@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA5322: (2016-03-06 )
MSTAKAPTLPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIVVAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF
Atome Classification :
(20 SA)
.........10........20........30........40--.....--...50........60........70........80........90.....--------...100--------.......110.......120........130.......140...----.----...150.......160...--....----170..--.....180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......--370.......380.......390......-.400........410.......420.......430.......440.......450.......460.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSTAKAPTL
P
A
S
I
F
R
A
YDIRGVVGDTLT
A
E
T
A
Y
W
I
G
R
AIGS--ESLAR--GEP
C
V
A
VGRDGRLS
G
P
E
L
V
K
Q
L
I
Q
G
L
V
DCGCQVSDVGMVP
T
P
V
L
Y
Y
A
A
N
V
--------LEGKS
G
--------
V
M
L
TGSHNPPDYN
G
F
K
I
V
V-AGET
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----G----VGS
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
AM----AK
P
M
K
--
V
V
V
DCGNG
V
A
G
V
I
A
P
Q
L
I
E
A
LGC
S
V
I
P
L
Y
C
E
VDGNFPNHHPDPGK
P
E
N
L
K
D
L
I
A
K
V
KAENA
D
L
G
L
A
FDGDG
D
R
V
G
V
V
TNT
G
T
I
IY
P
D
R
L
L
M
L
F
A
K
D
V
VSRNPGA
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
SGYGGRP
V
M
WKT
G
H
S
L
I
K
K
K
M
K
ETG
A
L
L
AGEMSG
H
V
F
F
K
ERWFGFD
D
G
I
Y
S
A
A
R
L
L
E
I
L
SQDQRD
S
E
H
V
F
S
AFPS--DISTP
E
I
N
I
T
VTEDS
K
F
A
I
I
E
A
L
Q
RDAQW-GE-G
N
I
T
T
LD
G
V
R
VDYPKGW
G
L
V
R
ASNTT
P
V
L
V
L
R
FEAD
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
DSSLPVPF
46
Fugue
99.97
99%
-114
- C1 -
1K2Y
2
ALGC_PSEAE
X:
[5-463]
----
K
A
P
T
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
A
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
1
PsiBlast_PDB
99.97
99%
-114
- C1 -
1K2Y
2
ALGC_PSEAE
X:
[5-463]
----
K
A
P
T
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
A
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
11
PsiBlast_PDB
98.97
99%
-114
- C1 -
3C04
1
ALGC_PSEAE
A:
[6-463]
-----
A
P
T
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
G
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
10
PsiBlast_PDB
98.40
99%
-111
- C1 -
3BKQ
2
ALGC_PSEAE
X:
[6-463]
-----
A
P
T
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
G
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
13
PsiBlast_PDB
98.28
100%
-113
- C1 -
4MRQ
13
ALGC_PSEAE
A:
[1-455]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
12
PsiBlast_PDB
98.25
99%
-111
- C1 -
4IL8
3
ALGC_PSEAE
A:
[5-463]
----
K
A
P
T
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
A
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
8
PsiBlast_PDB
98.16
99%
-112
- C1 -
2FKF
2
ALGC_PSEAE
A:
[8-462]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
5
PsiBlast_PDB
98.10
99%
-110
- C1 -
1PCM
2
ALGC_PSEAE
X:
[9-463]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
24
HHSearch
97.94
100%
-109
- C1 -
1P5D
2
ALGC_PSEAE
X:
[9-463]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
2
PsiBlast_PDB
97.74
99%
-109
- C1 -
1P5D
2
ALGC_PSEAE
X:
[9-463]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
14
PsiBlast_PDB
97.72
98%
-113
- C1 -
1K35
1
ALGC_PSEAE
A:
[9-463]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
6
PsiBlast_PDB
97.47
99%
-110
- C1 -
2H4L
2
ALGC_PSEAE
X:
[9-463]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
3
PsiBlast_PDB
96.97
99%
-108
- C1 -
1P5G
2
ALGC_PSEAE
X:
[9-463]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
7
PsiBlast_PDB
96.87
99%
-108
- C1 -
2H5A
2
ALGC_PSEAE
X:
[9-463]
--------
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
9
PsiBlast_PDB
96.71
99%
-108
- C1 -
2FKM
2
ALGC_PSEAE
X:
[9-462]
---------
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
D
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
4
PsiBlast_PDB
96.67
99%
-108
- C1 -
1PCJ
2
ALGC_PSEAE
X:
[6-463]
-----
A
P
T
L
P
A
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
--
E
S
L
A
R
--
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
--------
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
-
A
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
----
G
----
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
--
D
I
A
M
----
A
K
P
M
K
--
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
--
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
-
G
E
-
G
N
I
T
T
L
D
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
V
D
S
S
L
P
V
P
F
25
HHSearch
84.97
56%
-104
- C1 -
3UW2
10
?
A:
[22-485]
-------
M
I
S
Q
S
I
F
K
A
Y
D
I
R
G
V
I
G
K
T
L
D
A
D
V
A
R
S
I
G
R
A
F
G
S
--
E
V
R
A
Q
--
G
G
D
A
V
V
V
A
R
D
G
R
L
S
G
P
E
L
V
G
A
L
A
D
G
L
R
A
A
G
V
D
V
V
D
V
G
M
V
P
T
P
V
G
Y
F
A
A
S
V
PLALSG
G
E
R
R
V
D
S
C
--------
I
V
V
T
G
S
H
N
P
P
D
Y
N
G
F
K
M
V
L
-
R
G
A
A
I
Y
G
D
Q
I
Q
G
L
Y
K
R
I
V
D
A
R
F
E
T
----
G
----
S
G
S
Y
E
Q
Y
D
V
A
D
Q
Y
V
E
R
I
V
G
--
D
I
K
L
----
T
R
P
L
K
--
L
V
V
D
A
G
N
G
V
A
G
P
L
A
T
R
L
F
K
A
L
G
C
E
L
V
E
L
F
T
D
I
D
G
N
F
P
N
H
H
P
D
P
A
H
P
E
N
L
Q
D
V
I
A
K
L
K
A
T
D
A
E
I
G
F
A
F
D
G
D
G
D
R
L
G
V
V
T
K
D
G
Q
I
I
Y
P
D
R
Q
L
M
L
F
A
E
E
V
L
S
R
N
P
G
A
Q
I
I
Y
D
V
K
C
T
R
N
L
A
R
W
V
R
E
K
G
G
E
P
L
M
W
K
T
G
H
S
L
V
K
A
K
L
R
E
T
G
A
P
L
A
G
E
M
S
G
H
V
F
F
K
D
R
W
Y
G
F
D
D
G
L
Y
T
G
A
R
L
L
E
I
L
A
R
V
-
A
D
P
S
A
L
L
N
G
L
P
N
--
A
V
S
T
P
E
L
Q
L
------
N
V
K
L
I
D
K
L
R
A
D
A
K
F
-
D
G
A
D
E
V
V
T
I
D
G
L
R
V
E
Y
P
D
G
F
G
L
A
R
S
S
N
T
T
P
V
V
V
L
R
F
E
A
T
S
D
A
A
L
A
R
I
Q
D
D
F
R
R
A
L
K
A
A
K
P
G
A
N
L
P
F
15
PsiBlast_PDB
83.51
55%
-104
- C1 -
3UW2
10
?
A:
[26-485]
-----------
S
I
F
K
A
Y
D
I
R
G
V
I
G
K
T
L
D
A
D
V
A
R
S
I
G
R
A
F
G
S
--
E
V
R
A
Q
--
G
G
D
A
V
V
V
A
R
D
G
R
L
S
G
P
E
L
V
G
A
L
A
D
G
L
R
A
A
G
V
D
V
V
D
V
G
M
V
P
T
P
V
G
Y
F
A
A
S
V
--------
P
L
A
L
S
G
G
E
R
R
V
D
S
C
I
V
V
T
G
S
H
N
P
P
D
Y
N
G
F
K
M
V
L
-
R
G
A
A
I
Y
G
D
Q
I
Q
G
L
Y
K
R
I
V
D
A
R
F
E
T
----
G
----
S
G
S
Y
E
Q
Y
D
V
A
D
Q
Y
V
E
R
I
V
G
--
D
I
K
L
----
T
R
P
L
K
--
L
V
V
D
A
G
N
G
V
A
G
P
L
A
T
R
L
F
K
A
L
G
C
E
L
V
E
L
F
T
D
I
D
G
N
F
P
N
H
H
P
D
P
A
H
P
E
N
L
Q
D
V
I
A
K
L
K
A
T
D
A
E
I
G
F
A
F
D
G
D
G
D
R
L
G
V
V
T
K
D
G
Q
I
I
Y
P
D
R
Q
L
M
L
F
A
E
E
V
L
S
R
N
P
G
A
Q
I
I
Y
D
V
K
C
T
R
N
L
A
R
W
V
R
E
K
G
G
E
P
L
M
W
K
T
G
H
S
L
V
K
A
K
L
R
E
T
G
A
P
L
A
G
E
M
S
G
H
V
F
F
K
D
R
W
Y
G
F
D
D
G
L
Y
T
G
A
R
L
L
E
I
L
A
R
-
V
A
D
P
S
A
L
L
N
G
L
P
N
--
A
V
S
T
P
E
L
Q
L
------
N
V
K
L
I
D
K
L
R
A
D
A
K
F
D
G
A
-
D
E
V
V
T
I
D
G
L
R
V
E
Y
P
D
G
F
G
L
A
R
S
S
N
T
T
P
V
V
V
L
R
F
E
A
T
S
D
A
A
L
A
R
I
Q
D
D
F
R
R
A
L
K
A
A
K
P
G
A
N
L
P
F
27
HHSearch
70.69
31%
-87
* C1 *
1WQA
1
?
A:
[2-454]
----------
G
K
L
F
G
T
F
G
V
R
G
I
A
N
E
K
I
T
P
E
F
A
M
K
I
G
M
A
F
G
T
--
L
L
K
R
E
GR
K
K
P
L
V
V
V
G
R
D
T
R
V
S
G
E
M
L
K
E
A
L
I
S
G
L
L
S
V
G
C
D
V
I
D
V
G
I
A
P
T
P
A
V
Q
W
A
T
K
H
--------
F
N
A
D
G
G
--------
A
V
I
T
A
S
H
N
P
P
E
Y
N
G
I
K
L
L
E
P
N
G
M
G
L
K
K
E
R
E
A
I
V
E
E
L
F
F
K
E
D
F
D
R
AKWY
E
----
I
G
E
V
R
R
E
D
I
I
K
P
Y
I
E
A
I
K
S
--
K
V
D
V
E
A
I
K
K
R
K
P
F
--
V
V
V
D
T
S
N
G
A
G
S
L
T
L
P
Y
L
L
R
E
L
G
C
K
V
I
T
V
N
A
Q
P
D
G
Y
F
P
A
R
N
P
E
P
N
-
E
E
N
L
K
E
F
M
E
I
V
K
A
L
G
A
D
F
G
V
A
Q
D
G
D
A
D
R
A
V
F
I
D
E
N
G
R
F
I
Q
G
D
K
T
F
A
L
V
A
D
A
V
L
K
E
K
G
G
G
L
L
V
T
T
V
A
T
S
N
L
L
D
D
I
A
K
K
H
G
A
K
V
M
R
T
K
V
G
D
L
I
V
A
R
A
L
Y
E
N
N
G
T
I
G
G
E
E
N
G
G
V
I
F
P
E
H
V
-
L
G
R
D
G
A
M
T
V
A
K
V
V
E
I
F
A
K
S
G
K
K
F
S
E
L
I
D
E
L
P
K
--
Y
Y
Q
-
I
K
T
K
R
H
V
E
G
-
D
R
H
A
I
V
N
K
V
A
E
M
A
R
E
-
R
G
-
Y
T
V
D
T
T
D
G
A
K
I
I
F
E
D
G
W
V
L
V
R
A
S
G
T
E
P
I
I
R
I
F
S
E
A
K
S
K
E
K
A
Q
E
Y
L
N
L
G
I
E
L
L
E
K
A
L
-------
21
PsiBlast_CBE
68.60
32%
-85
- C1 -
1WQA
1
?
D:
[3-440]
-----------
K
L
F
G
T
F
G
V
R
G
I
A
N
E
K
I
T
P
E
F
A
M
K
I
G
M
A
F
G
T
LL
K
R
E
G
R
--
K
K
P
L
V
V
V
G
R
D
T
R
V
S
G
E
M
L
K
E
A
L
I
S
G
L
L
S
V
G
C
D
V
I
D
V
G
I
A
P
T
P
A
V
Q
W
A
T
K
H
--------
F
N
A
D
G
G
--------
A
V
I
T
A
S
H
N
P
P
E
Y
N
G
I
K
L
L
E
P
N
G
M
G
L
K
K
E
R
E
A
I
V
E
E
L
F
F
K
E
D
F
D
R
----
A
KWYE
I
G
E
V
R
R
E
D
I
I
K
P
Y
I
E
A
I
K
S
KV
D
V
E
A
----
I
K
K
R
K
PF
V
V
V
D
T
S
N
G
A
G
S
L
T
L
P
Y
L
L
R
E
L
G
C
K
V
I
T
V
N
A
Q
P
D
G
Y
F
P
A
R
N
P
E
P
N
E
-
E
N
L
K
E
F
M
E
I
V
K
A
L
G
A
D
F
G
V
A
Q
D
G
D
A
D
R
A
V
F
I
D
E
N
G
R
F
I
Q
G
D
K
T
F
A
L
V
A
D
A
V
L
K
E
K
G
G
G
L
L
V
T
T
V
A
T
S
N
L
L
D
D
I
A
K
K
H
G
A
K
V
M
R
T
K
V
G
D
L
I
V
A
R
A
L
Y
E
N
N
G
T
I
G
G
E
E
N
G
G
V
I
F
P
E
H
V
L
G
-
R
D
G
A
M
T
V
A
K
V
V
E
I
F
A
K
S
G
K
K
F
S
E
L
I
D
E
L
P
K
YY
Q
I
K
T
K
R
----
H
V
E
G
D
R
H
A
I
V
N
K
V
A
E
M
A
R
E
-
R
G
-
Y
T
V
D
T
T
D
G
A
K
I
I
F
E
D
G
W
V
L
V
R
A
S
G
T
E
P
I
I
R
I
F
S
E
A
K
S
K
E
K
A
Q
---------------------