A
L
E
E
I
---
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
-----
K
L
I
V
G
I
G
I
N
V
N
Q
R
E
I
---
P
E
---
E
--
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
--
K
F
K
E
K
S
F
K
E
F
K
G
K
I
-
E
S
K
--
M
L
Y
L
G
E
E
V
-
K
L
--
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
-
G
I
K
-
E
I
L
S
-
G
E
F
S
L
R
---
35
PsiBlast_CBE
71.38
32%
-84
- C6 -
4XTY
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
--
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
32
PsiBlast_CBE
71.27
32%
-85
- C6 -
4XU0
1
?
A:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
19
PsiBlast_PDB
71.17
33%
-90
- C6 -
3EFS
5
?
A:
[8-231]
-----------------------------------------------------------------------------------------------
L
K
E
V
D
S
T
Q
-
E
R
L
K
E
W
N
V
S
Y
G
T
---
A
L
V
A
D
R
Q
T
K
G
R
G
R
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
----
P
K
E
F
E
N
-
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
---
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
-----
K
L
I
V
G
I
G
I
N
V
N
Q
R
E
I
---
P
E
---
E
--
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
--
K
F
K
E
K
S
F
K
E
F
K
G
K
I
-
E
S
K
--
M
L
Y
L
G
E
E
V
-
K
L
--
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
-
G
I
K
-
E
I
L
S
-
G
E
F
S
L
R
---
36
PsiBlast_CBE
71.15
32%
-83
- C6 -
4XTY
1
?
A:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
34
PsiBlast_CBE
71.11
32%
-85
- C6 -
4XTZ
1
?
A:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
42
PsiBlast_CBE
71.05
32%
-86
- C6 -
4XTV
1
?
A:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
31
PsiBlast_CBE
70.87
32%
-84
- C6 -
4XU0
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
--
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
40
PsiBlast_CBE
70.83
32%
-85
- C6 -
4XTW
2
?
A:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
44
PsiBlast_CBE
70.79
32%
-84
- C6 -
3RUX
1
?
A:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
27
PsiBlast_CBE
70.71
32%
-83
- C6 -
4XU2
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
I-----
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
41
PsiBlast_CBE
70.67
32%
-81
- C6 -
4XTV
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
--
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
46
PsiBlast_CBE
70.66
32%
-88
- C6 -
4OP0
1
?
A:
[32-264]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
I------
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
39
PsiBlast_CBE
70.54
32%
-90
- C6 -
4XTW
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV----
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
48
PsiBlast_CBE
69.81
33%
-78
- C6 -
3EFR
4
?
A:
[8-231]
-----------------------------------------------------------------------------------------------
L
K
E
V
D
S
T
Q
-
E
R
L
K
E
W
N
V
S
Y
G
T
---
A
L
V
A
D
R
Q
T
K
G
R
G
G
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
----
P
K
E
F
E
N
-
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
---
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
-----
K
L
I
V
G
I
G
I
N
V
N
Q
R
E
I
---
P
E
---
E
--
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
--
K
F
K
E
K
S
F
K
E
F
K
G
K
I
-
E
S
K
--
M
L
Y
L
G
E
E
V
-
K
L
--
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
-
G
I
K
-
E
I
L
S
-
G
E
F
S
L
R
---
45
PsiBlast_CBE
69.34
32%
-86
- C6 -
4OP0
2
?
B:
[32-264]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IA----
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
29
PsiBlast_CBE
68.98
32%
-87
- C6 -
4XU1
2
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV
P
P
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
33
PsiBlast_CBE
68.73
32%
-85
- C6 -
4XTZ
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV--
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
47
PsiBlast_CBE
68.63
33%
-74
- C6 -
3EFR
3
?
B:
[8-231]
-----------------------------------------------------------------------------------------------
L
K
E
V
D
S
T
Q
-
E
R
L
K
E
W
N
V
S
Y
G
T
---
A
L
V
A
D
R
Q
T
K
G
R
G
G
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
----
P
K
E
F
E
N
-
L
L
Q
L
P
L
V
LGL
S
V
S
E
A
L
E
E
I
---
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
-----
K
L
I
V
G
I
G
I
N
V
N
Q
R
E
I
---
P
E
---
E
--
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
--
K
F
K
E
K
S
F
K
E
F
K
G
K
I
-
E
S
K
--
M
L
Y
L
G
E
E
V
-
K
L
--
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
-
G
I
K
-
E
I
L
S
-
G
E
F
S
L
R
---
62
PsiBlast_CBE
68.58
33%
-110
- C6 -
2DJZ
1
?
B:
[36-232]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
------
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
57
PsiBlast_CBE
68.01
33%
-112
- C6 -
1WQW
1
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
72
PsiBlast_CBE
67.84
33%
-115
- C6 -
2DZ9
1
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
A
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
70
PsiBlast_CBE
67.81
33%
-112
- C6 -
2DEQ
1
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
G
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
65
PsiBlast_CBE
67.76
33%
-109
- C6 -
2EJG
2
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
------
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
59
PsiBlast_CBE
67.74
33%
-109
- C6 -
1WNL
2
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
43
PsiBlast_CBE
67.68
32%
-81
- C6 -
3RUX
1
?
B:
[34-266]
-------------------------------------------------------------------------------------------
L
-
D
V
V
A
Q
T
G
S
T
N
A
D
L
L
A
R
A
A
S
G
A
D
I
D
G
V
V
L
I
A
E
H
Q
T
A
G
R
G
R
H
G
R
G
W
A
A
T
A
R
A
Q
I
I
L
S
V
G
V
R
V
V
D
V
P
V
Q
A
W
G
W
L
S
L
A
A
G
L
---
A
V
L
D
S
V
A
P
L
IAV--
A
E
T
G
L
K
W
P
N
D
V
L
A
R
G
G
K
L
A
G
I
L
A
E
V
A
-----
Q
P
F
V
V
L
G
V
G
L
N
V
T
-
Q
-
A
---
P
E
---
E
--
V
D
P
D
A
T
S
L
L
D
L
G
V
A
A
P
D
R
N
R
I
A
S
R
L
L
R
E
L
E
A
R
I
I
Q
W
R
N
A
N
P
Q
L
A
A
---
D
Y
-
R
A
R
--
S
L
T
I
G
S
R
V
-
R
V
E
L
P
G
G
Q
D
V
V
G
I
A
R
D
I
D
D
Q
-
G
R
L
C
L
D
V
G
-
G
R
T
-
V
V
V
S
A
G
D
V
------
74
PsiBlast_CBE
67.48
33%
-116
- C6 -
2DXT
2
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
A
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
54
PsiBlast_CBE
67.44
33%
-112
- C6 -
2DKG
3
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
68
PsiBlast_CBE
67.36
33%
-114
- C6 -
2DVE
1
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
A
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
67
PsiBlast_CBE
67.29
33%
-110
- C6 -
2DVE
1
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
A
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
77
PsiBlast_CBE
67.24
32%
-108
- C6 -
2EJF
2
?
B:
[36-231]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
-------
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
-----
73
PsiBlast_CBE
67.21
33%
-111
- C6 -
2DXT
2
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
A
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
56
PsiBlast_CBE
67.13
33%
-114
- C6 -
1X01
1
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
80
PsiBlast_CBE
66.83
32%
-115
- C6 -
2E41
1
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
69
PsiBlast_CBE
66.68
33%
-106
- C6 -
2DEQ
1
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
G
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
63
PsiBlast_CBE
66.66
33%
-113
- C6 -
2DJZ
1
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
50
PsiBlast_CBE
66.62
33%
-114
- C6 -
2DTI
3
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
66
PsiBlast_CBE
66.61
33%
-106
- C6 -
2DXU
1
?
B:
[36-226]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K--------
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
----------
79
PsiBlast_CBE
66.59
32%
-108
- C6 -
2E41
1
?
B:
[36-232]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
58
PsiBlast_CBE
66.58
33%
-112
- C6 -
1WQW
1
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
71
PsiBlast_CBE
66.52
33%
-106
- C6 -
2DZ9
1
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
A
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
60
PsiBlast_CBE
66.52
33%
-110
- C6 -
1WNL
2
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
75
PsiBlast_CBE
66.40
32%
-112
- C6 -
2ZGW
2
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
-
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
55
PsiBlast_CBE
66.23
33%
-107
- C6 -
1X01
4
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
53
PsiBlast_CBE
66.18
33%
-107
- C6 -
2DKG
1
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
49
PsiBlast_CBE
66.17
33%
-111
- C6 -
2DTI
3
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
52
PsiBlast_CBE
66.08
33%
-108
- C6 -
2DTH
2
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
78
PsiBlast_CBE
65.91
32%
-109
- C6 -
2EJF
3
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
64
PsiBlast_CBE
65.86
33%
-107
- C6 -
2EJG
2
?
B:
[36-231]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
--------
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
----
E
V
K
K
V
I
Y
G
D
V
S
-----
76
PsiBlast_CBE
65.69
32%
-113
- C6 -
2ZGW
2
?
A:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--
51
PsiBlast_CBE
65.50
33%
-106
- C6 -
2DTH
2
?
B:
[36-234]
-----------------------------------------------------------------------------------------------------------------------
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
-
I
V
F
L
G
A
V
---
G
V
V
E
T
L
K
E
F
---
S
I
-
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
---
P
N
---
G
--
A
----
T
S
M
K
L
E
L
G
S
E
V
P
---
L
L
S
V
F
-
R
S
L
I
T
N
L
D
--
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
-
N
L
V
RD
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
--
S
F
E
G
I
A
E
D
I
D
D
F
-
G
R
L
I
I
R
L
D
-
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
--