@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA5546: (2016-03-08 )
MIAQLPSELLSLQLPLRIRIGDAQAFDLGPDPQVTMVIRDPSLLTEITHPSLDALGKAYVEKRLDIEGPISQVIGIGDALSEALGEPDGGAPPVRESHDKDTDAEAIHYHYDLSNDFYQLWLDPEMVYSCAYFETGKEDLATAQLAKLRHLCRKLRLQPGEKLLDVGCGWGGLARLAAREFGVEVTGITLSKEQLALGRERVKAEGLEDRVTLKLLDYRDLPRDGRFDKVVSVGMFEHVGHANLGLYFQQLYEAVRPGGLVMNHGITSRYTDGRPVGKGAGDFIDRYVFPHGELPHLSLAVARMSEAGLEVVDVESLRLHYARTLDFWSANLEARLKEAARLVPEETLRIWRLYLAGCAYGFKRGWINLHQILAIRPHEDGSHELPWSRRDLYA
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200-.....-..-210.......220.-...------------...230......-------.240.-------......250.......-260.....--------.-.270-----...--------.--------...280-----.---------........290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MIAQL
P
S
E
L
L
SLQL
P
L
R
I
R
IGDAQAFDLGPDP
Q
V
T
M
V
IRD
P
S
L
L
T
E
ITHP
S
L
D
A
L
G
K
A
Y
V
E
K
RLDIEG
P
I
S
Q
V
IG
I
G
D
A
L
S
E
A
LGEPDGGAPPVRESHDKDTDA
E
A
I
H
Y
H
YDLSN
D
F
Y
Q
LWL
D
P
E
M
V
Y
S
C
A
Y
FETGK
E
D
L
A
T
A
Q
L
A
K
L
R
H
L
C
R
K
LRLQPGE
K
L
L
DVGCG
W
G
G
L
A
R
L
A
A
R
E
FG
V
E
V
T
G
I
T
L
S
K
E
Q
L
A
L
G
R
E
R
V
-
K
AEGL-ED-
R
V
T
L
K
L
LDYRDLPR-DGR------------F
D
K
V
V
S
V
G
M
F
E
H-------VGH
A
N
-------
L
G
L
Y
F
Q
Q
L
Y
E
A
VRPG
G
-
L
V
MNHGIT--------S-RYTD-----GRP--------V--------GK
G
A
-------
G
---------
D
F
I
D
R
YVFPHGEL
P
H
L
S
L
A
V
A
R
M
S
EAG
L
E
V
V
D
V
E
S
L
R
L
H
Y
A
R
T
L
D
F
W
S
A
N
L
E
A
R
L
K
E
A
A
RLV
P
E
E
T
L
R
I
W
R
L
Y
L
A
G
C
A
Y
G
F
KRG
W
I
N
L
H
Q
I
L
A
IRPHEDGSHELPWSRRDLYA
6
PsiBlast_PDB
90.20
33%
-99
- C2 -
1KPI
7
CMAS2_MYCTU
A:
[18-302]
--------------------------------------------------------------------------------------------------------
E
A
V
R
S
H
Y
D
K
S
N
E
F
F
K
L
W
L
D
P
S
M
T
Y
S
C
A
Y
F
E
R
P
D
M
T
L
E
E
A
Q
Y
A
K
R
K
L
A
L
D
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
S
T
M
R
H
A
V
A
E
Y
D
V
N
V
I
G
L
T
L
S
E
N
Q
Y
A
H
D
K
A
M
F
-
D
E
V
D
S
-
P
R
-
R
K
E
V
R
I
Q
G
W
E
E
F
---
D
E
P
------------
V
D
R
I
V
S
L
G
A
F
E
H
FADGAGD
A
G
F
E
R
-------
Y
D
T
F
F
K
K
F
Y
N
L
T
P
D
D
G
-
R
M
L
L
H
T
I
T
I
-------
P
-
D
K
E
E
-----
A
Q
E
--------
L
--------
G
L
T
S
-------
P
M
S
L
L
R
F
I
--
K
F
I
L
T
E
I
F
P
G
G
R
L
P
R
I
S
Q
V
D
Y
Y
S
S
N
A
G
W
K
V
E
R
Y
H
R
I
G
A
N
Y
V
P
T
L
N
A
W
A
D
A
L
Q
A
H
K
D
E
A
I
A
L
K
G
Q
E
T
C
D
I
Y
M
H
Y
L
R
G
C
S
D
L
F
R
D
K
Y
T
D
V
C
Q
F
T
L
V
K
------------------
116
HHSearch
88.21
34%
-92
- C2 -
3HEM
2
CMAS2_MYCTU
A:
[12-302]
--------------------------------------------------------------------------------------------------
Q
L
K
P
P
V
E
A
V
R
S
H
Y
D
K
S
N
E
F
F
K
L
W
L
D
P
S
M
T
Y
S
C
A
Y
F
E
R
P
D
M
T
L
E
E
A
Q
Y
A
K
R
K
L
A
L
D
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
S
T
M
R
H
A
V
A
E
Y
D
V
N
V
I
G
L
T
L
S
E
N
Q
Y
A
H
D
K
A
M
F
-
D
E
V
D
S
-
P
R
-
R
K
E
V
R
I
Q
G
W
E
E
F
---
D
E
P
------------
V
D
R
I
V
S
L
G
A
F
E
H
-------
F
A
D
G
A
GDAGF
E
R
Y
D
T
F
F
K
K
F
Y
N
L
T
P
D
D
G
-
R
M
L
L
H
T
I
T
--------
I
-
P
D
K
E
-----
E
A
Q
E
L
G
L
T
S
P
M
S
--------
L
L
R
F
-------
I
---------
K
F
I
L
T
E
I
F
P
G
G
R
L
P
R
I
S
Q
V
D
Y
Y
S
S
N
A
G
W
K
V
E
R
Y
H
R
I
G
A
N
Y
V
P
T
L
N
A
W
A
D
A
L
Q
A
H
K
D
E
A
I
A
L
K
G
Q
E
T
C
D
I
Y
M
H
Y
L
R
G
C
S
D
L
F
R
D
K
Y
T
D
V
C
Q
F
T
L
V
K
------------------
7
PsiBlast_PDB
88.04
33%
-93
- C2 -
3HEM
2
CMAS2_MYCTU
A:
[18-302]
--------------------------------------------------------------------------------------------------------
E
A
V
R
S
H
Y
D
K
S
N
E
F
F
K
L
W
L
D
P
S
M
T
Y
S
C
A
Y
F
E
R
P
D
M
T
L
E
E
A
Q
Y
A
K
R
K
L
A
L
D
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
S
T
M
R
H
A
V
A
E
Y
D
V
N
V
I
G
L
T
L
S
E
N
Q
Y
A
H
D
K
A
M
F
-
D
E
V
D
S
-
P
R
-
R
K
E
V
R
I
Q
G
W
E
E
F
---
D
E
P
------------
V
D
R
I
V
S
L
G
A
F
E
H
FADGAGD
A
G
F
E
R
-------
Y
D
T
F
F
K
K
F
Y
N
L
T
P
D
D
G
-
R
M
L
L
H
T
I
T
I
-------
P
-
D
K
E
E
-----
A
Q
E
--------
L
--------
G
L
T
S
-------
P
M
S
L
L
R
F
I
--
K
F
I
L
T
E
I
F
P
G
G
R
L
P
R
I
S
Q
V
D
Y
Y
S
S
N
A
G
W
K
V
E
R
Y
H
R
I
G
A
N
Y
V
P
T
L
N
A
W
A
D
A
L
Q
A
H
K
D
E
A
I
A
L
K
G
Q
E
T
C
D
I
Y
M
H
Y
L
R
G
C
S
D
L
F
R
D
K
Y
T
D
V
C
Q
F
T
L
V
K
------------------
22
PsiBlast_CBE
87.51
39%
-97
- C2 -
1KPH
3
CMAS1_MYCTU
C:
[12-283]
----------------------------------------------------------------------------------------------------------
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
-
R
V
L
L
A
G
W
E
Q
F
D
E
P
-----------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
EIHER
G
L
P
--------
M
--------
S
F
T
F
-------
A
RFL------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
----------------------
21
PsiBlast_CBE
87.27
39%
-96
- C2 -
1KPH
3
CMAS1_MYCTU
D:
[12-283]
----------------------------------------------------------------------------------------------------------
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
-
R
V
L
L
A
G
W
E
Q
F
D
E
P
-----------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
EIHER
G
L
P
--------
M
--------
S
F
T
F
-------
A
RFL------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
----------------------
2
PsiBlast_PDB
87.07
39%
-96
- C2 -
1KPH
3
CMAS1_MYCTU
A:
[12-283]
----------------------------------------------------------------------------------------------------------
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
-
R
V
L
L
A
G
W
E
Q
F
D
E
P
-----------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
EIHER
G
L
P
--------
M
--------
S
F
T
F
-------
A
R
F
L
------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
----------------------
3
PsiBlast_PDB
86.62
39%
-96
- C2 -
1KPG
3
CMAS1_MYCTU
A:
[12-283]
----------------------------------------------------------------------------------------------------------
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
-
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
-----------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
E
I
H
E
R
G
L
P
--------
M
--------
S
F
T
F
-------
A
R
F
L
------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
----------------------
23
PsiBlast_CBE
86.10
39%
-97
- C2 -
1KPH
3
CMAS1_MYCTU
B:
[12-283]
----------------------------------------------------------------------------------------------------------
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
-
R
V
L
L
A
G
W
E
Q
F
D
E
P
-----------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
E
I
H
E
R
G
L
P
--------
M
--------
S
F
T
F
-------
A
R
F
L
------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
----------------------
117
HHSearch
85.09
37%
-88
- C2 -
1KPG
3
CMAS1_MYCTU
A:
[3-287]
-------------------------------------------------------------------------------------------------
D
E
L
K
P
H
F
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
-
A
N
S
E
-----
N
L
R
S
K
R
V
L
L
A
G
W
E
Q
F
D
E
P
------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
-----
E
I
H
--------
E
R
GLPM
S
F
T
F
A
R
F
-------
L
---------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
------------------
1
PsiBlast_PDB
85.08
39%
-98
- C2 -
1KP9
1
CMAS1_MYCTU
A:
[18-283]
----------------------------------------------------------------------------------------------------------------
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
-
R
V
L
L
A
G
W
E
Q
F
D
E
P
-----------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
EIHER
G
L
P
--------
M
--------
S
F
T
F
-------
A
R
F
L
------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
----------------------
24
PsiBlast_CBE
84.99
39%
-98
- C2 -
1KP9
2
CMAS1_MYCTU
B:
[18-283]
----------------------------------------------------------------------------------------------------------------
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
A
N
S
E
N
L
R
S
K
-
R
V
L
L
A
G
W
E
Q
F
D
E
P
-----------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
--------
G
-
L
H
P
K
EIHER
G
L
P
--------
M
--------
S
F
T
F
-------
A
RFL------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
----------------------
107
Fugue
84.88
37%
-90
- C2 -
1KPH
3
CMAS1_MYCTU
A:
[5-287]
---------------------------------------------------------------------------------------------------
L
K
P
H
F
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
-
A
N
S
E
N
-
L
R
-
S
K
R
V
L
L
A
G
W
E
Q
F
---
D
E
P
------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
G
L
HPKEIH
E
-
R
G
L
P
-----
M
S
F
--------
T
--------
F
A
R
F
-------
L
---------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
------------------
105
Fugue
84.88
37%
-90
- C2 -
1KPH
3
CMAS1_MYCTU
A:
[5-287]
---------------------------------------------------------------------------------------------------
L
K
P
H
F
A
N
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
V
G
C
G
W
G
A
T
M
M
R
A
V
E
K
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
N
H
V
Q
Q
L
V
-
A
N
S
E
N
-
L
R
-
S
K
R
V
L
L
A
G
W
E
Q
F
---
D
E
P
------------
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
E
R
-------
Y
D
A
F
F
S
L
A
H
R
L
L
P
A
D
G
-
V
M
L
L
H
T
I
T
G
L
HPKEIH
E
-
R
G
L
P
-----
M
S
F
--------
T
--------
F
A
R
F
-------
L
---------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
I
P
M
V
Q
E
C
A
S
A
N
G
F
T
V
T
R
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
------------------
4
PsiBlast_PDB
84.73
35%
-91
- C2 -
1TPY
3
MMAA2_MYCTU
A:
[10-283]
--------------------------------------------------------------------------------------------------------
E
D
V
Q
A
H
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
H
F
E
R
E
D
M
T
L
E
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
G
L
Q
P
G
M
T
L
L
D
I
G
C
G
W
G
A
T
M
R
R
A
I
A
Q
Y
D
V
N
V
V
G
L
T
L
S
K
N
Q
A
A
H
V
Q
-----------------
K
S
F
D
E
M
D
T
P
R
-
D
R
R
V
L
LAGWEQ
F
N
E
P
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
D
R
-------
H
A
D
F
F
A
R
A
H
K
I
L
P
P
D
G
-
V
L
L
L
H
T
I
T
--------
G
--
L
T
R
-----
Q
Q
M
--------
V
--------
D
H
G
L
-------
P
LT
L
W
L
A
R
F
L
K
F
I
A
T
E
I
F
P
G
G
Q
P
P
T
I
E
M
V
E
E
Q
S
A
K
T
G
F
T
L
T
R
R
Q
S
L
Q
P
H
Y
A
R
T
L
D
L
W
A
E
A
L
Q
E
H
K
S
E
A
I
A
I
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
K
L
F
R
V
G
Y
I
D
V
N
Q
F
----------------------
9
PsiBlast_PDB
84.01
32%
-93
- C2 -
2FK8
1
MMAA4_MYCTU
A:
[38-314]
----------------------------------------------------------------------------------------------------------
I
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
-
A
S
I
D
T
-
N
R
-
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
-
P
--------------
V
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
S
--------
Y
-
H
P
Y
E
-----
M
A
A
--------
R
--------
G
K
K
L
-------
S
F
E
T
A
R
F
I
--
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
-----------------
8
PsiBlast_PDB
83.90
32%
-94
- C2 -
2FK7
-
MMAA4_MYCTU
A:
[22-297]
-----------------------------------------------------------------------------------------------------------
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
-
A
S
I
D
T
-
N
R
-
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
-
P
--------------
V
D
R
I
V
S
I
E
A
F
E
H
----------
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
S
--------
Y
-
H
P
Y
E
-----
M
A
A
--------
R
--------
G
K
K
L
-------
S
F
E
T
A
R
F
I
--
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
-----------------
115
HHSearch
83.71
33%
-88
- C2 -
2FK8
1
MMAA4_MYCTU
A:
[38-317]
----------------------------------------------------------------------------------------------------------
I
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
-
A
S
I
D
T
-
N
R
-
S
R
Q
V
L
L
Q
G
W
E
D
F
---
A
E
P
------------
V
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
-
R
M
T
V
Q
S
S
V
--------
S
-
Y
H
P
Y
-----
E
M
A
--------
A
R
G
K
K
L
S
F
E
T
A
R
F
-------
I
---------
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
G
A
A
--------------
11
PsiBlast_PDB
83.67
32%
-95
- C2 -
3HA5
1
MMAA4_MYCTU
A:
[38-314]
----------------------------------------------------------------------------------------------------------
I
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
-
A
S
I
D
T
-
N
R
-
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
-
P
--------------
V
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
S
--------
Y
-
H
P
Y
E
-----
M
A
A
--------
R
--------
G
K
K
L
-------
S
F
E
T
A
R
F
I
--
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
-----------------
10
PsiBlast_PDB
83.29
32%
-94
- C2 -
3HA3
1
MMAA4_MYCTU
A:
[38-314]
----------------------------------------------------------------------------------------------------------
I
Q
A
H
Y
D
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
-
A
S
I
D
T
-
N
R
-
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
-
P
--------------
V
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
S
--------
Y
-
H
P
Y
E
-----
M
A
A
--------
R
--------
G
K
K
L
-------
S
F
E
T
A
R
F
I
--
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
T
S
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
-----------------
5
PsiBlast_PDB
82.09
34%
-96
- C2 -
1L1E
2
CMAS3_MYCTU
A:
[16-283]
--------------------------------------------------------------------------------------------------------------
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
A
T
M
R
R
A
I
E
K
Y
D
V
N
V
V
G
L
T
L
S
E
N
Q
A
G
H
V
Q
-----------------
K
M
F
D
Q
M
D
T
P
R
-
S
R
R
V
L
LEGWEK
F
D
E
P
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
Q
R
-------
Y
H
H
F
F
E
V
T
H
R
T
L
P
A
D
G
-
K
M
L
L
H
T
I
V
--------
R
P
T
F
K
E
-----
G
R
E
--------
K
--------
G
L
T
L
THEL
V
H
F
T
---------
K
F
I
L
A
E
I
F
P
G
G
W
L
P
S
I
P
T
V
H
E
Y
A
E
K
V
G
F
R
V
T
A
V
Q
S
L
Q
L
H
Y
A
R
T
L
D
M
W
A
T
A
L
E
A
N
K
D
Q
A
I
A
I
Q
S
Q
T
V
Y
D
R
Y
M
K
Y
L
T
G
C
A
K
L
F
R
Q
G
Y
T
D
V
D
Q
F
----------------------
25
PsiBlast_CBE
81.13
34%
-95
- C2 -
1L1E
2
CMAS3_MYCTU
B:
[16-283]
--------------------------------------------------------------------------------------------------------------
Y
D
L
S
D
D
F
F
R
L
F
L
D
P
T
Q
T
Y
S
C
A
Y
F
E
R
D
D
M
T
L
Q
E
A
Q
I
A
K
I
D
L
A
L
G
K
L
N
L
E
P
G
M
T
L
L
D
I
G
C
G
W
G
A
T
M
R
R
A
I
E
K
Y
D
V
N
V
V
G
L
T
L
S
E
N
Q
A
G
H
V
Q
-----------------
K
M
F
D
Q
M
D
T
P
R
-
S
R
R
V
L
LEGWEK
F
D
E
P
V
D
R
I
V
S
I
G
A
F
E
H
-------
F
G
H
Q
R
-------
Y
H
H
F
F
E
V
T
H
R
T
L
P
A
D
G
-
K
M
L
L
H
T
I
V
--------
R
P
T
F
K
------------------------------LVH
F
---
T
---------
K
F
I
L
A
E
I
F
P
G
G
W
L
P
S
I
P
T
V
H
E
Y
A
E
K
V
G
F
R
V
T
A
V
Q
S
L
Q
L
H
Y
A
R
T
L
D
M
W
A
T
A
L
E
A
N
K
D
Q
A
I
A
I
Q
S
Q
T
V
Y
D
R
Y
M
K
Y
L
T
G
C
A
K
L
F
R
Q
G
Y
T
D
V
D
Q
F
----------------------
12
PsiBlast_PDB
80.65
32%
-96
- C2 -
3HA7
1
MMAA4_MYCTU
A:
[44-314]
----------------------------------------------------------------------------------------------------------------
V
S
D
D
F
F
A
L
F
Q
D
P
T
R
T
Y
S
C
A
Y
F
E
P
P
E
L
T
L
E
E
A
Q
Y
A
K
V
D
L
N
L
D
K
L
D
L
K
P
G
M
T
L
L
D
I
G
C
G
W
G
T
T
M
R
R
A
V
E
R
F
D
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
-
A
S
I
D
T
-
N
R
-
S
R
Q
V
L
L
Q
G
W
E
D
F
A
E
-
P
--------------
V
D
R
I
V
S
I
E
A
F
E
H
-------
F
G
H
E
N
-------
Y
D
D
F
F
K
R
C
F
N
I
M
P
A
D
G
R
M
T
V
Q
S
S
V
S
--------
Y
-
H
P
Y
E
-------
A
--------
R
--------
G
K
K
L
-------
S
F
E
T
A
R
F
I
--
K
F
I
V
T
E
I
F
P
G
G
R
L
P
S
T
E
M
M
V
E
H
G
E
K
A
G
F
T
V
P
E
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
V
--
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
-----------------