@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4616: (2016-02-29 )
MFKPFVGVALAALFAVSAVAHAEDAGPVVIKFSHVVSDDTPKGKGALLFKKLAEERLPGKVKVEVYPNSTLFGDADEIEALRANKVQMLATSLSKFEPYTKQLQVFDLPFLFDDLEALKRFQKRDKSRELLRSMAKHGIYGLAYWNNGMKQLSATRELHRPDDAKGLVFRIQPSSVLEAQFAMLGATAKQLSYAETLKAMQAGSVQGTENTWSNLAGQKIDSVQPYITETNHGALSYMLITSSAFWTGIPYQTRTELESIVDEVTLVVNKEAEALNQKEREHLLAAGKSRLVSLSAEEHEAWRNAMKPLWKNYEAQIGSDVLRAAQVVNRKR
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110....-...120....-...130..-...-..140.......150.......160.......170.......180..-.....190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.---......320.......330
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MFK
P
F
V
G
V
A
L
A
A
L
F
A
V
S
A
V
AHAEDAG
P
V
V
I
K
F
S
H
VVSDDTPKG
K
G
A
L
L
F
K
K
L
A
E
ERLP
G
K
V
K
V
E
V
YPNSTLFG
D
A
D
E
I
E
A
L
R
A
N
K
V
Q
M
L
A
T
S
L
S
KFE
P
Y
T
K
Q
L
Q
VFD
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
-
A
KH-G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
RELHRPDDAK
G
L
V
F
R
IQP
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
QAGSVQGTE
N
T
W
S
N
LAGQKIDSVQ
P
Y
I
TETNHG
A
L
S
Y
M
L
I
TSSAFWTGIPY
Q
T
R
T
E
L
E
S
I
V
D
E
V
T
L
VVN
K
E
A
E
AL
N
Q
K
E
R
E
H
L
L
A
AGK
S
R
L
V
S
LS
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
---
E
A
Q
I
G
S
D
V
L
R
A
A
Q
V
VNRKR
1
PsiBlast_PDB
99.02
100%
-63
- C3 -
4NF0
1
?
A:
[27-317]
--------------------------
P
V
V
I
K
F
S
H
V
V
S
D
D
T
P
K
G
K
G
A
L
L
F
K
K
L
A
E
E
R
L
P
G
K
V
K
V
E
V
Y
P
N
S
T
L
F
G
D
A
D
E
I
E
A
L
R
A
N
K
V
Q
M
L
A
T
S
L
S
K
F
E
P
Y
T
K
Q
L
Q
V
F
D
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
-
A
K
H
-
G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
R
E
L
H
R
P
D
D
A
K
G
L
V
F
R
I
Q
P
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
Q
A
G
S
V
Q
G
T
E
N
T
W
S
N
L
A
G
Q
K
I
D
S
V
Q
P
Y
I
T
E
T
N
H
G
A
L
S
Y
M
L
I
T
S
S
A
F
W
T
G
I
P
Y
Q
T
R
T
E
L
E
S
I
V
D
E
V
T
L
V
V
N
K
E
A
E
A
L
N
Q
K
E
R
E
H
L
L
A
A
G
K
S
R
L
V
S
L
S
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
---
E
A
Q
I
---------------
25
PsiBlast_CBE
98.69
100%
-58
- C3 -
4NF0
2
?
C:
[27-317]
--------------------------
P
V
V
I
K
F
S
H
V
V
S
D
D
T
P
K
G
K
G
A
L
L
F
K
K
L
A
E
E
R
L
P
G
K
V
K
V
E
V
Y
P
N
S
T
L
F
G
D
A
D
E
I
E
A
L
R
A
N
K
V
Q
M
L
A
T
S
L
S
K
F
E
P
Y
T
K
Q
L
Q
V
F
D
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
-
A
K
H
-
G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
R
E
L
H
R
P
D
D
A
K
G
L
V
F
R
I
Q
P
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
Q
A
G
S
V
Q
G
T
E
N
T
W
S
N
L
A
G
Q
K
I
D
S
V
Q
P
Y
I
T
E
T
N
H
G
A
L
S
Y
M
L
I
T
S
S
A
F
W
T
G
I
P
Y
Q
T
R
T
E
L
E
S
I
V
D
E
V
T
L
V
V
N
K
E
A
E
A
L
N
Q
K
E
R
E
H
L
L
A
A
G
K
S
R
L
V
S
L
S
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
---
E
A
Q
I
---------------
22
PsiBlast_CBE
98.17
100%
-60
- C3 -
4NF0
2
?
G:
[27-313]
--------------------------
P
V
V
I
K
F
S
H
V
V
S
D
D
T
P
K
G
K
G
A
L
L
F
K
K
L
A
E
E
R
L
P
G
K
V
K
V
E
V
Y
P
N
S
T
L
F
G
D
A
D
E
I
E
A
L
R
A
N
K
V
Q
M
L
A
T
S
L
S
K
F
E
P
Y
T
K
Q
L
Q
V
F
D
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
-
A
K
H
-
G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
R
E
L
H
R
P
D
D
A
K
G
L
V
F
R
I
Q
P
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
Q
A
G
S
V
Q
G
T
E
N
T
W
S
N
L
A
G
Q
K
I
D
S
V
Q
P
Y
I
T
E
T
N
H
G
A
L
S
Y
M
L
I
T
S
S
A
F
W
T
G
I
P
Y
Q
T
R
T
E
L
E
S
I
V
D
E
V
T
L
V
V
N
K
E
A
E
A
L
N
Q
K
E
R
E
H
L
L
A
A
G
K
S
R
L
V
S
L
S
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
----------------------
24
PsiBlast_CBE
98.01
100%
-59
- C3 -
4NF0
3
?
D:
[27-315]
--------------------------
P
V
V
I
K
F
S
H
V
V
S
D
D
T
P
K
G
K
G
A
L
L
F
K
K
L
A
E
E
R
L
P
G
K
V
K
V
E
V
Y
P
N
S
T
L
F
G
D
A
D
E
I
E
A
L
R
A
N
K
V
Q
M
L
A
T
S
L
S
K
F
E
P
Y
T
K
Q
L
Q
V
F
D
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
-
A
K
H
-
G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
R
E
L
H
R
P
D
D
A
K
G
L
V
F
R
I
Q
P
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
Q
A
G
S
V
Q
G
T
E
N
T
W
S
N
L
A
G
Q
K
I
D
S
V
Q
P
Y
I
T
E
T
N
H
G
A
L
S
Y
M
L
I
T
S
S
A
F
W
T
G
I
P
Y
Q
T
R
T
E
L
E
S
I
V
D
E
V
T
L
V
V
N
K
E
A
E
A
L
N
Q
K
E
R
E
H
L
L
A
A
G
K
S
R
L
V
S
L
S
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
---
E
A
-----------------
23
PsiBlast_CBE
97.52
100%
-59
- C3 -
4NF0
2
?
F:
[27-314]
--------------------------
P
V
V
I
K
F
S
H
V
V
S
D
D
T
P
K
G
K
G
A
L
L
F
K
K
L
A
E
E
R
L
P
G
K
V
K
V
E
V
Y
P
N
S
T
L
F
G
D
A
D
E
I
E
A
L
R
A
N
K
V
Q
M
L
A
T
S
L
S
K
F
E
P
Y
T
K
Q
L
Q
V
F
D
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
-
A
K
H
-
G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
R
E
L
H
R
P
D
D
A
K
G
L
V
F
R
I
Q
P
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
Q
A
G
S
V
Q
G
T
E
N
T
W
S
N
L
A
G
Q
K
I
D
S
V
Q
P
Y
I
T
E
T
N
H
G
A
L
S
Y
M
L
I
T
S
S
A
F
W
T
G
I
P
Y
Q
T
R
T
E
L
E
S
I
V
D
E
V
T
L
V
V
N
K
E
A
E
A
L
N
Q
K
E
R
E
H
L
L
A
A
G
K
S
R
L
V
S
L
S
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
---
E
------------------
26
PsiBlast_CBE
92.39
100%
-53
- C3 -
4NF0
3
?
B:
[27-317]
--------------------------
P
V
V
I
K
F
S
H
V
V
S
D
D
T
P
K
G
K
G
A
L
L
F
-------------
V
E
V
Y
P
N
S
T
L
F
G
D
A
D
E
I
E
A
L
R
A
N
K
V
Q
M
L
A
T
S
L
S
K
F
E
P
Y
T
K
Q
L
Q
V
F
D
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
-
A
K
H
-
G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
R
E
L
H
R
P
D
D
A
K
G
L
V
F
R
I
Q
P
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
Q
A
G
S
V
Q
G
T
E
N
T
W
S
N
L
A
G
Q
K
I
D
S
V
Q
P
Y
I
T
E
T
N
H
G
A
L
S
Y
M
L
I
T
S
S
A
F
W
T
G
-----
R
T
E
L
E
S
I
V
D
E
V
T
L
V
V
N
K
E
A
E
A
L
N
Q
K
E
R
E
H
L
L
A
A
G
K
S
R
L
V
S
L
S
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
---
E
A
Q
I
---------------
21
PsiBlast_CBE
89.55
100%
-50
- C3 -
4NF0
1
?
H:
[32-315]
-------------------------------
F
S
H
V
V
S
D
D
T
P
K
G
K
G
A
L
L
F
K
K
L
----------
V
E
V
Y
P
N
S
T
L
F
G
D
A
D
E
I
E
A
-------
M
L
A
T
S
L
S
K
F
E
P
Y
T
K
Q
L
Q
V
F
D
L
P
F
L
F
D
D
L
E
-
A
L
K
R
F
Q
K
R
D
K
-
S
R
E
L
L
R
S
M
--
K
H
-
G
I
Y
G
L
A
Y
W
N
N
G
M
K
Q
L
S
A
T
R
E
L
H
R
P
D
D
A
K
G
L
V
F
R
I
Q
P
S
S
V
L
E
A
Q
F
A
M
L
-
G
A
T
A
K
Q
L
S
Y
A
E
T
L
K
A
M
Q
A
G
S
V
Q
G
T
E
N
T
W
S
N
L
A
G
Q
K
I
D
S
V
Q
P
Y
I
T
E
T
N
H
G
A
L
S
Y
M
L
I
T
S
S
A
F
W
T
G
I
-----
T
E
L
E
S
I
V
D
E
V
T
L
V
V
N
K
E
A
E
A
L
N
Q
K
E
R
E
H
L
L
A
A
G
K
S
R
L
V
S
L
S
A
E
E
H
E
A
W
R
N
A
M
K
P
L
W
K
N
Y
---
E
A
-----------------
6
PsiBlast_PDB
73.12
22%
-44
- C3 -
3B50
1
SIAP_HAEIN
A:
[5-307]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
V
K
Q
T
G
Q
K
G
E
S
A
L
K
Q
I
E
A
I
N
P
K
-
4
PsiBlast_PDB
72.39
25%
-58
- C3 -
4MAG
1
?
A:
[28-293]
-----------------------------------------------------
E
E
M
S
Q
G
E
I
K
L
A
L
Y
P
S
A
Q
L
G
D
D
R
A
M
L
Q
Q
L
T
L
G
D
L
D
I
T
Y
A
E
F
G
R
M
G
L
W
I
P
R
A
E
A
V
M
L
P
Y
V
A
K
D
F
D
-
H
L
R
R
M
F
E
S
D
F
-
G
Q
G
V
R
D
E
M
L
Q
K
F
-
N
W
R
A
L
D
T
W
Y
N
G
T
R
E
T
T
S
N
R
P
L
N
S
I
E
D
F
K
G
L
K
L
R
V
-
P
N
A
K
Q
N
L
N
Y
A
K
L
S
G
A
S
P
T
P
M
S
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
P
T
I
K
T
M
K
F
Y
E
V
Q
K
N
L
A
M
T
H
H
I
V
N
D
Q
M
V
I
I
S
E
S
T
W
Q
K
L
---
S
D
T
D
K
D
I
I
Q
K
A
V
Q
K
V
G
D
A
H
T
Q
T
V
K
T
Q
E
A
E
-
L
V
S
F
F
K
S
E
G
I
N
V
T
Y
P
D
L
E
P
F
R
E
A
M
Q
P
L
Y
K
E
F
---
D
S
N
I
G
Q
P
I
V
----------
8
PsiBlast_PDB
71.81
22%
-47
- C3 -
2WYK
3
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
11
PsiBlast_PDB
71.73
22%
-55
- C3 -
2CEY
2
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
10
PsiBlast_PDB
71.32
22%
-53
- C3 -
2CEX
-
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
15
PsiBlast_PDB
71.24
23%
-54
- C3 -
2XA5
1
SIAP_HAEIN
A:
[19-291]
-------------------------------------------
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
12
PsiBlast_PDB
71.12
22%
-46
- C3 -
2XWV
1
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
17
PsiBlast_PDB
71.06
22%
-48
- C3 -
2XWI
1
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
K
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
7
PsiBlast_PDB
71.06
22%
-48
- C3 -
2XXK
1
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
D
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
13
PsiBlast_PDB
70.80
23%
-54
- C3 -
2WX9
1
SIAP_HAEIN
A:
[19-291]
-------------------------------------------
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
19
PsiBlast_PDB
70.71
22%
-47
- C3 -
2XWK
1
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
A
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------
16
PsiBlast_PDB
70.63
24%
-47
- C3 -
4MMP
1
?
A:
[6-287]
-----------------------------
L
K
F
G
M
V
A
G
P
S
S
N
E
Y
K
A
V
E
F
F
A
K
E
V
K
E
K
S
N
G
K
I
D
V
A
I
F
P
S
S
Q
L
G
D
D
R
V
M
I
K
Q
L
K
D
G
A
L
D
F
T
L
G
E
S
A
R
F
Q
I
Y
F
P
E
A
E
V
F
A
L
P
Y
M
I
P
N
F
E
-
T
S
K
K
A
L
L
D
T
K
F
G
Q
G
L
L
K
K
I
-
D
K
E
L
N
V
Q
V
L
S
V
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
E
D
M
K
G
L
K
L
R
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
A
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
S
V
D
G
Q
E
N
P
L
P
T
I
Q
A
Q
K
F
Y
E
V
Q
K
Y
L
A
L
T
N
H
I
L
N
D
Q
L
Y
L
I
S
N
D
T
L
A
D
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
A
K
A
A
E
Y
H
T
K
L
F
V
D
G
E
N
S
L
V
E
F
F
K
S
Q
G
V
T
V
T
Q
P
D
L
K
P
F
K
A
A
L
T
P
Y
Y
D
E
Y
----------------------
18
PsiBlast_PDB
70.37
22%
-48
- C3 -
2XWO
1
SIAP_HAEIN
A:
[5-291]
-----------------------------
L
K
F
G
M
N
A
G
T
S
S
N
E
Y
K
A
A
E
M
F
A
K
E
V
K
E
K
S
Q
G
K
I
E
I
S
L
Y
P
S
S
Q
L
G
D
D
R
A
M
L
K
Q
L
K
D
G
S
L
D
F
T
F
A
E
S
A
R
F
Q
L
F
Y
P
E
A
A
V
F
A
L
P
Y
V
I
S
N
Y
N
V
A
Q
K
A
L
F
D
T
E
F
-
G
K
D
L
I
K
K
M
-
D
K
D
L
G
V
T
L
L
S
Q
A
Y
N
G
T
R
Q
T
T
S
N
R
A
I
N
S
I
A
D
M
K
G
L
K
L
E
V
P
N
A
A
T
N
L
A
Y
A
K
Y
V
-
G
A
S
P
T
P
M
A
F
S
E
V
Y
L
A
L
Q
T
N
A
V
D
G
Q
E
N
P
L
A
A
V
Q
A
Q
K
F
Y
E
V
Q
K
F
L
A
M
T
N
H
I
L
N
D
Q
L
Y
L
V
S
N
E
T
Y
K
E
L
P
----
E
D
L
Q
K
V
V
K
D
A
A
E
N
A
A
K
Y
H
T
K
L
F
V
D
G
E
K
D
L
V
T
F
F
E
K
Q
G
V
K
I
T
H
P
D
L
V
P
F
K
E
S
M
K
P
Y
Y
A
E
F
---
V
K
Q
T
G
--------------