@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA5334: (2016-03-06 )
MNRPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGVPRFLKGQGQGWLTAEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDLSKLGENTLYIDCDVIQADGGTRTASITGATVALIDALAVLKKRGALKGNPLKQMVAAVSVGIYQGVPVLDLDYLEDSAAETDLNVVMTDAGGFIEVQGTAEGAPFRPAELNAMLELAQQGMQELFELQRAALAE
Atome Classification :
(32 SA)
.........10........20........30........40.......-.50-........60........70........80........90........100.......110.......120.......130.......140.......150-.-......160.....--.--.-170.......180.......190.-.-...---..200.--......210.......220.......230.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNRPSGRAADQL
R
P
I
R
I
T
R
H
Y
TKHAEG
S
V
L
V
E
FGD
T
K
V
I
C
T
VSAESGV-
P
R
F
-
L
KGQGQ
G
W
L
T
AEYGMLPRSTGER
N
Q
R
E
A
SRGKQGG
R
T
L
E
I
Q
R
L
I
G
R
S
L
R
A
A
L
D
L
S
K
LGEN
T
L
Y
I
D
C
D
V
I
QADGG
T
R
T
A
SIT
G
A
T
V
A
L
I
D
A
L
A
V
L
K
KRGALK-G-
N
P
L
K
Q
M
V
A
A
V
S
V
G
I
--Y--Q-GV
P
V
L
D
L
D
Y
LEDSAAET
D
L
N
V
V
M
T-D-AG
G
---
F
I
E
V
Q
G--TAEGAPFR
P
A
E
L
N
A
M
L
E
L
A
Q
Q
G
M
Q
E
L
F
E
L
Q
R
A
ALAE
66
HHSearch
97.22
100%
-97
- C1 -
1R6L
7
RNPH_PSEAE
A:
[1-239]
M
N
R
P
S
G
R
A
A
D
Q
L
R
P
I
R
I
T
R
H
Y
T
K
H
A
E
G
S
V
L
V
E
F
G
D
T
K
V
I
C
T
V
S
A
E
S
G
V
-
P
R
F
-
L
K
---
Q
G
W
L
T
A
E
Y
G
M
L
P
R
S
T
G
E
R
N
Q
R
E
A
S
R
G
K
Q
G
G
R
T
L
E
I
Q
R
L
I
G
R
S
L
R
A
A
L
D
L
S
K
L
G
E
N
T
L
Y
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
T
V
A
L
I
D
A
L
A
V
L
K
K
R
G
A
L
K
-
G
-
N
P
L
K
Q
M
V
A
A
V
S
V
G
I
--
Y
--
Q
-
G
V
P
V
L
D
L
D
Y
L
E
D
S
A
A
E
T
D
L
N
V
V
M
T
-
D
-
A
G
G
---
F
I
E
V
Q
G
--
T
A
E
G
A
P
F
R
P
A
E
L
N
A
M
L
E
L
A
Q
Q
G
M
Q
E
L
F
E
L
Q
R
A
A
L
A
E
1
PsiBlast_PDB
96.12
100%
-98
- C1 -
1R6M
1
RNPH_PSEAE
A:
[1-239]
M
N
R
P
S
G
R
A
A
D
Q
L
R
P
I
R
I
T
R
H
Y
T
K
H
A
E
G
S
V
L
V
E
F
G
D
T
K
V
I
C
T
V
S
A
E
S
G
V
-
P
R
F
-
L
K
---
Q
G
W
L
T
A
E
Y
G
M
L
P
R
S
T
G
E
R
N
Q
R
E
A
S
R
G
K
Q
G
G
R
T
L
E
I
Q
R
L
I
G
R
S
L
R
A
A
L
D
L
S
K
L
G
E
N
T
L
Y
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
T
V
A
L
I
D
A
L
A
V
L
K
K
R
G
A
L
K
-
G
-
N
P
L
K
Q
M
V
A
A
V
S
V
G
I
--
Y
--
Q
-
G
V
P
V
L
D
L
D
Y
L
E
D
S
A
A
E
T
D
L
N
V
V
M
T
-
D
-
A
G
G
---
F
I
E
V
Q
G
--
T
A
E
G
A
P
F
R
P
A
E
L
N
A
M
L
E
L
A
Q
Q
G
M
Q
E
L
F
E
L
Q
R
A
A
L
A
E
2
PsiBlast_PDB
95.61
97%
-97
- C1 -
1R6L
7
RNPH_PSEAE
A:
[2-239]
-
N
R
P
S
G
R
A
A
D
Q
L
R
P
I
R
I
T
R
H
Y
T
K
H
A
E
G
S
V
L
V
E
F
G
D
T
K
V
I
C
T
V
S
A
E
S
G
V
-
P
R
F
-
L
K
---
Q
G
W
L
T
A
E
Y
G
M
L
P
R
S
T
G
E
R
N
Q
R
E
A
S
R
G
K
Q
G
G
R
T
L
E
I
Q
R
L
I
G
R
S
L
R
A
A
L
D
L
S
K
L
G
E
N
T
L
Y
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
T
V
A
L
I
D
A
L
A
V
L
K
K
R
G
A
L
K
-
G
-
N
P
L
K
Q
M
V
A
A
V
S
V
G
I
--
Y
--
Q
-
G
V
P
V
L
D
L
D
Y
L
E
D
S
A
A
E
T
D
L
N
V
V
M
T
-
D
-
A
G
G
---
F
I
E
V
Q
G
--
T
A
E
G
A
P
F
R
P
A
E
L
N
A
M
L
E
L
A
Q
Q
G
M
Q
E
L
F
E
L
Q
R
A
A
L
A
E
5
PsiBlast_PDB
86.52
56%
-94
- C1 -
3DD6
5
RNPH_BACAN
A:
[12-249]
--
R
V
D
G
R
E
K
T
E
L
R
H
I
H
I
H
T
N
Y
L
K
H
P
E
G
S
V
L
I
E
V
G
D
T
K
V
I
C
S
A
T
I
E
E
R
V
-
P
P
F
-
M
R
G
E
G
K
G
W
V
T
A
E
Y
A
M
I
P
R
A
T
E
Q
R
T
I
R
E
S
S
-
G
K
V
T
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
A
L
G
E
R
T
V
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
Y
V
A
M
V
L
A
F
E
K
L
L
Q
A
E
K
V
S
-
K
-
I
P
V
K
D
Y
L
A
A
T
S
V
G
I
--
V
EE
Q
-
G
V
-
V
L
D
L
N
Y
A
E
D
S
K
A
D
V
D
M
N
V
I
M
T
-
G
-
K
G
Q
---
F
V
E
V
Q
G
--
T
G
E
E
A
T
F
S
R
A
Q
L
N
E
L
L
D
A
A
E
Q
G
I
F
Q
L
I
D
I
Q
K
E
A
L
G
D
67
HHSearch
85.66
55%
-91
- C1 -
3DD6
5
RNPH_BACAN
A:
[11-249]
-
M
R
V
D
G
R
E
K
T
E
L
R
H
I
H
I
H
T
N
Y
L
K
H
P
E
G
S
V
L
I
E
V
G
D
T
K
V
I
C
S
A
T
I
E
E
R
V
-
P
P
F
-
M
R
G
E
G
K
G
W
V
T
A
E
Y
A
M
I
P
R
A
T
E
Q
R
T
I
R
E
S
S
-
G
K
V
T
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
A
L
G
E
R
T
V
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
Y
V
A
M
V
L
A
F
E
K
L
L
Q
A
E
K
V
S
-
K
-
I
P
V
K
D
Y
L
A
A
T
S
V
G
I
--
V
--
E
E
Q
G
V
V
L
D
L
N
Y
A
E
D
S
K
A
D
V
D
M
N
V
I
M
T
-
G
-
K
G
Q
---
F
V
E
V
Q
G
--
T
G
E
E
A
T
F
S
R
A
Q
L
N
E
L
L
D
A
A
E
Q
G
I
F
Q
L
I
D
I
Q
K
E
A
L
G
D
23
PsiBlast_CBE
85.10
56%
-96
- C1 -
1OYR
3
RNPH_BACSU
D:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
P
R
A
T
N
Q
R
T
I
R
E
S
S
K
G
K
I
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
25
PsiBlast_CBE
84.99
56%
-94
- C1 -
1OYR
2
RNPH_BACSU
B:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
P
R
A
T
N
Q
R
T
I
R
E
S
S
K
G
K
I
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
22
PsiBlast_CBE
84.89
56%
-95
- C1 -
1OYR
3
RNPH_BACSU
E:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
P
R
A
T
N
Q
R
T
I
R
E
S
S
K
G
K
I
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
4
PsiBlast_PDB
84.66
56%
-94
- C1 -
1OYR
3
RNPH_BACSU
A:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
P
R
A
T
N
Q
R
T
I
R
E
S
S
K
G
K
I
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
D
K
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
24
PsiBlast_CBE
84.49
56%
-94
- C1 -
1OYR
2
RNPH_BACSU
C:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
P
R
A
T
N
Q
R
T
I
R
E
S
S
K
G
K
I
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
35
PsiBlast_CBE
84.12
56%
-93
- C1 -
3B4T
2
RNPH_MYCTU
B:
[6-243]
-
K
R
E
D
G
R
L
D
H
E
L
R
P
V
I
I
T
R
G
F
T
E
N
P
A
G
S
V
L
I
E
F
G
H
T
K
V
L
C
T
A
S
V
T
E
G
V
-
P
--------
L
G
W
L
T
A
E
Y
A
M
L
P
S
A
T
H
S
R
S
D
R
E
S
V
R
G
R
L
S
G
R
T
Q
E
I
S
R
L
I
G
R
S
L
R
A
C
I
D
L
A
A
L
G
E
N
T
I
A
I
D
C
D
V
L
Q
A
D
G
G
T
R
T
A
A
I
T
G
A
Y
V
A
L
A
D
A
V
T
Y
L
S
A
A
G
K
L
S
-
D
P
R
P
L
S
C
A
I
A
A
V
S
V
G
V
--
V
--
D
-
G
R
I
R
V
D
L
P
Y
E
E
D
S
R
A
E
V
D
M
N
V
V
A
T
-
D
-
T
G
T
---
L
V
E
I
Q
G
--
T
G
E
G
A
T
F
A
R
S
T
L
D
K
L
L
D
M
A
L
G
A
C
D
T
L
F
A
A
Q
R
D
A
L
A
-
21
PsiBlast_CBE
83.91
56%
-94
- C1 -
1OYR
2
RNPH_BACSU
F:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
P
R
A
T
N
Q
R
T
I
R
E
S
S
K
G
K
I
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
26
PsiBlast_CBE
83.67
56%
-102
- C1 -
1OYP
2
RNPH_BACSU
F:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
-----------------
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
34
PsiBlast_CBE
83.32
56%
-96
- C1 -
3B4T
3
RNPH_MYCTU
C:
[6-243]
-
K
R
E
D
G
R
L
D
H
E
L
R
P
V
I
I
T
R
G
F
T
E
N
P
A
G
S
V
L
I
E
F
G
H
T
K
V
L
C
T
A
S
V
T
E
G
V
-
P
R
W
------
L
G
W
L
T
A
E
Y
A
M
L
P
S
A
T
H
S
R
S
D
R
E
S
V
R
G
R
L
S
G
R
T
Q
E
I
S
R
L
I
G
R
S
L
R
A
C
I
D
L
A
A
L
G
E
N
T
I
A
I
D
C
D
V
L
Q
A
D
G
G
T
R
T
A
A
I
T
G
A
Y
V
A
L
A
D
A
V
T
Y
L
S
A
A
G
K
L
S
-
D
P
R
P
L
S
C
A
I
A
A
V
S
V
G
V
--
V
--
D
-
G
R
I
R
V
D
L
P
Y
E
E
D
S
R
A
E
V
D
M
N
V
V
A
T
-
D
-
T
G
T
---
L
V
E
I
Q
G
--
T
G
E
G
A
T
F
A
R
S
T
L
D
K
L
L
D
M
A
L
G
A
C
D
T
L
F
A
A
Q
R
D
A
L
A
-
70
HHSearch
83.25
57%
-91
- C1 -
3B4T
2
RNPH_MYCTU
A:
[6-243]
-
K
R
E
D
G
R
L
D
H
E
L
R
P
V
I
I
T
R
G
F
T
E
N
P
A
G
S
V
L
I
E
F
G
H
T
K
V
L
C
T
A
S
V
T
E
G
V
-
P
-----
A
T
G
L
G
W
L
T
A
E
Y
A
M
L
P
S
A
T
H
S
R
S
D
R
E
S
V
R
G
R
L
S
G
R
T
Q
E
I
S
R
L
I
G
R
S
L
R
A
C
I
D
L
A
A
L
G
E
N
T
I
A
I
D
C
D
V
L
Q
A
D
G
G
T
R
T
A
A
I
T
G
A
Y
V
A
L
A
D
A
V
T
Y
L
S
A
A
G
K
L
S
D
P
-
R
P
L
S
C
A
I
A
A
V
S
V
G
V
--
V
--
D
-
G
R
I
R
V
D
L
P
Y
E
E
D
S
R
A
E
V
D
M
N
V
V
A
T
-
D
-
T
G
T
---
L
V
E
I
Q
G
--
T
G
E
G
A
T
F
A
R
S
T
L
D
K
L
L
D
M
A
L
G
A
C
D
T
L
F
A
A
Q
R
D
A
L
A
-
29
PsiBlast_CBE
83.16
56%
-101
- C1 -
1OYP
2
RNPH_BACSU
C:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
-----------------
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
11
PsiBlast_PDB
83.08
56%
-91
- C1 -
3B4T
2
RNPH_MYCTU
A:
[6-243]
-
K
R
E
D
G
R
L
D
H
E
L
R
P
V
I
I
T
R
G
F
T
E
N
P
A
G
S
V
L
I
E
F
G
H
T
K
V
L
C
T
A
S
V
T
E
G
V
-
P
-----
A
T
G
L
G
W
L
T
A
E
Y
A
M
L
P
S
A
T
H
S
R
S
D
R
E
S
V
R
G
R
L
S
G
R
T
Q
E
I
S
R
L
I
G
R
S
L
R
A
C
I
D
L
A
A
L
G
E
N
T
I
A
I
D
C
D
V
L
Q
A
D
G
G
T
R
T
A
A
I
T
G
A
Y
V
A
L
A
D
A
V
T
Y
L
S
A
A
G
K
L
S
-
D
P
R
P
L
S
C
A
I
A
A
V
S
V
G
V
--
V
--
D
-
G
R
I
R
V
D
L
P
Y
E
E
D
S
R
A
E
V
D
M
N
V
V
A
T
-
D
-
T
G
T
---
L
V
E
I
Q
G
--
T
G
E
G
A
T
F
A
R
S
T
L
D
K
L
L
D
M
A
L
G
A
C
D
T
L
F
A
A
Q
R
D
A
L
A
-
30
PsiBlast_CBE
83.03
56%
-102
- C1 -
1OYP
2
RNPH_BACSU
B:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
-----------------
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
3
PsiBlast_PDB
83.01
56%
-102
- C1 -
1OYP
2
RNPH_BACSU
A:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
-----------------
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
D
K
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
27
PsiBlast_CBE
82.65
56%
-101
- C1 -
1OYP
2
RNPH_BACSU
E:
[2-239]
--
R
H
D
G
R
Q
H
D
E
L
R
P
I
T
F
D
L
D
F
I
S
H
P
E
G
S
V
L
I
T
A
G
N
T
K
V
I
C
N
A
S
V
E
D
R
V
-
P
P
F
-
L
R
G
G
G
K
G
W
I
T
A
E
Y
S
M
L
-----------------
S
G
R
T
M
E
I
Q
R
L
I
G
R
A
L
R
A
V
V
D
L
E
K
L
G
E
R
T
I
W
I
D
C
D
V
I
Q
A
D
G
G
T
R
T
A
S
I
T
G
A
F
L
A
M
A
I
A
I
G
K
L
I
K
A
G
T
I
K
-
T
-
N
P
I
T
D
F
L
A
A
I
S
V
G
I
DK
E
--
Q
-
G
I
-
L
L
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
-
G
-
S
G
R
---
F
V
E
L
Q
G
--
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
D
K
Q
K
E
V
L
G
D
20
PsiBlast_PDB
68.06
30%
-90
- C1 -
2JEA
1
RRP41_SULSO
B:
[20-238]
-
K
R
T
D
G
R
K
P
D
E
L
R
S
I
K
I
E
L
G
V
L
K
N
A
D
G
S
A
I
F
E
M
G
N
T
K
A
I
A
A
V
Y
G
P
K
E
M
H
P
R
H
-
L
S
L
P
D
R
A
V
L
R
V
R
Y
H
M
T
P
F
S
T
D
E
R
K
N
P
A
P
S
R
-----
R
E
I
E
L
S
K
V
I
R
E
A
L
E
S
A
V
L
V
E
L
F
P
R
T
A
I
D
V
F
T
E
I
L
Q
A
D
A
G
S
R
L
V
S
L
M
A
A
S
L
A
L
A
D
A
------------
G
-
I
P
M
R
D
L
I
A
G
V
A
V
G
K
--
A
--
D
-
G
V
I
I
L
D
L
N
E
T
E
A
M
W
G
E
A
D
M
P
I
A
M
M
-
P
-
S
L
N
QVT
L
F
Q
L
N
G
--
S
-----
M
T
P
D
E
F
R
Q
A
F
D
L
A
V
K
G
I
N
I
I
Y
N
L
E
R
E
A
L
--
80
HHSearch
67.93
33%
-88
- C1 -
3M7N
1
RRP41_ARCFU
D:
[16-238]
-
L
R
L
D
G
R
K
F
D
E
L
R
P
I
K
I
E
A
S
V
L
K
R
A
D
G
S
C
Y
L
E
M
G
K
N
K
V
I
A
A
V
F
G
P
R
E
V
-
H
P
E
H
L
Q
D
P
S
K
A
I
I
R
Y
R
Y
N
M
A
P
F
S
V
E
E
R
K
R
-----
P
G
P
D
R
R
S
I
E
I
S
K
V
S
K
E
A
F
E
A
V
I
M
K
E
L
F
P
R
S
A
I
D
I
F
V
E
V
L
Q
A
D
A
G
S
R
T
A
C
L
N
A
A
S
V
A
L
V
D
A
------------
G
-
V
P
M
K
G
M
I
T
S
V
A
V
G
K
--
A
--
D
-
G
Q
L
V
L
D
P
M
K
E
E
D
N
F
G
E
A
D
M
P
F
A
F
L
I
R
-
N
G
K
IES
I
A
L
L
Q
M
--
D
G
---
R
M
T
R
D
E
V
K
Q
A
I
E
L
A
K
K
G
A
L
Q
I
Y
E
M
Q
R
E
A
I
L
-
72
HHSearch
67.00
33%
-86
- C1 -
2PO1
3
RRP41_PYRAB
A:
[16-236]
-
R
R
I
D
G
R
K
K
Y
E
L
R
P
I
K
M
E
V
G
V
L
K
N
A
N
G
S
A
Y
I
E
W
G
K
N
K
I
I
A
A
V
Y
G
P
R
E
L
-
H
P
K
H
L
Q
R
P
D
R
A
I
L
R
V
R
Y
N
M
A
P
F
S
V
E
E
R
K
K
-----
P
G
P
D
R
R
S
I
E
I
S
K
V
I
K
G
A
L
E
P
A
L
I
L
E
M
F
P
R
T
A
I
D
V
F
I
E
V
L
Q
A
D
A
G
T
R
V
A
G
I
T
A
A
S
L
A
L
A
D
A
------------
G
-
I
P
M
R
D
L
V
A
A
C
A
A
G
K
--
I
--
E
-
G
E
I
V
L
D
L
N
K
E
E
D
N
Y
G
E
A
D
V
P
V
A
I
M
-
P
L
K
N
D
---
I
T
L
L
Q
M
--
D
G
---
Y
L
T
K
D
E
F
I
E
A
V
K
L
A
I
K
G
A
K
A
V
Y
Q
K
Q
R
E
A
L
K
E
39
PsiBlast_CBE
66.57
32%
-79
- C1 -
3M7N
1
RRP41_ARCFU
F:
[17-237]
--
R
L
D
G
R
K
F
D
E
L
R
P
I
K
I
E
A
S
V
L
K
R
A
D
G
S
C
Y
L
E
M
G
K
N
K
V
I
A
A
V
F
G
P
R
E
V
H
P
E
H
-
L
Q
D
P
S
K
A
I
I
R
Y
R
Y
N
M
A
P
F
S
V
E
E
R
K
R
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
S
K
E
A
F
E
A
V
I
M
K
E
L
F
P
R
S
A
I
D
I
F
V
E
V
L
Q
A
D
A
G
S
R
T
A
C
L
N
A
A
S
V
A
L
V
D
A
------------
G
-
V
P
M
K
G
M
I
T
S
V
A
V
G
K
--
A
--
D
-
G
Q
L
V
L
D
P
M
K
E
E
D
N
F
G
E
A
D
M
P
F
A
F
L
-
I
-
R
N
G
---
K
I
E
S
I
A
LL
Q
M
D
G
R
M
T
R
-
D
E
V
K
Q
A
I
E
L
A
K
K
G
A
L
Q
I
Y
E
M
Q
R
E
A
I
--
36
PsiBlast_CBE
66.55
32%
-81
- C1 -
3M85
1
RRP41_ARCFU
F:
[17-237]
--
R
L
D
G
R
K
F
D
E
L
R
P
I
K
I
E
A
S
V
L
K
R
A
D
G
S
C
Y
L
E
M
G
K
N
K
V
I
A
A
V
F
G
P
R
E
V
H
P
E
H
-
L
Q
D
P
S
K
A
I
I
R
Y
R
Y
N
M
A
P
F
S
V
E
E
R
K
R
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
S
K
E
A
F
E
A
V
I
M
K
E
L
F
P
R
S
A
I
D
I
F
V
E
V
L
Q
A
D
A
G
S
R
T
A
C
L
N
A
A
S
V
A
L
V
D
A
------------
G
-
V
P
M
K
G
M
I
T
S
V
A
V
G
K
--
A
--
D
-
G
Q
L
V
L
D
P
M
K
E
E
D
N
F
G
E
A
D
M
P
F
A
F
L
-
I
-
R
N
G
---
K
I
E
S
I
A
LL
Q
M
D
G
R
M
T
R
-
D
E
V
K
Q
A
I
E
L
A
K
K
G
A
L
Q
I
Y
E
M
Q
R
E
A
I
--
41
PsiBlast_CBE
65.35
32%
-79
- C1 -
3M7N
1
RRP41_ARCFU
D:
[17-237]
--
R
L
D
G
R
K
F
D
E
L
R
P
I
K
I
E
A
S
V
L
K
R
A
D
G
S
C
Y
L
E
M
G
K
N
K
V
I
A
A
V
F
G
P
R
E
V
H
P
E
H
-
L
Q
D
P
S
K
A
I
I
R
Y
R
Y
N
M
A
P
F
S
V
E
E
R
K
R
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
S
K
E
A
F
E
A
V
I
M
K
E
L
F
P
R
S
A
I
D
I
F
V
E
V
L
Q
A
D
A
G
S
R
T
A
C
L
N
A
A
S
V
A
L
V
D
A
------------
G
-
V
P
M
K
G
M
I
T
S
V
A
V
G
K
--
A
--
D
-
G
Q
L
V
L
D
P
M
K
E
E
D
N
F
G
E
A
D
M
P
F
A
F
L
-
I
-
R
N
G
---
K
I
E
S
I
A
LL
Q
M
D
G
R
M
T
R
-
D
E
V
K
Q
A
I
E
L
A
K
K
G
A
L
Q
I
Y
E
M
Q
R
E
A
I
--
40
PsiBlast_CBE
65.30
32%
-75
- C1 -
3M7N
1
RRP41_ARCFU
E:
[17-237]
--
R
L
D
G
R
K
F
D
E
L
R
P
I
K
I
E
A
S
V
L
K
R
A
D
G
S
C
Y
L
E
M
G
K
N
K
V
I
A
A
V
F
G
P
R
E
V
H
P
E
H
-
L
Q
D
P
S
K
A
I
I
R
Y
R
Y
N
M
A
P
F
S
V
E
E
R
K
R
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
S
K
E
A
F
E
A
V
I
M
K
E
L
F
P
R
S
A
I
D
I
F
V
E
V
L
Q
A
D
A
G
S
R
T
A
C
L
N
A
A
S
V
A
L
V
D
A
------------
G
-
V
P
M
K
G
M
I
T
S
V
A
V
G
K
--
A
--
D
-
G
Q
L
V
L
D
P
M
K
E
E
D
N
F
G
E
A
D
M
P
F
A
F
L
-
I
-
R
N
G
---
K
I
E
S
I
A
LL
Q
M
D
G
R
M
T
R
-
D
E
V
K
Q
A
I
E
L
A
K
K
G
A
L
Q
I
Y
E
M
Q
R
E
A
I
--
38
PsiBlast_CBE
64.77
32%
-79
- C1 -
3M85
1
RRP41_ARCFU
D:
[17-237]
--
R
L
D
G
R
K
F
D
E
L
R
P
I
K
I
E
A
S
V
L
K
R
A
D
G
S
C
Y
L
E
M
G
K
N
K
V
I
A
A
V
F
G
P
R
E
V
H
P
E
H
-
L
Q
D
P
S
K
A
I
I
R
Y
R
Y
N
M
A
P
F
S
V
E
E
R
K
R
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
S
K
E
A
F
E
A
V
I
M
K
E
L
F
P
R
S
A
I
D
I
F
V
E
V
L
Q
A
D
A
G
S
R
T
A
C
L
N
A
A
S
V
A
L
V
D
A
------------
G
-
V
P
M
K
G
M
I
T
S
V
A
V
G
K
--
A
--
D
-
G
Q
L
V
L
D
P
M
K
E
E
D
N
F
G
E
A
D
M
P
F
A
F
L
-
I
-
R
N
G
---
K
I
E
S
I
A
LL
Q
M
D
G
R
M
T
R
-
D
E
V
K
Q
A
I
E
L
A
K
K
G
A
L
Q
I
Y
E
M
Q
R
E
A
I
--
45
PsiBlast_CBE
63.88
31%
-88
- C1 -
2PNZ
5
RRP41_PYRAB
A:
[17-236]
--
R
I
D
G
R
K
K
Y
E
L
R
P
I
K
M
E
V
G
V
L
K
N
A
N
G
S
A
Y
I
E
W
G
K
N
K
I
I
A
A
V
Y
G
P
R
E
L
H
P
K
H
-
L
Q
R
P
D
R
A
I
L
R
V
R
Y
N
M
A
P
F
S
V
E
E
R
K
K
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
I
K
G
A
L
E
P
A
L
I
L
E
M
F
P
R
T
A
I
D
V
F
I
E
V
L
Q
A
D
A
G
T
R
V
A
G
I
T
A
A
S
L
A
L
A
D
A
------------
G
-
I
P
M
R
D
L
V
A
A
C
A
A
G
K
--
I
--
E
-
G
E
I
V
L
D
L
N
K
E
E
D
N
Y
G
E
A
D
V
P
V
A
I
M
-
P
-
L
K
N
DIT
L
L
Q
M
D
G
--
Y
L
T
K
D
E
F
I
E
A
-----
V
K
L
A
I
K
G
A
K
A
V
Y
Q
K
Q
R
E
A
L
K
E
43
PsiBlast_CBE
63.83
31%
-90
- C1 -
2PO1
3
RRP41_PYRAB
A:
[17-236]
--
R
I
D
G
R
K
K
Y
E
L
R
P
I
K
M
E
V
G
V
L
K
N
A
N
G
S
A
Y
I
E
W
G
K
N
K
I
I
A
A
V
Y
G
P
R
E
L
H
P
K
H
-
L
Q
R
P
D
R
A
I
L
R
V
R
Y
N
M
A
P
F
S
V
E
E
R
K
K
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
I
K
G
A
L
E
P
A
L
I
L
E
M
F
P
R
T
A
I
D
V
F
I
E
V
L
Q
A
D
A
G
T
R
V
A
G
I
T
A
A
S
L
A
L
A
D
A
------------
G
-
I
P
M
R
D
L
V
A
A
C
A
A
G
K
--
I
--
E
-
G
E
I
V
L
D
L
N
K
E
E
D
N
Y
G
E
A
D
V
P
V
A
I
M
-
P
-
L
K
N
DIT
L
L
Q
M
D
G
--
Y
L
T
K
D
E
F
I
E
A
-----
V
K
L
A
I
K
G
A
K
A
V
Y
Q
K
Q
R
E
A
L
K
E
37
PsiBlast_CBE
63.83
32%
-80
- C1 -
3M85
1
RRP41_ARCFU
E:
[17-237]
--
R
L
D
G
R
K
F
D
E
L
R
P
I
K
I
E
A
S
V
L
K
R
A
D
G
S
C
Y
L
E
M
G
K
N
K
V
I
A
A
V
F
G
P
R
E
V
H
P
E
H
-
L
Q
D
P
S
K
A
I
I
R
Y
R
Y
N
M
A
P
F
S
V
E
E
R
K
R
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
S
K
E
A
F
E
A
V
I
M
K
E
L
F
P
R
S
A
I
D
I
F
V
E
V
L
Q
A
D
A
G
S
R
T
A
C
L
N
A
A
S
V
A
L
V
D
A
------------
G
-
V
P
M
K
G
M
I
T
S
V
A
V
G
K
--
A
--
D
-
G
Q
L
V
L
D
P
M
K
E
E
D
N
F
G
E
A
D
M
P
F
A
F
L
-
I
-
R
N
G
---
K
I
E
S
I
A
LL
Q
M
D
G
R
M
T
R
-
D
E
V
K
Q
A
I
E
L
A
K
K
G
A
L
Q
I
Y
E
M
Q
R
E
A
I
--
42
PsiBlast_CBE
63.54
31%
-89
- C1 -
2PO2
3
RRP41_PYRAB
A:
[17-236]
--
R
I
D
G
R
K
K
Y
E
L
R
P
I
K
M
E
V
G
V
L
K
N
A
N
G
S
A
Y
I
E
W
G
K
N
K
I
I
A
A
V
Y
G
P
R
E
L
H
P
K
H
-
L
Q
R
P
D
R
A
I
L
R
V
R
Y
N
M
A
P
F
S
V
E
E
R
K
K
P
G
P
D
R
-----
R
S
I
E
I
S
K
V
I
K
G
A
L
E
P
A
L
I
L
E
M
F
P
R
T
A
I
D
V
F
I
E
V
L
Q
A
D
A
G
T
R
V
A
G
I
T
A
A
S
L
A
L
A
D
A
------------
G
-
I
P
M
R
D
L
V
A
A
C
A
A
G
K
--
I
--
E
-
G
E
I
V
L
D
L
N
K
E
E
D
N
Y
G
E
A
D
V
P
V
A
I
M
-
P
-
L
K
N
DIT
L
L
Q
M
D
G
--
Y
L
T
K
D
E
F
I
E
A
-----
V
K
L
A
I
K
G
A
K
A
V
Y
Q
K
Q
R
E
A
L
K
E