@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4461: (2016-02-27 )
MATLKAQHLAKSYKGRQVVRDVSMSIDSGQIVGLLGPNGAGKTTCFYMIVGLVQADQGVVRIDEQNVTHLPMHGRARAGIGYLPQEASIFRKLSVSDNIMAILETRSDLDRNGRKEALEGLLQEFHIHHIRDNLGMSLSGGERRRVEIARALASAPKFILLDEPFAGVDPISVGDIKQIIHHLKAKGIGILITDHNVRETLDICETAYIVNDGQLIAEGDAESILANDLVKEVYLGHEFRL
Atome Classification :
(21 SA)
.........10...-.----....20........30........40........50........60........70..--.--.....80........90........100....----..-----.----------.--.110.......120--------.....-....130.......140.......150.......160.......170.......180...-.-...190.......200.......210.......220----.....---..230.--.-----------------------.....240-------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAT
L
K
A
Q
H
L
A
K
S
YK-G----
R
Q
V
V
R
D
V
SMSIDS
G
Q
I
V
G
L
LGPNGAGK
T
T
C
F
Y
M
I
V
G
L
V
QADQ
G
V
V
R
IDEQNVTHLPMH--G--RARAGIGYLP
Q
E
A
S
I
F
R
KLSVSD
N
I
M
--
A
I
L
E
----
T
R
-----
S
----------D--LDRN
G
R
K
E
A
L
E
G
----------
L
L
Q
E
F
-
H
I
H
H
I
R
D
NLGMSLSGG
E
R
R
R
V
E
I
A
R
A
L
ASA
P
K
F
I
L
LDEPFAGVDPI
S
V
G
D
I
K
Q
I
I
H
H
L
K
A-K-
G
I
G
I
L
I
TDH
N
V
R
E
T
L
D
I
CE
T
A
Y
I
VND
G
Q
L
I
AEG
D
A
E
----
S
I
L
A
N
---
D
L
V
K
E
V
--Y-----------------------LGHEFRL--------------------------------------------------------------------
23
PsiBlast_CBE
97.44
65%
-121
- C1 -
4P33
6
LPTB_ECOLI
B:
[1-235]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
H
--
A
--
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
--
A
V
L
Q
----
I
R
-----
D
----------
D
--
L
S
A
E
Q
R
E
D
R
A
N
E
----------
L
M
E
E
F
-
H
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
----
E
I
L
Q
D
---
E
H
V
K
R
V
--
Y
-----------------------
L
G
-------------------------------------------------------------------------
3
PsiBlast_PDB
97.41
65%
-122
- C1 -
4P33
7
LPTB_ECOLI
A:
[1-235]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
H
--
A
--
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
--
A
V
L
Q
----
I
R
-----
D
----------
D
--
L
S
A
E
Q
R
E
D
R
A
N
E
----------
L
M
E
E
F
-
H
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
----
E
I
L
Q
D
---
E
H
V
K
R
V
--
Y
-----------------------
L
G
-------------------------------------------------------------------------
2
PsiBlast_PDB
96.87
66%
-118
- C1 -
4P32
2
LPTB_ECOLI
A:
[1-234]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
H
--
A
--
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
--
A
V
L
Q
----
I
R
-----
D
----------
D
--
L
S
A
E
Q
R
E
D
R
A
N
E
----------
L
M
E
E
F
-
H
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
----
E
I
L
Q
D
---
E
H
V
K
R
V
--
Y
-----------------------
L
--------------------------------------------------------------------------
1
PsiBlast_PDB
96.59
66%
-119
- C1 -
4QC2
2
?
A:
[2-236]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
H
--
A
--
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
--
A
V
L
Q
----
I
R
-----
D
----------
D
--
L
S
A
E
Q
R
E
D
R
A
N
E
----------
L
M
E
E
F
-
H
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
----
E
I
L
Q
D
---
E
H
V
K
R
V
--
Y
-----------------------
L
G
-------------------------------------------------------------------------
21
PsiBlast_CBE
96.06
66%
-123
- C1 -
4QC2
2
?
B:
[2-236]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
H
--
A
--
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
--
A
V
L
Q
----
I
R
-----
D
----------
D
--
L
S
A
E
Q
R
E
D
R
A
N
E
----------
L
M
E
E
F
-
H
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
----
E
I
L
Q
D
---
E
H
V
K
R
V
--
Y
-----------------------
L
G
-------------------------------------------------------------------------
22
PsiBlast_CBE
95.83
66%
-119
- C1 -
4P32
2
LPTB_ECOLI
B:
[1-230]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
H
--
A
--
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
--
A
V
L
Q
----
I
R
-----
D
----------
D
--
L
S
A
E
Q
R
E
D
R
A
N
E
----------
L
M
E
E
F
-
H
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
----
E
I
L
Q
D
---
E
H
V
K
-------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
93.42
55%
-121
- C1 -
4WBS
1
?
B:
[38-282]
-
S
S
L
V
V
R
N
L
K
K
R
Y
G
-
S
----
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
K
S
I
S
L
L
P
I
H
--
K
--
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
V
F
R
K
L
S
V
E
E
N
I
R
--
A
V
L
E
----
L
Q
VGG--
K
----------
R
--
L
S
K
D
A
I
A
S
R
T
E
A
----------
L
L
D
E
L
-
Q
I
S
H
L
R
E
N
P
A
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
-
R
-
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
----
D
I
I
E
N
---
E
S
V
R
R
V
--
Y
-----------------------
L
G
E
H
F
R
M
--------------------------------------------------------------------
5
PsiBlast_PDB
91.91
55%
-124
- C1 -
4WBS
1
?
A:
[38-282]
-
S
S
L
V
V
R
N
L
K
K
R
Y
G
-
S
----
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
K
S
I
S
L
L
P
I
H
--
K
--
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
V
F
R
K
L
S
V
E
E
N
I
R
--
A
V
L
E
----
L
Q
VGDDG
K
----------
R
--
L
S
K
D
A
I
A
S
R
T
E
A
----------
L
L
D
E
L
-
Q
I
S
H
L
R
E
N
P
A
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
-
R
-
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
----
D
I
I
E
N
---
E
S
V
R
R
V
--
Y
-----------------------
L
G
E
H
F
R
M
--------------------------------------------------------------------
6
PsiBlast_PDB
77.08
34%
-118
- C1 -
1JI0
1
?
A:
[6-238]
--
V
L
E
V
Q
S
L
H
V
Y
Y
G
-
A
----
I
H
A
I
K
G
I
D
L
K
V
P
R
G
Q
I
V
T
L
I
G
A
N
G
A
G
K
T
T
T
L
S
A
I
A
G
L
V
R
A
Q
K
G
K
I
I
F
N
G
Q
D
I
T
N
K
P
A
H
--
V
--
I
N
R
M
G
I
A
L
V
P
E
G
R
R
I
F
P
E
L
T
V
Y
E
N
L
M
--
M
G
A
Y
----
N
R
-----
K
----------
D
----
K
E
G
I
K
R
D
L
E
W
----------
I
F
S
L
F
P
R
L
K
E
R
L
K
Q
L
G
G
T
L
S
G
G
E
Q
Q
M
L
A
I
G
R
A
L
M
S
R
P
K
L
L
M
M
D
E
P
S
L
G
L
A
P
I
L
V
S
E
V
F
E
V
I
Q
K
I
N
Q
-
E
-
G
T
T
I
L
L
V
E
Q
N
A
L
G
A
L
K
V
A
H
Y
G
Y
V
L
E
T
G
Q
I
V
L
E
G
K
A
S
----
E
L
L
D
N
---
E
M
V
R
K
A
--
Y
-----------------------
L
G
-------------------------------------------------------------------------
67
HHSearch
75.63
35%
-115
- C1 -
1JI0
1
?
A:
[6-233]
--
V
L
E
V
Q
S
L
H
V
Y
Y
G
-
A
----
I
H
A
I
K
G
I
D
L
K
V
P
R
G
Q
I
V
T
L
I
G
A
N
G
A
G
K
T
T
T
L
S
A
I
A
G
L
V
R
A
Q
K
G
K
I
I
F
N
G
Q
D
I
T
N
K
P
A
H
--
V
--
I
N
R
M
G
I
A
L
V
P
E
G
R
R
I
F
P
E
L
T
V
Y
E
N
L
M
--
M
G
A
Y
----
N
R
-----
K
--------------
D
K
E
G
I
K
R
D
L
E
W
----------
I
F
S
L
F
P
R
L
K
E
R
L
K
Q
L
G
G
T
L
S
G
G
E
Q
Q
M
L
A
I
G
R
A
L
M
S
R
P
K
L
L
M
M
D
E
P
S
L
G
L
A
P
I
L
V
S
E
V
F
E
V
I
Q
K
I
N
Q
-
E
-
G
T
T
I
L
L
V
E
Q
N
A
L
G
A
L
K
V
A
H
Y
G
Y
V
L
E
T
G
Q
I
V
L
E
G
K
A
S
----
E
L
L
D
N
---
E
M
V
R
-------------------------------------------------------------------------------------------------------
70
HHSearch
71.61
31%
-104
- C1 -
1G6H
3
LIVG_METJA
A:
[5-243]
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
-
E
----
F
K
A
L
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
E
P
A
--
E
--
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
--
I
G
E
I
----
C
P
-----
G
ES
P
L
N
S
L
F
Y
K
K
WI
P
K
E
E
E
M
V
E
K
A
F
K
----------
I
L
E
F
L
-
K
L
S
H
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
-
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
G
Q
I
I
A
E
G
R
G
E
----
E
E
I
K
N
--------------------------------------------------------------------------------------------------------------
49
Fugue
69.94
28%
-117
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
-
H
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
GTRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--
E
LT
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
--
L
P
L
E
----
L
D
----------------
N
--
T
P
K
D
E
V
K
R
R
V
T
E
----------
L
L
S
L
V
-
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
----
E
V
F
S
H
PKT
P
L
A
Q
K
F
--
I
QSTLHLDIPEDYQERLQAEPFTD
C
V
P
M
L
R
L
EFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
54
HHSearch
68.89
30%
-108
- C1 -
1Z47
1
?
A:
[14-237]
--
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
----
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
T
D
L
P
P
-------
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
--
F
G
L
R
----
E
K
-----
R
-------------
V
P
K
D
E
M
D
A
R
V
R
E
----------
L
L
R
F
M
-
R
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
-
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
----
E
V
Y
E
K
---
P
----------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
68.82
30%
-106
- C1 -
1G6H
3
LIVG_METJA
A:
[5-257]
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
-
E
----
F
K
A
L
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
E
P
A
--
E
--
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
I
C
P
----
G
E
-----
S
----------
P
--
L
N
S
L
F
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
-
K
L
S
H
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
-
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
S
D
---
P
K
V
V
E
I
--
Y
-----------------------
I
G
E
------------------------------------------------------------------------
62
HHSearch
68.37
28%
-104
* C1 *
3TUI
1
METN_ECOLI
C:
[23-255]
-
H
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
GTRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
EL
T
--
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
--
L
P
L
E
----
L
D
-----
N
-------------
T
P
K
D
E
V
K
R
R
V
T
E
----------
L
L
S
L
V
-
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
----
E
V
F
S
H
---
P
----------------------------------------------------------------------------------------------------------
56
HHSearch
67.60
27%
-108
- C1 -
2IT1
-
?
A:
[1-225]
M
V
E
I
K
L
E
N
I
V
K
K
F
G
-
N
----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
K
D
V
T
E
L
P
-------
P
K
D
R
N
V
G
L
V
F
Q
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
--
F
P
L
E
----
L
R
-----
K
-------------
A
P
R
E
E
I
D
K
K
V
R
E
----------
V
A
K
M
L
-
H
I
D
K
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
-
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
----
E
V
Y
Y
K
---
P
----------------------------------------------------------------------------------------------------------
60
HHSearch
66.62
26%
-111
- C1 -
3RLF
3
MALK_ECOLI
A:
[2-226]
-
A
S
V
Q
L
Q
N
V
T
K
A
W
G
-
E
----
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
R
M
N
D
T
P
-------
P
A
E
R
G
V
G
M
V
F
Q
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
--
F
G
L
K
----
L
A
----------------
G
--
A
K
K
E
V
I
N
Q
R
V
N
Q
----------
V
A
E
V
L
-
Q
L
A
H
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
-
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
----
E
L
Y
H
Y
---
P
A
---------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.54
30%
-103
- C1 -
1GAJ
7
LIVG_METJA
A:
[5-256]
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
-
E
----
F
K
A
L
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
K
D
I
T
N
K
E
P
A
--
E
--
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
E
I
N
P
----
G
E
-----
S
----------
P
--
L
N
S
L
F
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
-
K
L
S
H
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N
P
K
M
I
V
M
D
Q
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
-
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
S
D
---
P
K
V
V
E
I
--
Y
-----------------------
I
G
-------------------------------------------------------------------------
57
HHSearch
64.61
25%
-112
- C1 -
1V43
-
?
A:
[10-240]
M
V
E
V
K
L
E
N
L
T
K
R
F
G
-
N
----
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
R
D
V
T
Y
L
P
P
-------
K
D
R
N
I
S
M
V
F
Q
------
H
M
T
V
Y
E
N
I
A
--
F
P
L
------
K
-----
K
-------------
F
P
K
D
E
I
D
K
R
V
R
W
----------
A
A
E
L
L
-
Q
I
E
E
L
L
N
R
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
-
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
----
E
V
Y
L
R
---
P
----------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
64.29
27%
-105
- C1 -
2IT1
-
?
A:
[1-236]
M
V
E
I
K
L
E
N
I
V
K
K
F
G
-
N
----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
K
D
V
T
E
L
P
P
K
--
D
--
R
---
N
V
G
L
V
F
Q
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
--
F
P
L
E
L
R
KA
P
R
-----
E
----------
E
--
I
D
K
K
V
R
E
V
A
---------------
K
M
L
-
H
I
D
K
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
-
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
----
E
V
Y
Y
K
---
P
K
Y
K
F
V
G
G
F
-----------------------
L
G
N
------------------------------------------------------------------------
4
PsiBlast_PDB
60.89
65%
-8
- C1 -
4P31
2
LPTB_ECOLI
A:
[1-234]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
P
L
H
--
A
--
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
--
A
V
L
Q
----
I
R
-----
D
----------
D
--
L
S
A
E
Q
R
E
D
R
A
N
E
----------
L
M
E
E
F
-
H
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
-
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
----
E
I
L
Q
D
---
E
H
V
K
R
V
--
Y
-----------------------
L
--------------------------------------------------------------------------