@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4832: (2016-03-01 )
MNEQIGNGVALVTGASSGIGATYAEHLARRGHDLLLVARDRQRLEALADRLRQAHGVRVEILRADLSERDDRLRVERRLRDDASIALLVNNAGVAMNGPLADADMDRAERMIALNVVALTRLAAGAAEGFRRRGGGAIVNLGSVVALAPELFNAVYSATKAYVLSLSQSLQHELAGSGVYVQAVLPGVTRTEIWERSGTGIAGIPAEMVMEVEDLVEAALVGFDRREAVTIPSLPDAADWQALMTARARLAPNLSRQRPAERYLG
Atome Classification :
(28 SA)
.........10........20........30.....--------...40........50-..-......60.......-.70........80-.--....-...90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200---------------.........210.......220.......230.......240.......250.......260...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNEQIGN
G
V
A
L
V
TGASSGI
G
A
T
Y
A
E
H
L
A
RRG
H
D
L
L
L
--------
V
AR
D
R
Q
R
L
E
A
L
A
D
R
L
-
R
Q
-AHG
V
R
V
E
I
L
R
A
D
L
SE-
R
D
D
R
L
R
V
E
R
R
LRD-D--A
S
I
A
-
L
L
V
NNAGVAMNGPLAD
A
D
M
D
R
A
E
R
M
I
A
L
N
V
V
A
L
T
R
L
A
A
G
A
A
E
G
F
R
RRGG
G
A
I
V
NL
G
S
V
V
A
L
A
P
E
L
F
N
A
V
Y
S
A
T
K
A
Y
V
L
S
L
S
Q
S
L
Q
H
E
LAGS
G
V
Y
V
Q
AVLPGV
T
R
T
E
I
WERSGTG-----------------IAGI
P
A
E
M
V
M
E
V
E
D
L
V
E
A
A
L
VGFDRREAVTIPSLP
D
A
A
D
W
Q
A
L
M
T
A
R
A
R
LAPNLSRQR
P
A
E
RYLG
27
PsiBlast_CBE
96.97
58%
-118
- C2 -
4BMV
1
?
D:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
26
PsiBlast_CBE
96.74
58%
-119
- C2 -
4BMV
1
?
E:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
29
PsiBlast_CBE
96.59
58%
-118
- C2 -
4BMV
1
?
B:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
28
PsiBlast_CBE
96.57
58%
-118
- C2 -
4BMV
1
?
C:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
25
PsiBlast_CBE
96.55
58%
-118
- C2 -
4BMV
1
?
F:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
22
PsiBlast_CBE
96.50
58%
-118
- C2 -
4BMV
1
?
I:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
-
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
21
PsiBlast_CBE
96.40
58%
-118
- C2 -
4BMV
1
?
J:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
-
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
24
PsiBlast_CBE
96.34
58%
-117
- C2 -
4BMV
1
?
G:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
1
PsiBlast_PDB
96.11
58%
-118
- C2 -
4BMV
1
?
A:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
23
PsiBlast_CBE
96.01
58%
-117
- C2 -
4BMV
1
?
H:
[8-258]
----------
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
--------
V
A
R
D
K
V
R
L
D
A
L
A
A
R
L
-
R
D
-
E
S
G
V
A
V
E
A
L
Q
A
D
L
T
R
-
P
A
D
L
A
A
V
E
I
R
L
R
E
-
D
--
A
R
I
G
-
I
L
I
N
N
A
G
M
A
Q
S
G
G
F
V
Q
Q
T
A
E
G
I
E
R
L
I
T
L
N
T
T
A
L
T
R
L
A
A
A
V
A
P
R
F
V
Q
S
G
T
G
A
I
V
N
I
G
S
V
V
G
F
A
P
E
F
G
M
S
I
Y
G
A
T
K
A
F
V
L
F
L
S
Q
G
L
N
L
E
L
S
P
S
G
I
Y
V
Q
A
V
L
P
A
A
T
R
T
E
I
W
G
R
A
G
I
D
-----------------
V
N
T
L
P
E
--
V
M
E
V
D
E
L
V
D
A
A
L
V
G
F
D
R
R
E
L
V
T
I
P
P
L
H
V
A
A
R
W
D
A
L
D
G
A
R
Q
G
L
M
S
D
I
R
Q
A
Q
A
A
D
R
Y
--
116
HHSearch
66.97
32%
-97
- C2 -
3AI3
3
?
A:
[1-244]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
S
F
--
G
G
A
D
-
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
A
K
E
L
T
K
DNGGD
W
K
G
Y
L
Q
S
V
A
D
E
H
A
P
I
K
R
F
A
S
P
E
E
L
A
N
F
F
V
F
L
C
S
E
R
---------------------------------------
37
PsiBlast_CBE
62.83
34%
-97
- C2 -
3AI3
4
?
G:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
3
PsiBlast_PDB
62.59
34%
-100
- C2 -
3AI2
1
?
A:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
38
PsiBlast_CBE
62.48
34%
-95
- C2 -
3AI3
3
?
E:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
35
PsiBlast_CBE
62.46
34%
-97
- C2 -
3AI2
1
?
C:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
30
PsiBlast_CBE
62.01
34%
-98
- C2 -
3AI2
1
?
H:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
39
PsiBlast_CBE
61.79
34%
-97
- C2 -
3AI3
2
?
C:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
31
PsiBlast_CBE
61.78
34%
-99
- C2 -
3AI2
1
?
G:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
2
PsiBlast_PDB
61.48
34%
-101
- C2 -
3AI1
-
?
A:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
4
PsiBlast_PDB
61.40
34%
-96
- C2 -
3AI3
3
?
A:
[1-198]
M
D
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
--------
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
-
K
F
G
V
R
V
L
E
V
A
V
D
V
A
T
-
P
E
G
V
D
A
V
V
E
S
V
R
S
-
S
--
F
G
G
A
D
I
L
V
N
N
A
G
T
G
S
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
R
G
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
I
K
T
-------------------------------------------------------------------------------------
83
PsiBlast_CBE
53.59
31%
-102
- C2 -
3RRO
13
FABG_VIBCH
B:
[14-195]
--------
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
--------
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
N
-
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
-
A
-----
V
L
K
A
I
T
D
-
E
F-
G
G
V
D
-
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
-----------------------------------------------------------------------------------------
84
PsiBlast_CBE
52.51
31%
-101
- C2 -
3RRO
11
FABG_VIBCH
A:
[14-195]
--------
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
--------
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
N
-
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
-
A
-----
V
L
K
A
I
T
D
-
E
F-
G
G
V
D
-
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
-----------------------------------------------------------------------------------------
44
PsiBlast_CBE
49.15
31%
-85
- C2 -
3VDQ
4
?
C:
[7-195]
---------
A
V
V
T
G
S
T
S
G
I
G
L
A
M
A
T
E
L
A
K
A
G
A
D
V
V
I
NGFGQPED
I
E
R
E
R
S
T
L
E
S
---------
K
F
G
V
K
A
Y
Y
L
N
A
D
L
S
D
A
Q
A
T
R
D
F
I
A
K
A
A
E
A
-
L
--
G
G
L
D
-
I
L
V
N
N
A
G
I
Q
H
T
A
P
I
E
E
F
P
V
D
K
W
N
A
I
I
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
I
M
Q
K
Q
G
W
G
R
I
I
N
I
A
S
A
H
G
L
V
A
S
V
N
K
S
A
Y
V
A
A
K
H
G
V
V
G
L
T
K
V
T
A
L
E
N
A
G
K
G
I
T
C
N
A
I
C
P
G
W
V
R
T
P
L
V
E
K
--------------------------------------------------------------------------------------
43
PsiBlast_CBE
46.84
31%
-81
- C2 -
3VDQ
4
?
D:
[7-195]
---------
A
V
V
T
G
S
T
S
G
I
G
L
A
M
A
T
E
L
A
K
A
G
A
D
V
V
I
NGFGQPED
I
E
R
E
R
S
T
L
E
S
---------
K
F
G
V
K
A
Y
Y
L
N
A
D
L
S
D
A
Q
A
T
R
D
F
I
A
K
A
A
E
A
-
L
--
G
G
L
D
-
I
L
V
N
N
A
G
I
Q
H
T
A
P
I
E
E
F
P
V
D
K
W
N
A
I
I
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
I
M
Q
K
Q
G
W
G
R
I
I
N
I
A
S
A
H
G
L
V
A
S
V
N
K
S
A
Y
V
A
A
K
H
G
V
V
G
L
T
K
V
T
A
L
E
N
A
G
K
G
I
T
C
N
A
I
C
P
G
W
V
R
T
P
L
V
E
K
--------------------------------------------------------------------------------------
77
PsiBlast_CBE
45.98
32%
-90
- C2 -
3V1U
3
?
A:
[223-408]
--------
V
A
I
V
T
G
A
A
R
G
I
G
A
T
I
A
E
V
F
A
R
D
G
A
H
V
V
A
--------
I
-----
D
V
E
S
A
A
E
N
L
-
A
E
T
A
S
K
V
G
G
T
A
L
W
L
D
V
T
A
-
D
D
A
V
D
K
I
S
E
H
L
R
D
-
H
HG
G
K
A
D
-
I
L
V
N
N
A
G
I
T
R
D
K
L
L
A
N
M
D
D
A
R
W
D
A
V
L
A
V
N
L
L
A
P
L
R
L
T
E
G
L
V
G
N
G
S
I
G
E
G
G
R
V
I
G
L
S
S
I
A
G
I
A
G
N
R
G
Q
T
N
Y
A
T
T
K
A
G
M
I
G
I
T
Q
A
L
A
P
G
L
A
A
K
G
I
T
I
N
A
V
A
P
G
F
I
E
T
Q
M
-----------------------------------------------------------------------------------------
7
PsiBlast_PDB
45.54
31%
-83
- C2 -
3VDR
4
?
A:
[7-195]
---------
A
V
V
T
G
S
T
S
G
I
G
L
A
M
A
T
E
L
A
K
A
G
A
D
V
V
I
N
G
F
G
Q
P
E
D
I
E
R
E
R
S
T
L
E
S
---------
K
F
G
V
K
A
Y
Y
L
N
A
D
L
S
D
A
Q
A
T
R
D
F
I
A
K
A
A
E
A
-
L
--
G
G
L
D
-
I
L
V
N
N
A
G
I
Q
H
T
A
P
I
E
E
F
P
V
D
K
W
N
A
I
I
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
I
M
Q
K
Q
G
W
G
R
I
I
N
I
A
S
A
H
G
L
V
A
S
V
N
K
S
A
Y
V
A
A
K
H
G
V
V
G
L
T
K
V
T
A
L
E
N
A
G
K
G
I
T
C
N
A
I
C
P
G
W
V
R
T
P
L
V
E
K
--------------------------------------------------------------------------------------
42
PsiBlast_CBE
44.32
31%
-79
- C2 -
3VDR
4
?
B:
[7-195]
---------
A
V
V
T
G
S
T
S
G
I
G
L
A
M
A
T
E
L
A
K
A
G
A
D
V
V
I
NGFGQPED
I
E
R
E
R
S
T
L
E
S
---------
K
F
G
V
K
A
Y
Y
L
N
A
D
L
S
D
A
Q
A
T
R
D
F
I
A
K
A
A
E
A
-
L
--
G
G
L
D
-
I
L
V
N
N
A
G
I
Q
H
T
A
P
I
E
E
F
P
V
D
K
W
N
A
I
I
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
I
M
Q
K
Q
G
W
G
R
I
I
N
I
A
S
A
H
G
L
V
A
S
V
N
K
S
A
Y
V
A
A
K
H
G
V
V
G
L
T
K
V
T
A
L
E
N
A
G
K
G
I
T
C
N
A
I
C
P
G
W
V
R
T
P
L
V
E
K
--------------------------------------------------------------------------------------
40
PsiBlast_CBE
43.21
31%
-81
- C2 -
3VDR
4
?
D:
[7-195]
---------
A
V
V
T
G
S
T
S
G
I
G
L
A
M
A
T
E
L
A
K
A
G
A
D
V
V
I
NGFGQPED
I
E
R
E
R
S
T
L
E
S
---------
K
F
G
V
K
A
Y
Y
L
N
A
D
L
S
D
A
Q
A
T
R
D
F
I
A
K
A
A
E
A
-
L
--
G
G
L
D
-
I
L
V
N
N
A
G
I
Q
H
T
A
P
I
E
E
F
P
V
D
K
W
N
A
I
I
A
L
N
L
S
A
V
F
H
G
T
A
A
A
L
P
I
M
Q
K
Q
G
W
G
R
I
I
N
I
A
S
A
H
G
L
V
A
S
V
N
K
S
A
Y
V
A
A
K
H
G
V
V
G
L
T
K
V
T
A
L
E
N
A
G
K
G
I
T
C
N
A
I
C
P
G
W
V
R
T
P
L
V
E
K
--------------------------------------------------------------------------------------