@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA5060: (2016-03-04 )
MAGKKKSEKESSWIGEIEKYSRQIWLAGLGAYSKVSKDGSKLFETLVKDGEKAEKEAKSDVDAQVGAAKASARSAKSKVDEVRDRALGKWSELEEAFDKRLNSAISRLGVPSRNEVKELHSKVDTLTKQIEKLTGVSVKPAAKAAAKPAAKPAAKPAAKTAAAKPAAKPAAKAAAKPAAKPAAKKTAAKTAAAKPAAKPAAKPTAKAAAKPATKPAAKAAAKPAAKPAAAKPAAKPAAKPAAATAAKPAAKPAAKPAAKKPAAKKPAAKPAAAKPAAPAASSSAPAAPAATPAASAPAANAPATPSSQG
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------.........10........20..------......30........40.....----...50........60.---.......70....-....80...-.-....-------90........100------.......110........120.......130.......140.......150.......160.....------..170.......180.......190.......200......---.210.......220.......230---------........240.......250.......260.---......270-.........280.......290.......300.......----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------MAGKKKSE
K
E
S
S
W
I
G
E
I
E
K
Y
S
R
Q
------
I
W
L
A
GLG
A
Y
S
K
VSK
D
G
S
K
L
F
E
T
L
----
V
KD
G
E
K
A
E
K
E
A
KSDV
D
---
A
QVGAAKASA
R
S
A
-
K
S
K
V
D
E
V
R
D
-
R
-ALG
K
-------
W
S
E
L
E
E
A
F
D
K
R
L
N
------
S
A
I
S
RLGVP-
S
R
N
E
V
K
E
L
H
S
K
V
D
T
L
T
K
Q
I
E
K
L
TGVSVKPAAKAAAKPAAKPAAKPAAKTAAAKPAA------KP
A
A
KAAAKPAAKPA
A
K
K
T
AAKTAAAKPAAKPAAKPTAKAA---AKPATKP
A
A
KAAAKPAAKPAAAK----------PAAKPAAKPAAATAAKPAAKPAAKPAAKKPAA---KKPAAKP---AAAKPAAPAASSSAPAAPAATPAASAPAANAPATPSSQG----------------------------
26
Fugue
79.11
14%
40
- C2 -
1YVE
4
ILV5_SPIOL
I:
[237-524]
--------------------------------------------------------------------------------------------------------
L
E
Q
E
Y
K
S
D
I
F
G
E
R
-----
G
------
I
L
L
G
A
V
H
G
I
V
E
C
------
L
F
R
R
Y
----
T
E
S
G
M
S
E
D
L
A
Y
K
N
T
V
E
---
C
I
T
G
--
V
I
S
K
T
I
S
-
T
K
G
M
L
A
L
Y
N
-
S
---------------
L
S
E
E
G
K
K
D
F
Q
------
A
A
Y
S
A
S
Y
Y
P
-
S
M
D
I
L
Y
E
C
Y
E
D
V
A
S
---------
G
S
E
I
R
S
V
V
L
A
G
R
R
F
Y
E
K
E
G
L
P
A
F
P
M
G
K
I
D
Q
T
R
M
------
W
K
V
G
E
K
V
R
S
V
R
P
A
G
D
L
G
P
L
Y
P
F
T
A
G
V
Y
V
A
L
M
M
A
Q
I
E
I
L
R
K
K
GHS
Y
S
E
I
I
N
E
S
V
I
E
A
V
D
S
L
N
P
F
M
H
A
R
GVSFMVDNCS
T
T
A
R
L
G
S
R
K
W
A
P
R
F
D
Y
I
L
S
Q
Q
A
L
V
A
V
D
N
G
A
P
I
---
N
Q
D
L
I
S
N
---
F
L
S
D
P
V
H
E
A
I
G
V
C
A
Q
L
R
P
S
V
D
I
S
V
T
A
D
A
D
F
V
R
P
E
L
R
Q
A
-----------------------------
28
Fugue
65.79
14%
66
- C3 -
4K5Y
7
CRFR1_HUMAN (first)
A:
[13-423]
----------------------------------------H
Y
H
V
A
A
I
I
N
Y
L
G
H
C
I
S
L
V
A
L
L
V
A
F
V
L
F
L
R
ARSIRC
L
R
N
I
I
H
A
N
L
I
A
A
F
I
L
R
N
A
T
W
F
V
V
Q
L
T
M
S
P
E
V
H
Q
S
N
V
G
W
C
R
L
V
T
A
A
Y
N
Y
F
H
V
T
N
F
F
W
M
F
G
E
G
C
Y
L
H
T
A
I
V
L
T
N
I
F
E
M
L
----
R
I
D
-
E
G
L
R
L
K
I
Y
K
D
T
E
GY-
Y
T
I
G
I
G
H
L
L
T
K
S
P
S
L
S
V
A
K
S
E
L
D
-
K
-
A
I
G
R
NSNGVIT
K
D
E
A
E
K
L
F
N
Q
D
V
D
------
A
A
V
R
G
I
L
R
N
-
A
K
--
L
K
P
V
Y
D
S
L
D
A
V
R
R
S
A
L
I
N
M
V
F
Q
M
G
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
K
R
W
D
E
A
A
V
N
L
A
K
------
S
R
W
Y
N
Q
T
--
P
N
R
A
K
R
V
I
A
T
F
R
T
G
T
W
D
A
Y
D
R
L
R
A
W
M
F
I
C
I
G
W
---
G
V
P
F
P
I
I
V
A
W
A
I
G
K
L
Y
Y
D
N
E
K
C
W
----------
A
G
K
R
P
G
V
Y
T
D
Y
I
Y
Q
G
P
M
A
L
V
L
L
I
N
F
I
F
L
F
N
I
V
---
R
I
L
M
T
K
L
R--
A
S
T
T
S
E
T
I
Q
A
R
K
A
V
K
A
T
L
V
L
L
P
L
L
G
I
T
Y
M
L
A
F
V
N
E
V
S
R
V
V
F
I
Y
F
N
A
F
L
E
S
F
Q
G
F
F
V
S
V
F
A
C
F
L
N
S--
29
Fugue
60.64
13%
57
* C3 *
4DVZ
-
CAGA_HELPY
A:
[308-829]
L
M
G
S
H
N
GK
V
S
L
L
YAGDKHD
W
N
A
T
V
G
Y
K
DNVAT
L
I
N
V
H
M
KNG
S
G
L
V
I
A
G
G
EKGINN
P
S
F
Y
L
Y
K
E
D
QLTG
S
Q
R
A
L
S
Q
E
E
I
R
N
K
V
D
F
M
E
F
L
A
Q
N
NTKLDNLS
E
K
E
K
E
K
F
Q
N
E
I
E
D
F
Q
K
D
S
K
A
Y
L
D
A
------
L
G
N
D
R
I
A
F
V
S
K
K
D
T
K
H
S
A
L
I
T
E
F
N
NG
D
L
S
Y
T
L
K
D
-
Y
E
K
N
V
T
L
Q
G
S
L
K
H
D
G
V
M
F
V
D
Y
S
F
N
-
K
V
A
V
F
N
L
P
D
L
N
-
N
L
A
I
-------
T
S
F
V
R
R
N
L
E
N
K
L
T
A
K
GLS
L
Q
E
A
N
K
L
I
K
D
-
F
L
S
S
N
K
E
L
A
G
K
A
L
N
F
N
K
A
V
A
E
A
K
S
T
G
N
Y
D
E
V
K
K
A
Q
K
D
L
E
K
S
L
R
K
R
E
H
L
E
K
E
V
E
K
K
L
E
S
K
SGN
K
K
A
Q
A
N
S
Q
K
D
E
I
F
A
L
I
N
K
E
A
N
R
D
A
R
A
I
A
Y
T
Q
N
L
K
G
I
K
R
E
L
S
---
D
K
L
E
K
I
S
K
D
L
K
D
F
S
K
S
F
D
E
F
K
N
F
----------
S
K
A
E
E
T
L
K
A
L
K
G
S
V
K
D
L
G
I
N
P
E
W
I
S
K
V
E
N
L
N
A
---
A
L
N
E
F
K
N
GDF
S
K
V
T
Q
A
K
S
D
L
E
N
S
V
K
D
V
I
I
N
Q
K
V
T
D
K
V
D
N
L
N
Q
A
V
S
V
A
K
A
M
GDF
S
R
V
E
Q
V
L
A
D
L
K
N
F
S
K
E
Q
L
A
Q
Q
A
Q
K
24
Fugue
56.83
28%
-27
- C4 -
1LQ7
-
?
A:
[1-67]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
---
S
R
V
K
A
L
E
E
K
V
K
A
L
-
E
E
K
V
K
A
L
G
G
-
G
---
G
R
-------
I
E
E
L
K
K
K
W
E
E
-
L
K
------
K
K
I
E
E
L
G
---
G
G
G
E
V
K
K
V
E
E
E
V
K
K
L
E
E
E
I
K
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
55.23
12%
65
- C3 -
4TQL
-
?
A:
[9-239]
---------------------------------------------------------------------------------------------------------------------------------------------
Y
K
Q
M
V
Q
E
L
E
K
A
----
R
D
R
M
E
K
L
Y
K
E
M
V
E
L
I
Q
---
K
A
I
E
L
M
R
K
I
F
Q
E
V
-
K
Q
E
V
E
K
A
I
E
-
E
-
M
K
K
L
-------
Y
D
E
A
K
K
K
I
E
Q
M
I
Q
------
Q
I
K
Q
-------------------------------
G
G
D
K
Q
K
M
E
E
L
L
K
R
A
K
E
E
M
K
K
V
K
D
K
M
E
K
L
L
E
K
------
L
K
Q
I
M
Q
E
A
K
Q
K
M
E
K
L
L
K
Q
L
K
E
E
M
K
K
M
K
E
K
M
E
K
L
L
K
E
M
K
Q
R
M
---
E
E
V
K
K
K
M
--
D
D
E
L
L
E
K
I
K
K
N
I
D
D
----------
L
K
K
I
A
E
D
L
I
K
K
A
E
E
N
I
K
E
A
K
K
I
A
E
Q
L
V
K
R
A
K
Q
---
L
I
E
K
A
K
Q
---
V
A
E
E
L
I
K
K
I
L
Q
L
I
E
K
A
K
E
I
A
E
K
V
L
K
G
-----------------------------------------
2
PsiBlast_PDB
51.96
32%
85
- C4 -
4KE4
2
?
A:
[199-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
D
P
P
A
P
V
Y
P
H
V
E
Y
Q
P
A
P
A
M
----------
L
S
S
--------------
A
T
P
P
A
A
V
A
I
F
K
L
S
R
A
E
L
G
R
L
R
S
Q
V
P
---
A
R
E
R
E
G
A
P
R
F
S
T
Y
A
V
L
A
A
H
V
W
R
C
A
S
------------------------------------------
3
PsiBlast_PDB
47.58
32%
100
- C4 -
4KEC
1
?
A:
[199-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
D
P
P
A
P
V
Y
P
H
V
E
Y
Q
P
A
P
A
M
----------
L
-----------------
T
P
P
A
A
V
A
I
F
K
L
S
R
A
E
L
G
R
L
R
S
Q
V
P
---
A
R
E
R
E
G
A
P
R
F
S
T
Y
A
V
L
A
A
H
V
W
R
C
A
S
------------------------------------------
1
PsiBlast_PDB
47.57
36%
79
- C1 -
1OQY
-
RD23A_HUMAN
A:
[78-127]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
K
A
G
---
Q
G
T
S
A
P
P
---
E
A
S
P
T
A
A
P
E
S
S
T
S
F
P
P
A
P
T
S
G
M
S
H
P
P
P
A
A
R
E
D
K
S
P
S
E
E
-----------------------------
23
HHSearch
44.70
13%
40
* C4 *
3OKQ
-
BUD6_YEAST
A:
[572-625]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-
L
L
S
K
-------
V
D
D
L
Q
D
V
I
E
I
M
R
K
------
D
V
A
E
R
R
S
Q
P
-
A
K
K
K
L
E
T
V
S
K
D
L
E
N
A
Q
A
D
V
L
K
L
Q
E
F
I
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
43.74
17%
15
* C2 *
3U4Z
-
?
A:
[375-483]
--------------------------------------------------------------------------------------------------------------
T
L
L
I
S
E
V
L
K
T
S
K
Q
-------
Y
L
S
V
L
A
Q
V
V
D
I
Q
S
S
D
K
N
I
R
L
K
I
----
C
------
D
N
S
C
N
Q
E
L
K
---
V
V
I
---------
F
-
P
D
L
C
Y
E
W
R
D
-
K
F
S
I
N
K
-------
W
Y
Y
F
N
E
-
F
V
R
Q
I
Y
------
N
D
E
V
Q
L
K
N
N
-
I
H
S
S
I
K
E
S
D
D
Q
R
K
V
I
T
Y
N
Q
E
Q
G
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
42.51
22%
92
- C4 -
1GS9
-
APOE_HUMAN
A:
[107-161]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
E
D
V
R
G
-
R
-
L
V
Q
Y
-------
R
G
E
V
Q
A
M
L
G
Q
S
T
E
------
E
L
R
V
R
L
A
S
H
-
L
R
K
L
R
K
R
L
L
R
D
A
D
D
L
Q
K
R
L
A
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
40.32
40%
76
- C4 -
1QP6
-
?
A:
[1-35]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
-------
V
E
E
L
E
K
K
F
K
E
L
W
K
------
G
-------
P
-
R
R
G
E
I
E
E
L
H
K
K
F
H
E
L
I
K
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
39.73
21%
78
- C4 -
1NFN
-
APOE_HUMAN
A:
[108-159]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
D
V
C
G
-
R
-
L
V
Q
Y
-------
R
G
E
V
Q
A
M
L
G
Q
S
T
E
------
E
L
R
V
R
L
A
S
H
-
L
R
K
L
R
K
R
L
L
R
D
A
D
D
L
Q
K
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
38.85
14%
59
- C4 -
2L7B
-
APOE_HUMAN
A:
[131-181]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
R
V
-
R
-
L
A
S
H
-------
L
R
K
L
R
K
R
L
L
R
D
A
D
------
D
L
Q
K
R
L
A
V
Y
-
Q
A
G
A
R
E
G
A
E
R
G
L
S
A
I
R
E
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
38.29
18%
82
- C4 -
3R2P
-
APOA1_HUMAN
A:
[114-164]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
R
Q
-
K
-
V
E
P
L
-------
R
A
E
L
Q
E
G
A
R
Q
K
L
H
------
E
L
Q
E
K
L
S
P
L
-
G
E
E
M
R
D
R
A
R
A
H
V
D
A
L
R
T
H
L
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
37.64
20%
89
- C4 -
3P8C
1
BRK1_HUMAN
E:
[30-70]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
I
A
------
D
F
L
N
S
F
D
M
S
-
C
R
S
R
L
A
T
L
N
E
K
L
T
A
L
E
R
R
I
E
Y
I
E
A
R
V
T
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
32.87
18%
91
- C4 -
2A01
-
APOA1_HUMAN
A:
[114-164]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
R
Q
-
K
-
V
E
P
L
-------
R
A
E
L
Q
E
G
A
R
Q
K
L
H
------
E
L
Q
E
K
L
S
P
L
-
G
E
E
M
R
D
R
A
R
A
H
V
D
A
L
R
T
H
L
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
31.85
8%
76
- C4 -
3R2P
-
APOA1_HUMAN
A:
[92-139]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
K
A
-
K
-
V
Q
P
Y
-------
L
D
D
F
Q
K
K
W
Q
E
E
M
E
------
L
Y
R
Q
K
V
E
P
L
-
R
A
E
L
Q
E
G
A
R
Q
K
L
H
E
L
Q
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
31.41
21%
113
- C4 -
2L7B
-
APOE_HUMAN
A:
[109-155]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
V
C
G
-
R
-
L
V
Q
Y
-------
R
G
E
V
Q
A
M
L
G
Q
S
T
E
------
E
L
R
V
R
L
A
S
H
-
L
R
K
L
R
K
R
L
L
R
D
A
D
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
30.63
16%
156
- C4 -
2YY0
-
MYCBP_HUMAN
A:
[57-84]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P
E
N
P
E
I
E
L
L
R
L
E
L
A
E
M
K
E
K
Y
E
A
I
V
E
E
N
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------