@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4535: (2016-02-28 )
MNEADYLRLLTRQAEQANDFLSNARKWDRERWVCQRFLEALNVPYRQEDFAAPGEQPPDVLFKGAGFEVFFVLDEGRRLNEEWREELTRRRQAVSLRQLIRREERPQRIAAAELQARLAPTLRKKAHNYSERGIDHGELDLLAFVNLKRAVPDFNTPFPPPTEYLRQGWRSLSMVGPTFARVLFAHSGAPEFLRANLGRSILFDAGVGL
Atome Classification :
(20 SA)
-------------------------.........10-........20........30.--.......40.---.......50.....--..---------------.60....------....70.....--...80-------......-------------...90-----...-------.----....100-----.....--..110.......120-.....-----..130-..-----......140..--..----....150........160..---------.-..----..170.......180.......--------190.....--..200.......----------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------M
N
E
A
D
Y
L
R
L
L
T
-
R
Q
A
E
Q
A
N
D
F
L
S
N
A
R
K
W
D
R
E
R
W
--
V
C
Q
R
F
L
E
A
LN---VPYRQEDFAAPGEQ--PP---------------D
V
L
F
KGA------G
F
E
V
F
F
V
LDEG--RRL
N
--------
E
E
W
R
E
E
-------------
L
T
R
R
R
-----
Q
A
V
-------
S
----
L
R
Q
L
I
R
R
-----
E
ER
P
Q
--
R
I
A
A
A
E
L
Q
A
R
L
A
P
T
L
-
R
K
K
AH-----NYSE--RG-----IDHG
E
L
D
L
-
L
A
--
F
V
----
N
L
K
R
A-VPDFNTPFPP
P
T
E
Y
---------
L
-
R
Q
----
G
W
R
S
LSMV
G
P
T
F
A
R
V
L
F
AHSG
A
--------
P
E
F
L
R
A
NL--GR
S
I
L
FDAGVGL----------------------------------------------------------------
1
PsiBlast_PDB
96.35
99%
-89
- C3 -
1Y0K
-
?
A:
[2-209]
--------------------------
N
E
A
D
Y
L
R
L
L
T
-
R
Q
A
E
Q
A
N
D
F
L
S
N
A
R
K
W
D
R
E
R
W
--
V
C
Q
R
F
L
E
A
L
N
---
V
P
Y
R
Q
E
D
F
A
A
P
G
E
Q
--
P
P
---------------
D
V
L
F
K
G
A
------
G
F
E
V
F
F
V
L
D
E
-------------------------------------------------------------------------
R
P
Q
--
R
I
A
A
A
E
L
Q
A
R
L
A
P
T
L
-
R
K
K
A
H
-----
N
Y
S
E
--
R
G
-----
I
D
H
G
E
L
D
L
-
L
A
--
F
V
----
N
L
K
R
A
-
V
P
D
F
N
T
P
F
P
P
P
T
E
Y
---------
L
-
R
Q
----
G
W
R
S
L
S
M
V
G
P
T
F
A
R
V
L
F
A
H
S
G
A
--------
P
E
F
L
R
A
N
L
--
G
R
S
I
L
F
D
A
G
V
G
L
----------------------------------------------------------------
14
Fugue
96.32
100%
-89
- C3 -
1Y0K
-
?
A:
[2-209]
--------------------------
N
E
A
D
Y
L
R
L
L
T
-
R
Q
A
E
Q
A
N
D
F
L
S
N
A
R
K
W
D
R
E
R
W
--
V
C
Q
R
F
L
E
A
L
N
---
V
P
Y
R
Q
E
D
F
A
A
P
G
E
Q
--
P
P
---------------
D
V
L
F
K
G
A
------
G
F
E
V
F
F
V
L
D
E
-------------------------------------------------------------------------
R
P
Q
--
R
I
A
A
A
E
L
Q
A
R
L
A
P
T
L
-
R
K
K
A
H
-----
N
Y
S
E
--
R
G
-----
I
D
H
G
E
L
D
L
-
L
A
--
F
V
----
N
L
K
R
A
-
V
P
D
F
N
T
P
F
P
P
P
T
E
Y
---------
L
-
R
Q
----
G
W
R
S
L
S
M
V
G
P
T
F
A
R
V
L
F
A
H
S
G
A
--------
P
E
F
L
R
A
N
L
--
G
R
S
I
L
F
D
A
G
V
G
L
----------------------------------------------------------------
4
HHSearch
76.75
100%
4
- C3 -
1Y0K
-
?
A:
[1-209]
-------------------------
M
N
E
A
D
Y
L
R
L
L
T
-
R
Q
A
E
Q
A
N
D
F
L
S
N
A
R
K
W
D
R
E
R
W
--
V
C
Q
R
F
L
E
A
L
N
---
V
P
Y
R
Q
E
D
F
A
A
P
G
E
Q
--
P
P
---------------
D
V
L
F
K
G
A
------
G
F
E
V
F
F
V
L
D
E
-------------------------------------------------------------------------
R
P
Q
--
R
I
A
A
A
E
L
Q
A
R
L
A
P
T
L
-
R
K
K
A
H
-----
N
Y
S
E
--
R
G
-----
I
D
H
G
E
L
D
L
-
L
A
--
F
V
----
N
L
K
R
A
-
V
P
D
F
N
T
P
F
P
P
P
T
E
Y
---------
L
-
R
Q
----
G
W
R
S
L
S
M
V
G
P
T
F
A
R
V
L
F
A
H
S
G
A
--------
P
E
F
L
R
A
N
L
--
G
R
S
I
L
F
D
A
G
V
G
L
----------------------------------------------------------------
15
Fugue
52.99
20%
-33
- C3 -
1KC6
3
T2C2_HAEIF
A:
[1-257]
-----------------SFIKPI
Y
Q
D
I
N
S
I
L
I
G
Q
K
V
-
K
R
P
A
A
G
E
P
F
E
K
L
V
Y
K
F
L
K
E
N
L
SD
L
T
F
K
Q
Y
E
Y
L
N
---
D
L
F
M
K
N
P
-
A
I
I
G
H
E
--
A
R
---------------
Y
K
L
F
N
S
P
------
T
L
--
L
F
L
L
S
R
G
--
K
A
A
T
--------
E
N
W
S
I
E
N
L
F
E
E
KQNDTAD
I
L
L
V
K
D
-----
Q
F
Y
-------
E
----
L
L
D
V
K
T
R
NISKS
A
Q
A
P
N
--
I
I
S
A
Y
K
L
A
Q
T
C
A
K
M
I
-
D
N
K
E
F
DL
F
D
I
N
Y
L
E
V
D
W
E
-----
L
N
G
E
D
L
V
C
-
V
S
T
S
F
A
----
E
L
F
K
S
-
E
P
S
E
L
Y
I
N
W
A
A
A
M
Q
---------
I
-
Q
F
----
H
V
R
D
L
D
Q
-
G
F
N
G
T
R
E
E
W
A
K
S
Y
L
--------
K
H
F
V
T
Q
A
E
--
Q
R
A
I
S
M
I
D
K
F
V
K
PFKKYIL---------------------------------------------------------
17
Fugue
50.94
15%
-27
- C3 -
1NI9
2
GLPX_ECOLI
A:
[1-327]
--------------------GHMRR
E
L
A
I
E
F
S
R
V
T
E
-
S
A
A
L
A
G
Y
K
W
L
G
R
G
D
K
N
T
A
D
G
A
--
A
V
N
A
M
R
I
M
L
N
Q
--
V
N
I
D
G
T
I
V
I
G
E
G
E
A
--
P
M
LYIG
E
K
V
G
TGR
G
D
A
V
D
I
A
V
D
P
I
EGTQAN
A
L
A
V
L
A
V
G
D
K
G
CF
L
N
A
P
--------
D
M
Y
M
E
K
-------------
L
I
V
G
P
-----
G
A
K
GTIDLNL
P
----
L
A
D
N
L
R
N
-----
V
A
A
A
L
--
G
K
P
L
S
E
L
T
V
T
I
L
A
K
H
-
D
A
V
I
A
-----
E
M
Q
Q
--
L
G
V
R
V
F
A
I
P
D
G
D
V
A
A
-
S
I
--
L
T
----
C
M
P
D
S
-
E
V
D
V
L
Y
G
I
G
G
A
P
E
G
---------
V
-
V
S
----
A
A
V
I
R
A
L
D
G
D
M
N
G
R
L
L
A
G
I
E
A
G
--------
K
V
L
R
L
G
D
M
A
R
S
D
N
V
I
F
S
A
T
G
I
T
KGDLLE
G
I
S
R
K
GN
I
A
T
T
E
T
L
L
I
R
GKSR
T
I
R
R
I
Q
S
I
H
Y
L
D-------------------------
18
Fugue
43.97
11%
-22
- C3 -
4DHX
-
GANP_HUMAN
A:
[1162-1233]
-----------------------------------------------------------------------------------------------------------------------
L
V
L
S
E
L
S
Q
G
L
A
--
V
E
L
M
--------
E
R
V
M
M
E
-------------
F
V
R
E
T
-----
C
S
Q
-------
E
----
L
K
N
A
V
E
T
-----
D
Q
R
V
R
V
A
R
C
C
E
D
V
C
A
H
L
V
D
L
F
L
-
V
E
E
I
F
-----
Q
T
A
K
--
E
T
-----
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
42.41
13%
-46
- C1 -
4OQ2
1
?
A:
[4-300]
-----------------------------
H
H
H
H
H
E
F
M
S
K
T
D
Y
I
L
R
A
L
S
K
I
S
H
K
R
W
E
H
Y
--
I
I
N
R
V
V
H
T
L
D
DPD
I
E
F
V
C
Q
Q
C
I
R
K
E
G
H
--
L
G
K
I
Y
L
A
----------
D
L
L
F
--
P
------
Q
L
N
L
Y
L
E
I
D
E
A
--
H
H
D
S
--------
N
D
A
R
K
A
-------------
D
A
V
R
R
-----
L
D
I
-------
V
EATG
F
Q
E
E
R
I
P
-----
A
S
N
I
T
--
L
S
E
V
N
K
L
V
D
E
F
V
R
L
V
-
K
D
K
K
E
-----
E
L
E
N
--
Q
G
LFFR-
W
D
Y
D
E
R
Y
S
-
A
K
--
K
H
----
I
N
T
G
Y
M
A
V
G
P
N
S
V
F
R
Y
H
R
D
A
---------
L
-
Q
C
F
GYR
R
E
G
H
H
Q
S
G
G
W
A
L
P
A
E
V
A
Q
S
I
G
L
T
G
R
V
M
V
W
F
P
R
L
Y
E
A
G
E
--
W
K
N
A
L
S
A
D
G
N
K
I
T
E
Q
S
LNATRNYQETWDYRIVM
A
H
S
R
D
ELN
R
T
L
Y
R
F
L
G
V
F
A
I
DVDKSSDE
V
K
V
F
S
R
VYS
R
V
N
V
YR
20
Fugue
41.00
11%
-27
- C2 -
1A4U
-
ADH_DROLE
A:
[1-254]
MDLTN
K
N
V
I
F
V
AALGGI
G
L
D
T
S
R
E
L
V
K
R
N
L
K
N
F
V
I
L
-
D
R
V
E
N
P
T
A
L
A
E
L
K
A
I
N
P
K
V
N
I
--
T
F
H
T
Y
D
V
T
V
P
---
V
A
E
S
K
K
L
L
K
K
I
F
D
Q
L
K
T
V
---------------
D
I
L
I
N
G
A
------
G
I
L
D
D
H
Q
I
E
R
T
--
I
A
I
N
F
T
G
L
V
N
T
T
T
A
I
L
D
F
-------------
W
D
K
R
K
GGP
G
G
I
I
A
-------
N
----
I
C
S
V
T
G
F
-----
N
A
I
H
Q
--
V
P
V
Y
S
A
S
K
A
A
V
V
S
F
T
-
N
S
L
A
K
-----
L
A
P
I
--
T
G
-----
V
T
A
Y
S
I
N
P
G
I
T
--
R
T
----
P
L
V
H
T
-
F
N
S
W
L
D
V
E
P
R
V
A
E
L
---------
L
L
S
H
----
P
T
Q
T
S
E
Q
C
G
Q
N
F
V
K
A
I
E
A
N
K
N
G
--------
A
-
I
W
K
L
D
L
--
G
T
L
E
A
I
E
W
T
K
H
W
DSHI------------------------------------------------------------
19
Fugue
39.57
11%
12
- C3 -
1FE6
-
?
A:
[1-52]
-------------------------------------------------------------------------------------------------------------------------------------------------
G
S
I
I
N
-------------
E
T
A
D
D
-----
I
V
Y
-------
R
----
L
T
V
I
I
D
D
-----
R
Y
E
S
L
--
K
N
L
I
T
L
R
A
D
R
L
E
M
I
I
-
N
D
N
V
S
-----
T
I
L
A
--
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
38.69
16%
24
* C3 *
1Y66
7
?
A:
[3-52]
-------------------------------------------------------------------------------------------------------------------------------------------------
Q
W
S
E
E
-------------
V
E
R
K
L
-----
K
E
F
-------
V
----
R
R
H
Q
E
I
T
-----
Q
E
T
L
H
--
E
Y
A
Q
K
L
G
L
N
Q
Q
A
I
E
Q
-
F
F
R
E
F
-----
E
Q
R
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
34.70
30%
14
- C5 -
2JGD
-
ODO1_ECOLI
B:
[537-606]
--------------------------------------------------------------------------------------------------------------------------------------
L
N
--------
H
E
W
D
E
E
-------------
Y
P
N
K
V
-----
E
M
K
-------
R
----
L
Q
E
L
A
K
R
I
----
S
T
V
P
E
-----
A
V
E
M
Q
S
R
V
A
K
I
Y
A
D
R
Q
A
M
-----
A
A
G
E
--
K
L
-----
F
D
W
G
G
A
E
N
-
L
A
--
Y
A
----
T
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
32.99
36%
11
- C5 -
1Q77
-
Y178_AQUAE
A:
[24-82]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
-----
N
F
S
E
--
K
-------
L
G
A
E
L
D
I
-
L
A
--
V
L
E
D
V
Y
N
L
E
R
A
-
N
V
T
F
G
L
P
F
P
P
E
I
K
E
E
S
K
K
R
I
E
R
R
L
-
R
E
----
V
W
E
K
L
T
--------------------------------------------------------------------------------------------------------------
16
Fugue
32.77
10%
27
- C3 -
2LSE
-
?
A:
[1-101]
-------------------------------------------------------
M
Q
E
--
E
R
K
K
L
L
E
K
L
E
---
K
I
L
D
E
V
T
D
G
A
P
D
E
A
--
R
E
---------------
R
I
E
K
L
A
K
------
D
V
K
D
E
L
E
E
G
D
A
--
K
N
M
I
--------
E
K
F
R
D
E
-------------
M
E
Q
M
Y
-----
K
D
A
-------
P
----
N
A
V
M
E
Q
L
-----
L
E
E
I
E
--
K
L
L
K
K
A
G
S
L
V
P
R
G
S
Y
-
L
E
H
H
H
-----
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
28.66
27%
91
- C3 -
3EPO
-
THIC_CAUCR
A:
[290-311]
-------------------------
L
N
W
E
V
F
R
D
T
L
I
-
E
Q
C
E
Q
G
V
D
Y
F
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
28.52
24%
62
- C5 -
3VIQ
-
SFR1_SCHPO
A:
[90-110]
----------------------------------------------------
E
V
R
T
E
F
--
T
M
S
M
F
L
N
Q
F
G
---
V
P
V
H
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
26.06
10%
38
- C5 -
2WWB
-
SC61G_CANFA
B:
[6-44]
-----------------------------
Q
F
V
E
P
S
R
-
Q
F
V
K
D
S
I
R
L
V
K
R
C
T
K
P
D
R
K
E
F
--
Q
K
I
A
M
A
T
A
I
G
---
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
20.30
22%
8
* C4 *
3HSH
5
COIA1_HUMAN
A:
[26-48]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
--
F
V
----
A
E
Q
E
E
-
L
Y
V
R
-------------------
V
-
Q
N
----
G
F
R
K
V
Q
L
-------------------------------------------------------------------------------------------------------------
10
HHSearch
14.70
17%
35
- C4 -
3N3F
-
COFA1_HUMAN
A:
[24-46]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
--
Y
L
----
R
D
S
T
E
-
F
F
I
R
-------------------
V
-
R
D
----
G
W
K
K
L
Q
L
-------------------------------------------------------------------------------------------------------------
13
HHSearch
10.21
24%
193
- C4 -
2QNW
1
?
A:
[29-46]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
S
N
F
I--------
K
-
D
L
----
D
A
D
S
L
D
S
V
E
-----------------------------------------------------------------------------------------------------------
11
HHSearch
6.82
7%
232
* C5 *
2DU7
-
SEPS_METJA
A:
[474-487]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
----
N
I
R
Y
I
D
G
I
I
Y
K
L
--------------------------------------------------------------------------------------------------------