@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Comparative Docking Tab: Displays ligands Score after transfer from template to model
Cell color: RMS between binding site of experimental template and receptor: [‹ 3Å | ‹ 10Å | › 10Å]
Result: [ Good | Correct | Acceptable | Bad | Empty = ligand not selected during the calculation step or result rejected ]

Query sequence : ALK_HUMAN: (2013-07-19 )
MGAIGLLWLLPLLLSTAAVGSGMGTGQRAGSPAAGPPLQPREPLSYSRLQRKSLAVDFVVPSLFRVYARDLLLPPSSSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPAPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPGEAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQIFGTGHSSLESPTNMPSPSPDYFTWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRIPSEEASQMDLLDGPGAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGWTQGTLSPHTPQWQVRTLKDARFQDHQDHALLLSTTDVPASESATVTSATFPAPIKSSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKILQNTAPKSRNLFERNPNKELKPGENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP

Atome Classification :

(68 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

GUI_A_2(2XB7)

[Raw transfer]




LGV_A_2(3NW7)

[Raw transfer]




ANP_A_3(2OZO)
ZAP70_HUMAN
[Raw transfer]




LGW_A_2(3NW6)

[Raw transfer]




EBI_A_2(3I81)

[Raw transfer]




0JF_B_4(4DCE)

[Raw transfer]




LGX_A_2(3NW5)

[Raw transfer]




I3K_A_2(4FNY)

[Raw transfer]




NZF_A_2(4FNZ)

[Raw transfer]




ANP_A_2(4FL3)
KSYK_HUMAN
[Raw transfer]




GOL_A_2(3L9P)

[Raw transfer]




GOL_A_2(3L9P)

[Raw transfer]




0US_A_2(4FOB)

[Raw transfer]




CKJ_B_7(3TCP)

[Raw transfer]




V4Z_C_10(4AOJ)

[Raw transfer]




351_B_4(3ETA)

[Raw transfer]




0S9_B_18(4F65)

[Raw transfer]




V4Z_B_7(4AOJ)
NTRK1_HUMAN
[Raw transfer]




0UU_A_2(4FOC)

[Raw transfer]




STU_A_2(3LCS)

[Raw transfer]




1BQ_A_2(4I4E)

[Raw transfer]




351_A_3(3ETA)
INSR_HUMAN
[Raw transfer]




0JF_A_3(4DCE)
ALK_HUMAN
[Raw transfer]




0F4_A_4(3V5Q)
NTRK3_HUMAN
[Raw transfer]




ABG_A_7(2PWL)
FGFR2_HUMAN
[Raw transfer]




ADP_A_3(3LCT)

[Raw transfer]




01P_A_5(3QQU)
IGF1R_HUMAN
[Raw transfer]




01P_D_8(3QQU)

[Raw transfer]




M33_A_7(3B2T)
FGFR2_HUMAN
[Raw transfer]




GS2_A_2(3EKK)

[Raw transfer]




01P_B_6(3QQU)
IGF1R_HUMAN
[Raw transfer]




0UV_A_2(4FOD)

[Raw transfer]




EMH_A_2(3AOX)

[Raw transfer]




0S7_B_6(4F63)

[Raw transfer]




ACP_A_3(1I44)

[Raw transfer]




STU_A_13(3BKB)

[Raw transfer]




V4Z_A_4(4AOJ)
NTRK1_HUMAN
[Raw transfer]




CKJ_A_3(3TCP)
MERTK_HUMAN
[Raw transfer]




ABG_B_8(2PWL)
FGFR2_HUMAN
[Raw transfer]




STU_A_3(3CBL)

[Raw transfer]




BMI_B_2(2OJ9)

[Raw transfer]




C4F_B_4(3C4F)

[Raw transfer]




C4F_A_3(3C4F)
FGFR1_HUMAN
[Raw transfer]




MUJ_A_2(4AT5)

[Raw transfer]




GS3_A_2(3EKN)

[Raw transfer]




01P_C_7(3QQU)
IGF1R_HUMAN
[Raw transfer]




P16_A_3(1OPK)
ABL1_MOUSE
[Raw transfer]




SU1_B_3(1FGI)

[Raw transfer]




ANP_B_9(1JQH)
IGF1R_HUMAN
[Raw transfer]




0VF_A_2(4FYO)

[Raw transfer]




LTI_A_2(4AT3)

[Raw transfer]




GQL_B_5(3GQL)
FGFR1_HUMAN
[Raw transfer]




GQL_A_4(3GQL)
FGFR1_HUMAN
[Raw transfer]




PDR_A_5(3LVP)
IGF1R_HUMAN
[Raw transfer]




VGH_A_2(3ZBF)
?
[Raw transfer]




PP1_B_2(1QCF)
HCK_HUMAN
[Raw transfer]




T6E_A_2(4AT4)

[Raw transfer]




5CN_A_2(2I0Y)

[Raw transfer]




M33_B_8(3B2T)

[Raw transfer]




6C3_A_3(2I0V)

[Raw transfer]




ADP_B_11(3BRB)

[Raw transfer]




VM1_A_3(3JS2)
FGFR1_HUMAN
[Raw transfer]




EDO_A_4(4F63)
FGFR1_HUMAN
[Raw transfer]




EDO_B_7(4F63)

[Raw transfer]




EDO_B_8(4F64)

[Raw transfer]




EDO_A_4(4F64)
FGFR1_HUMAN
[Raw transfer]




CCX_D_13(3LW0)

[Raw transfer]




CCX_A_5(3LW0)
IGF1R_HUMAN
[Raw transfer]




CCX_B_7(3LW0)
IGF1R_HUMAN
[Raw transfer]




CCX_C_10(3LW0)
IGF1R_HUMAN
[Raw transfer]




3 PsiBlast_PDB 93.50100%-105 - C1 -3AOX 8.7
8 PsiBlast_PDB 92.9599%-101 - C1 -4FOD 10.1
6 PsiBlast_PDB 92.7399%-103 - C1 -3LCS 8.9
23 PsiBlast_CBE 92.49100%-102 - C1 -2XB7 8.0
7 PsiBlast_PDB 92.4899%-101 - C1 -4DCE 9.6 ALK_HUMAN
2 PsiBlast_PDB 92.1799%-102 - C1 -4FOC 8.1
21 PsiBlast_CBE 91.2799%-104 - C1 -4DCE 9.9
120 HHSearch 91.2599% -99 - C1 -3L9P 2.6
5 PsiBlast_PDB 90.6599% -99 - C1 -3LCT 3.8
1 PsiBlast_PDB 90.2699%-102 - C1 -4FOB 8.7
9 PsiBlast_PDB 90.1599% -99 - C1 -4FNZ 10.1
11 PsiBlast_PDB 88.8799%-104 - C1 -4FNY 10.3
119 HHSearch 68.3143% -89 - C1 -4AOJ 7.6 NTRK1_HUMAN
50 PsiBlast_CBE 67.5340% -85 - C1 -4AOJ 7.5
39 PsiBlast_CBE 66.3345% -82 - C1 -3LW0 5.6 IGF1R_HUMAN
42 PsiBlast_CBE 66.3043% -75 - C1 -3ETA 11.9 INSR_HUMAN
51 PsiBlast_CBE 66.1040% -85 - C1 -4AOJ 6.8 NTRK1_HUMAN
38 PsiBlast_CBE 65.7345% -82 - C1 -3LW0 5.4 IGF1R_HUMAN
127 HHSearch 65.6244% -86 - C1 -3CBL 8.3
26 PsiBlast_CBE 65.5344% -80 - C1 -1JQH 4.2 IGF1R_HUMAN
36 PsiBlast_CBE 65.3745% -83 - C1 -3LW0 5.6
99 PsiBlast_CBE 65.1938% -83 - C1 -2I0V 7.9
31 PsiBlast_CBE 65.1545% -81 - C1 -3NW7 8.5
41 PsiBlast_CBE 64.7643% -75 - C1 -3ETA 11.9
121 HHSearch 64.6137% -89 * C1 *4I4E 6.3
32 PsiBlast_CBE 64.3845% -83 - C1 -3NW6 8.1
37 PsiBlast_CBE 64.3645% -81 - C1 -3LW0 5.3 IGF1R_HUMAN
98 PsiBlast_CBE 64.2838% -81 - C1 -2I0Y 7.5
33 PsiBlast_CBE 64.1345% -84 - C1 -3NW5 7.0
83 PsiBlast_CBE 63.9137% -90 - C1 -2PWL 4.8 FGFR2_HUMAN
24 PsiBlast_CBE 63.7449% -91 - C1 -3ZBF 6.9 ?
65 PsiBlast_CBE 63.3939% -92 - C1 -4F65 7.3
34 PsiBlast_CBE 63.1245% -80 - C1 -2OJ9 7.8
35 PsiBlast_CBE 62.9845% -85 - C1 -3I81 7.7
135 HHSearch 62.8935% -81 - C1 -4FL3 5.8 KSYK_HUMAN
73 PsiBlast_CBE 62.6139% -89 - C1 -1FGI 6.6
84 PsiBlast_CBE 62.5337% -88 - C1 -2PWL 5.1 FGFR2_HUMAN
79 PsiBlast_CBE 62.4439% -90 - C1 -3C4F 6.4
25 PsiBlast_CBE 62.3743% -88 - C1 -3LVP 5.9 IGF1R_HUMAN
29 PsiBlast_CBE 61.9945% -80 - C1 -3QQU 6.7 IGF1R_HUMAN
64 PsiBlast_CBE 61.9139% -85 - C1 -3JS2 4.3 FGFR1_HUMAN
43 PsiBlast_CBE 61.8445% -78 - C1 -1I44 5.1
102 PsiBlast_CBE 61.7437% -90 - C1 -3B2T 4.3 FGFR2_HUMAN
57 PsiBlast_CBE 61.3838% -79 - C1 -3GQL 5.8 FGFR1_HUMAN
30 PsiBlast_CBE 60.9845% -83 - C1 -3QQU 6.8 IGF1R_HUMAN
27 PsiBlast_CBE 60.7545% -84 - C1 -3QQU 7.0
45 PsiBlast_CBE 60.6145% -81 - C1 -3EKN 7.3
68 PsiBlast_CBE 60.0139% -92 - C1 -4F64 2.6 FGFR1_HUMAN
58 PsiBlast_CBE 59.9838% -79 - C1 -3GQL 6.2 FGFR1_HUMAN
28 PsiBlast_CBE 59.8845% -79 - C1 -3QQU 8.1 IGF1R_HUMAN
46 PsiBlast_CBE 59.7345% -83 - C1 -3EKK 7.4
67 PsiBlast_CBE 59.7039% -89 - C1 -4F64 2.6
80 PsiBlast_CBE 59.5939% -89 - C1 -3C4F 6.7 FGFR1_HUMAN
48 PsiBlast_CBE 59.5842% -79 - C1 -4AT4 7.7
70 PsiBlast_CBE 59.2239% -91 - C1 -4F63 1.8 FGFR1_HUMAN
47 PsiBlast_CBE 59.0842% -78 - C1 -4AT5 7.4
132 HHSearch 59.0634% -85 - C1 -2OZO 5.6 ZAP70_HUMAN
49 PsiBlast_CBE 59.0142% -77 - C1 -4AT3 5.6
101 PsiBlast_CBE 58.9137% -91 - C1 -3B2T 4.1
55 PsiBlast_CBE 58.8942% -88 - C1 -3BKB 8.5
69 PsiBlast_CBE 58.7439% -86 - C1 -4F63 5.7
122 HHSearch 58.6235% -90 - C1 -4FYO 6.3
103 PsiBlast_CBE 56.7337% -93 - C1 -3TCP 6.6
53 PsiBlast_CBE 56.6540% -83 - C1 -3V5Q 8.1 NTRK3_HUMAN
133 HHSearch 56.1140% -82 - C1 -1OPK 9.2 ABL1_MOUSE
131 HHSearch 55.7339% -85 - C1 -1QCF 5.3 HCK_HUMAN
104 PsiBlast_CBE 53.9137%-100 - C1 -3TCP 6.5 MERTK_HUMAN
105 PsiBlast_CBE 53.5137% -93 - C1 -3BRB 4.0