@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA5072: (2016-03-04 )
MYDWWVLQLAKLSVSRKLMVGFGVLLALLLLVVISSNRTLTHQTALSEQLAEVASLMEQTQQAEQGRLAFEAGSDPRQAEQVRQTLAGMLQRLQALRDSELDPAALAHQVEAIEAYRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQAGDPQALQRSRAVADLHQQLLMVRYQVRGYVFERSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMGSLQGYRGGIEQFRAGVIRTRQAQQAMQSSTQDMARAGRTLTEAGRQLRESTASRDRASLWLIAALALAFGCVAGWAINRQIVRPLDEALAQAEAIAAGDLGKRPQNPLTLQRRDELGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTAASSGELARLGTQLQAQVGRFRL
Atome Classification :
(20 SA)
----------.........10........20...-------.....30........40........50........60..--......70.-.....-..80..-......90.......---.--------100.......110--.........120....----------------------------...130.......140......------------.150.......160...-.-.-..170.......180.......190.......200.....--------..210.......220.........230.......240.......250.--........260.......270.......280.......-290.......300.......310.......320..----------.....330...-....340.......350-------........360........370...---....380.......390---........400.......410.......---420....-----...-----------------------430..-.....440.......450.......--460..------------------...-------..470.......480.-......490.......500----------........510.......520....----...530.......540.......550.......560.---......570----.....--..580.......590.......600.......610.......620--------------.......630.......640.....---------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------MY
D
W
W
V
L
Q
L
A
K
L
S
V
S
R
K
L
M
V
G
F
G
V
-------
L
L
A
L
L
L
L
V
V
ISSNRTL
T
H
Q
T
A
L
S
E
Q
L
A
E
V
A
S
L
M
E
Q
T
Q
Q
A
--EQG
R
L
A
F
EA-GSD
P
R
-
Q
A
E
Q
V
R
-
Q
T
L
A
G
M
L
Q
R
L
Q
A
L
RD---S--------EL
D
P
A
A
L
A
H
Q
V
----
E
A
I
E
A
Y
R
K
A
F
D
D
L
A
A
A
----------------------------
D
Q
Q
R
S
AAR
G
V
L
VG
T
A
Q
Q
A
L
D
S
F
------------
A
R
L
E
E
L
M
D
A
S
L
A
Q
QAG
D
-
P
-
Q
-
A
L
Q
R
S
R
A
V
A
D
L
H
Q
Q
L
L
M
V
R
Y
Q
V
R
G
Y
V
F
ERSD
K
A
E
Q
A
A
F
A
A
--------
F
D
A
L
R
Q
A
A
T
T
L
RG--QLPG
E
A
D
A
A
L
E
Q
A
M
G
S
L
Q
G
Y
R
G
G
I
E
Q
F
R
A
G
--
V
--
I
R
T
R
Q
A
Q
Q
A
M
Q
S
S
T
Q
D
M
A
R
AG
R
T
L
T
E
A
G
R
Q
L
R
E
S
TASR-
D
R
A
S
L
W
L
I
A
A
L
A
L
A
F
G
C
VAGWAI
N
R
Q
I
V
R
P
L
D
E
A
L
----------
A
Q
A
E
A
IAAGDL-GKRPQNP
L
T
L
Q
R
R
D
E
L
--------
G
Q
L
Q
R
V
M
Q
R
M
-
G
D
S
L
R
E
L
V
G
R
I
S
D
G
---
V
S
Q
L
A
S
S
A
E
E
L
S
A
V
T
E
----
Q
T
RAGVNSQKV
E
T
D
Q
V
A
T
A
M
H
E
M
A
A
T
V
Q
---
D
V
A
R
N
A
E
-----
L
A
S
-----------------------
Q
A
A
R
Q
-
A
D
E
E
ARQG
D
A
V
V
D
Q
A
V
T
R
I
E
R
L
A
S
E--MDV
S
S
------------------
E
A
M
-------
A
R
L
KN
E
S
E
Q
I
G
S
V
L
D
V
-
I
K
S
V
A
E
QT
N
L
L
A
L
N
A
A
I
E
-----------
A
ARAGDAGR
G
F
A
V
V
A
D
E
V
R
G
L
A
Q
R
T
----
Q
Q
S
T
A
E
I
E
G
L
I
Q
R
L
Q
QGA
G
E
A
A
E
R
L
E
NSRSL
T
A
S
T
V
E
---
L
A
R
RA
G
A
A
L
----
D
S
I
T
R
--
T
V
S
D
I
QNM
N
L
Q
I
A
TA
A
E
Q
Q
S
T
V
A
E
E
I
N
R
S
V
L
S
V
R
D
V
A
E
Q
S
AAASE--------------QTAASS
G
E
L
A
R
L
G
T
Q
L
Q
A
Q
VGRFRL---------------------------------------------------------------
49
Fugue
77.85
23%
-37
- C5 -
2YFA
4
MCPS_PSEPK
A:
[18-253]
---------------------------------------------------------------
G
S
H
M
G
D
I
G
Q
L
N
K
D
L
T
D
L
--
R
I
A
R
L
Q
Y
M
I
A
N
G
D
D
T
-
A
A
A
N
T
L
-
A
K
L
D
A
F
S
K
Q
Q
A
Y
L
A
T
T
FK
S
--------
P
E
N
V
K
L
L
G
E
L
G
----
D
T
I
S
A
Y
K
L
S
L
N
K
M
R
Q
G
----------------------------
Y
D
A
T
R
A
A
R
V
S
M
D
S
S
A
I
R
A
D
Q
A
M
------------
D
A
L
S
Q
E
V
M
A
---
R
P
E
A
D
-
S
-
V
-
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
A
A
L
R
Q
--------
L
D
A
A
L
A
D
T
D
N
L
K
R
--
Q
L
-
P
S
E
D
A
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
V
R
Q
F
R
D
A
--
V
--
A
N
I
T
T
S
R
A
E
M
T
V
Q
G
A
D
I
V
K
R
S
D
A
L
Y
Q
I
Q
L
E
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.90
35%
-5
- C5 -
1QU7
-
MCP1_ECOLI
A:
[303-489]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
T
A
A
S
M
E
Q
L
T
A
T
V
K
---
Q
N
A
E
N
A
R
-----
Q
A
S
-----------------------
H
L
A
L
S
-
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
----------------------------------
Q
T
M
-------
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
-
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
-----------
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
----
A
Q
A
A
R
E
I
K
S
L
I
E
-------
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
----------
A
G
E
T
M
----
A
E
I
V
S
--
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
R
V
T
Q
Q
N
A
A
---------------------------------------------------------------------------------------------------------
47
Fugue
73.36
26%
-15
- C5 -
2CH7
2
MCP2_THEMA
A:
[1-309]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
M
K
D
V
Q
T
E
-
T
F
S
V
A
E
S
I
E
E
I
S
K
A
---
N
E
E
I
T
N
Q
L
L
G
I
S
K
E
M
D
----
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
E
T
T
A
G
S
E
E
I
S
S
A
T
K
---
N
I
A
D
S
A
Q
-----
Q
A
A
-----------------------
S
F
A
D
Q
-
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
--
A
K
D
V
E
------------------
R
V
V
-------
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
-
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
-----------
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
----
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
---
L
A
D
E
A
D
E
K
L
----
N
S
I
V
G
--
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
--------------
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
YK--------------------------------------------------
21
PsiBlast_CBE
72.19
33%
5
- C5 -
3ZX6
2
B:
[4-254]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
R
P
I
I
E
L
S
----------
N
T
V
D
K
I
A
E
G
N
L
E
A
E
V
P
H
Q
----
N
R
A
D
E
I
--------
G
I
L
A
K
S
I
E
R
L
-
R
R
S
L
M
R
T
V
G
D
V
R
N
G
---
A
N
A
I
Y
S
G
A
S
E
I
A
T
G
N
N
----
D
L
S
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
S
M
E
Q
L
T
A
T
V
K
---
Q
N
A
E
N
A
R
-----
Q
A
S
-----------------------
H
L
A
L
S
-
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
----------------------------------
Q
T
M
-------
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
-
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
-----------
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
----
A
Q
A
A
R
E
I
K
S
L
I
E
-------
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
----------
A
G
E
T
M
----
A
E
I
V
S
--
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
-------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
70.80
33%
1
- C5 -
3ZX6
1
MCP1_ECOLI
A:
[4-254]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
R
P
I
I
E
L
S
----------
N
T
V
D
K
I
A
E
G
N
L
E
A
E
V
P
H
Q
----
N
R
A
D
E
I
--------
G
I
L
A
K
S
I
E
R
L
-
R
R
S
L
M
R
T
V
G
D
V
R
N
G
---
A
N
A
I
Y
S
G
A
S
E
I
A
T
G
N
N
----
D
L
S
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
S
M
E
Q
L
T
A
T
V
K
---
Q
N
A
E
N
A
R
-----
Q
A
S
-----------------------
H
L
A
L
S
-
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
----------------------------------
Q
T
M
-------
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
-
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
-----------
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
----
A
Q
A
A
R
E
I
K
S
L
I
E
-------
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
----------
A
G
E
T
M
----
A
E
I
V
S
--
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
-------------------------------------------------------------------------------------------------------------------------------
48
Fugue
69.78
33%
-1
- C5 -
1QU7
-
MCP1_ECOLI
A:
[294-520]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
E
Q
Q
A
A
S
L
E
---
Q
T
A
A
S
M
E
-----
Q
L
T
-----------------------
A
T
V
K
Q
-
N
A
E
N
A
R
Q
A
S
H
L
A
L
S
A
S
E
T
A
Q
R
G
G
K
V
--
V
D
N
V
V
------------------
Q
T
M
-------
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
-
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
-----------
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
----
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
A
-----------------
G
E
T
M
----
A
E
I
V
S
--
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
R
V
T
Q
Q
N
A
A
L
V
E
--------------
Q
S
A
A
A
A
A
A
L
E
E
Q
A
S
R
L
T
E
A
V
A
V
F
R
I
QQQ------------------------------------------------------------
3
PsiBlast_PDB
69.37
36%
-14
- C5 -
2CH7
1
MCP2_THEMA
A:
[32-252]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
-
I
S
K
E
---
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
----
E
T
T
A
G
-------
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
Q
---
Q
A
A
S
F
A
D
-----
Q
S
T
-----------------------
Q
L
A
K
E
-
A
------
G
D
A
L
--
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
-------------------
V
V
-------
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
-
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
-----------
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
----
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
---
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
----
N
S
I
V
G
--
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
-------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
68.34
36%
-14
- C5 -
2CH7
1
MCP2_THEMA
B:
[32-252]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
-
I
S
K
E
---
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
----
E
T
T
A
G
-------
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
Q
---
Q
A
A
S
F
A
D
-----
Q
S
T
-----------------------
Q
L
A
K
E
-
A
------
G
D
A
L
--
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
-------------------
V
V
-------
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
-
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
-----------
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
----
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
---
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
----
N
S
I
V
G
--
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
N
A
A
V
D
E
I
-------------------------------------------------------------------------------------------------------------------------
25
HHSearch
67.69
38%
-3
- C5 -
1QU7
-
MCP1_ECOLI
A:
[299-517]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
S
L
E
Q
T
A
A
S
M
E
Q
L
T
A
T
V
K
---
Q
N
A
E
N
A
R
-----
Q
A
S
-----------------------
H
L
A
L
S
-
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
----------------
V
V
------------------
Q
T
M
-------
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
-
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
-----------
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
----
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
--------------
T
---
L
V
E
S
A
G
E
T
M
----
A
E
I
V
S
--
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
R
V
T
Q
Q
N
A
A
L
V
E
--------------
Q
S
A
A
A
A
A
A
L
E
E
Q
A
S
R
L
T
E
A
V
A
V
F
R
I
---------------------------------------------------------------
27
HHSearch
67.68
29%
-9
- C5 -
2CH7
2
MCP2_THEMA
A:
[61-309]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
S
S
A
T
K
---
N
I
A
D
S
A
Q
-----
Q
A
A
-----------------------
S
F
A
D
Q
-
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
--
A
K
D
V
E
------------------
R
V
V
-------
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
-
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
-----------
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
----
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
---
L
A
D
E
A
D
E
K
L
----
N
S
I
V
G
--
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
K
----------------------------------------------------------------
30
HHSearch
66.89
24%
-35
- C5 -
2YFA
4
MCPS_PSEPK
A:
[19-214]
----------------------------------------------------------------
S
H
M
G
D
I
G
Q
L
N
K
D
L
T
D
L
--
R
I
A
R
L
Q
Y
M
I
-
A
N
G
D
D
T
A
A
A
N
T
L
-
A
K
L
D
A
F
S
K
Q
Q
A
Y
L
A
T
---
T
--------
F
K
S
P
E
N
-
V
K
L
L
G
E
L
G
D
T
I
S
A
Y
K
L
S
L
N
K
M
R
Q
G
----------------------------
Y
D
A
T
R
A
A
R
V
S
M
D
S
S
A
I
R
A
D
Q
A
M
------------
D
A
L
S
Q
E
-----
V
M
-
A
R
P
E
A
D
S
V
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
A
A
L
R
Q
--------
L
D
A
A
L
A
D
T
D
N
L
K
R
--
Q
L
P
S
E
D
A
-
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.63
37%
-33
- C5 -
2YFA
2
MCPS_PSEPK
A:
[119-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
Q
A
M
D
A
L
------------
S
--
Q
E
V
M
----
A
R
P
E
A
D
-
S
-
V
-
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
A
A
L
R
Q
--------
L
D
A
A
L
A
D
T
D
N
L
K
R
--
Q
L
P
S
E
-
D
A
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
V
R
Q
F
R
D
A
--
V
A
N
I
T
T
S
R
A
E
M
T
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
65.35
37%
-32
- C5 -
2YFB
2
MCPS_PSEPK
A:
[119-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
Q
A
M
D
A
L
------------
S
--
Q
E
V
M
----
A
R
P
E
A
D
-
S
-
V
-
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
A
A
L
R
Q
--------
L
D
A
A
L
A
D
T
D
N
L
K
R
--
Q
L
P
S
E
-
D
A
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
V
R
Q
F
R
D
A
--
V
A
N
I
T
T
S
R
A
E
M
T
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
64.73
37%
-28
- C5 -
2YFA
3
MCPS_PSEPK
B:
[119-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
Q
A
M
D
A
L
------------
S
--
Q
E
V
M
----
A
R
P
E
A
D
-
S
-
V
-
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
A
A
L
R
Q
--------
L
D
A
A
L
A
D
T
D
N
L
K
R
--
Q
L
P
S
E
-
D
A
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
V
R
Q
F
R
D
A
--
V
A
N
I
T
T
S
R
A
E
M
T
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
Fugue
63.87
13%
-38
- C1 -
4ZUZ
-
?
A:
[7-863]
D
V
I
K
F
K
EPER
C
D
Y
L
Y
V
D
E
N
N
K
V
H
I
L
L
P
I
V
G
G
D
E
I
G
L
D
N
TC
Q
T
A
V
E
L
I
T
F
F
Y
G
S
A
H
S
G
V
T
K
Y
S
A
E
H
Q
L
S
E
Y
K
R
Q
L
E
E
D
I
K
A
I
N
S
Q
K
K
I
S
P
H
A
-
Y
D
D
L
L
-
K
E
K
I
E
R
L
Q
Q
I
E
K
Y
I
E
L
I
Q
V
L
K
K
---
Q
YDEQN
D
I
R
Q
L
R
T
G
G
I
P
Q
L
P
----
S
G
V
K
E
I
I
K
S
S
E
N
A
F
A
V
R
L
S
P
YDNDKFTRFDDPL
F
N
V
K
R
N
ISKYD
T
P
S
R
Q
A
P
I
P
I
Y
E
G
L
G
Y
R
L
R
S
T
L
FPEDK
T
P
T
P
I
N
K
K
S
L
R
D
K
V
K
S
T
V
L
S
H
Y
K
D
-
E
-
D
-
R
I
D
G
E
K
K
D
E
K
L
N
E
L
I
T
N
L
Q
N
E
L
V
K
E
L
V
K
S
D
P
Q
Y
S
K
L
S
L
S
K
DPRG
K
E
I
N
Y
D
Y
L
V
N
S
L
M
L
V
D
N
DS
E
I
G
D
W
I
D
T
I
L
D
A
T
V
D
S
T
V
W
A
V
Q
A
S
S
P
F
Y
Q
G
AK
E
--
I
S
S
D
R
D
A
D
K
I
S
I
R
V
Q
Y
L
L
A
E
A
N
I
Y
C
K
T
N
K
L
S
D
A
N
F
G
E
F
F
D
K
E
P
H
A
T
E
I
A
K
R
V
K
E
G
F
T
Q
G
A
D
I
E
P
I
I
Y
D
Y
I
N
S
N
H
AELGLKSPLT
G
K
Q
Q
Q
E
I
T
D
K
F
-
T
K
H
Y
N
T
I
K
E
S
P
H
F
D
E
F
F
V
A
D
PDKK
G
N
I
F
S
H
Q
G
R
I
-
S
C
H
F
L
D
F
F
T
R
Q
T
K
G
KHP
L
G
D
L
A
S
H
Q
E
A
L
Q
E
G
T
S
NRLH
H
K
N
E
V
V
A
Q
G
Y
E
K
L
D
Q
F
K
K
E
V
V
K
L
L
A
E
N
K
---
P
K
E
L
L
D
Y
-----
L
V
A
TSPTGVPNYSMLS
K
E
T
Q
N
Y
I
A
Y
N
R
N
W
P
A
-
I
Q
K
E
L
E
K
A
T
S
I
P
E
S
Q
K
Q
D
L
S
R
L
L
S
R
--
D
N
L
Q
H
------------------
D
N
L
-------
S
A
I
T
W
S
K
Y
S
S
K
P
L
L
D
V
E
L
N
K
I
A
E
G
L
E
L
T
A
K
I
Y
N
E
K
RGREWWFAGSR
N
E
A
R
K
T
Q
C
E
E
L
Q
R
V
S
K
E
I
N
T
L
L
Q
S
E
SLT
K
S
Q
V
L
E
K
V
L
N
S
I
E
T
L
D
K
I
D
R
D
I
S
A
E
S
N
W
F
Q
S
T
L
Q
K
E
V
R
---
L
F
R
D
Q
L
K
D
I
----
C
Q
L
D
K
Y
Y
F
K
S
T
K
L
D
E
I
I
S
L
E
M
E
E
Q
F
Q
K
I
Q
D
P
A
V
Q
Q
I
V
R
D
L
P
S
H
C
H
N
D
E
A
I
E
F
--------------
F
K
T
L
N
P
E
E
A
A
K
V
A
S
Y
L
S
L
E
Y
R
E
I
N
K
STDK
K
T
L
L
E
Q
D
I
P
R
L
F
K
E
V
N
T
Q
L
L
S
K
L
K
E
E
KAID
E
Q
V
H
E
K
L
S
Q
L
ADKIAPEHFT
R
N
N
I
I
K
W
S
T
23
PsiBlast_CBE
63.82
37%
-30
- C5 -
2YFB
2
MCPS_PSEPK
B:
[119-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
Q
A
M
D
A
L
------------
S
--
Q
E
V
M
----
A
R
P
E
A
D
-
S
-
V
-
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
A
A
L
R
Q
--------
L
D
A
A
L
A
D
T
D
N
L
K
R
--
Q
L
P
S
E
-
D
A
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
V
R
Q
F
R
D
A
--
V
A
N
I
T
T
S
R
A
E
M
T
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
62.87
24%
0
- C5 -
3VKG
-
?
A:
[1910-2244]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
R
D
Q
L
--------
E
E
E
Q
L
H
L
N
I
G
-
L
K
K
L
R
D
T
E
A
Q
V
K
D
L
---
Q
V
S
L
A
Q
K
N
R
E
L
D
V
K
N
E
----
Q
A
N
Q
K
L
K
-
Q
M
V
Q
D
Q
Q
A
A
E
I
K
Q
K
D
A
R
E
L
Q
V
Q
L
D
V
-
R
N
K
E
-----
I
A
V
-----------------------
Q
K
V
K
A
Y
A
D
L
-------
P
L
R
E
E
V
E
Q
L
E
N
A
A
N
E
--
L
K
L
K
Q
D
E
I
V
A
T
I
T
A
L
E
K
S
I
A
T
Y
K
E
E
Y
-------
A
T
L
I
R
E
T
E
Q
I
K
T
E
S
S
K
-
V
K
N
K
V
D
R
S
I
A
L
L
D
N
L
N
S
E
-----------
R
G
R
W
E
Q
Q
S
E
N
F
N
T
Q
M
S
T
V
V
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
59.34
25%
8
- C5 -
3G67
-
?
A:
[81-251]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
N
I
M
E
E
L
K
K
S
G
T
N
V
D
Q
I
V
E
R
--
V
K
E
A
S
------------------
S
Q
I
-------
G
E
T
L
E
N
I
R
S
I
E
K
L
I
Q
N
-
I
M
R
I
A
R
E
T
N
I
L
A
L
N
A
T
I
E
-----------
A
A
R
A
G
E
A
G
K
G
F
M
I
V
A
N
E
V
Q
N
L
S
N
E
T
----
N
E
V
T
K
Q
I
V
E
K
A
R
E
I
L
E
S
S
Q
R
S
L
E
N
L
E
F
M
A
N
----------
L
F
E
T
V
G
K
T
L
----
Q
N
M
V
R
--
F
M
E
N
N
V
K
L
L
Q
E
V
R
N
S
L
D
T
S
K
E
S
L
S
E
K
S
A
E
I
D
S
A
T
K
V
L
E
E
------------------------------------------------------------------------------------------------------------
52
Fugue
56.72
11%
-17
- C5 -
3I9Y
-
?
A:
[50-317]
------------------------------------------------------
S
A
M
I
E
A
R
Q
V
S
E
L
S
T
R
I
I
S
S
V
Q
M
L
S
N
A
--
Q
------
N
E
-
Q
E
R
K
E
-
A
G
R
V
L
F
-
E
Q
L
E
S
L
L
T
H
I
K
E
L
G
G
---
E
--------
S
F
D
S
K
L
L
D
A
L
E
----
S
N
V
Q
N
V
I
N
N
L
A
E
L
G
V
T
----------------------------
V
E
R
K
L
W
L
A
K
E
I
D
T
R
V
E
E
M
R
L
L
S
------------
E
E
L
E
Q
L
T
R
-
T
L
D
L
T
E
R
L
-
H
-
E
-
L
H
L
L
A
F
K
M
L
N
Q
I
E
E
A
R
T
L
---------
T
N
V
D
R
I
Q
Q
I
Q
T
A
F
--------
E
N
N
L
K
I
M
K
R
R
V
L
A
--
V
E
D
P
T
R
S
K
Q
M
S
Q
L
L
T
E
L
G
K
R
Q
V
V
F
T
I
L
L
Q
Q
--
Y
--
E
N
N
E
Q
S
Q
Q
L
M
Q
K
T
L
E
L
F
S
E
L
N
S
T
V
N
K
L
V
D
D
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
55.49
14%
5
- C3 -
4O5J
3
?
A:
[27-400]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
N
L
N
E
K
Y
-
E
Q
L
S
Q
Y
L
N
Q
V
A
S
L
K
Q
S
I
Q
N
A
-----
N
N
I
E
L
V
N
S
S
L
----------
N
Y
L
K
S
F
T
N
N
N
Y
-
N
S
T
T
Q
S
P
I
F
N
A
V
Q
A
V
I
--------
T
S
V
L
G
F
W
S
L
Y
A
G
N
Y
F
T
F
F
V
G
K
K
V
D
S
----
G
Q
P
A
S
V
Q
G
N
P
P
F
K
T
I
----
I
E
N
C
S
G
I
E
N
C
A
M
D
Q
T
T
Y
D
K
M
K
K
L
A
E
D
L
Q
---
A
A
Q
T
N
S
A
TKGNN
L
C
A
-----------------------
L
S
G
C
A
-
A
T
S
N
P
P
N
S
T
--
V
S
N
A
L
N
L
A
Q
Q
L
M
D
L
--
I
A
N
T
K
------------------
T
A
M
M
WKN
I
V
I
S
G
V
S
N
T
S
G
A
I
T
S
T
N
Y
P
-
T
Q
Y
A
V
F
N
N
I
K
A
M
I
P
I
L
Q
Q
-----------
A
V
T
L
S
Q
S
N
H
T
L
S
A
S
L
Q
A
Q
A
T
G
S
Q
T
N
----
P
K
F
A
K
D
I
Y
T
F
A
Q
N
Q
K
Q
V
I
S
Y
A
Q
D
I
F
N
L
F
N
S
I
P
A
E
Q
Y
K
---
Y
L
E
K
A
Y
L
K
I
PNAG
S
T
P
T
N
--
P
Y
R
Q
V
V
N
L
N
Q
E
V
Q
T
I
K
N
N
V
S
Y
Y
G
N
R
V
D
A
A
L
S
V
A
R
D
V
Y
N
L
K
S
N
Q
A
E
--------------
I
V
T
A
Y
N
-
D
A
K
T
L
S
E
E
I
S
K
L
P
H
-------------------------------------------------------------------