@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Comparative Docking Tab: Displays ligands Score after transfer from template to model
Cell color: RMS between binding site of experimental template and receptor: [‹ 3Å | ‹ 10Å | › 10Å]
Result: [ Good | Correct | Acceptable | Bad | Empty = ligand not selected during the calculation step or result rejected ]

Query sequence : CSF1R_HUMAN: (2015-06-17 )
MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSNDSFSEQDLDKEDGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTNLPSSSRSGGSGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC

Atome Classification :

(87 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

STI_A_4(1T46)

[Raw transfer]




C19_B_4(3CP9)

[Raw transfer]




706_B_4(3EFL)

[Raw transfer]




276_A_2(2QU5)

[Raw transfer]




C92_A_3(3CPB)
VGFR2_HUMAN
[Raw transfer]




C92_B_4(3CPB)

[Raw transfer]




K11_A_2(3EWH)

[Raw transfer]




608_D_4(2P2I)

[Raw transfer]




42Q_A_2(3VHE)

[Raw transfer]




857_B_5(2QU6)

[Raw transfer]




42Q_A_2(3VHE)

[Raw transfer]




03X_A_2(3U6J)

[Raw transfer]




706_A_3(3EFL)
VGFR2_HUMAN
[Raw transfer]




900_B_4(3B8Q)

[Raw transfer]




0KF_A_2(3VO3)

[Raw transfer]




647_A_2(4HVS)
KIT_HUMAN
[Raw transfer]




608_C_3(2P2I)
VGFR2_HUMAN
[Raw transfer]




2RL_A_2(2RL5)

[Raw transfer]




00J_A_2(2XIR)

[Raw transfer]




64M_A_2(4HW7)

[Raw transfer]




900_A_3(3B8Q)
VGFR2_HUMAN
[Raw transfer]




C19_A_3(3CP9)
VGFR2_HUMAN
[Raw transfer]




BAX_A_2(4ASD)

[Raw transfer]




887_B_5(3B8R)

[Raw transfer]




AAX_B_2(1Y6B)

[Raw transfer]




887_A_4(3B8R)
VGFR2_HUMAN
[Raw transfer]




00J_A_2(2XIR)

[Raw transfer]




ACP_A_2(4K33)

[Raw transfer]




AXI_A_2(4AG8)

[Raw transfer]




994_B_2(2P2H)

[Raw transfer]




0JA_A_2(3VNT)

[Raw transfer]




RAJ_A_2(3BE2)

[Raw transfer]




C52_B_4(3CPC)

[Raw transfer]




C4F_A_3(3C4F)
FGFR1_HUMAN
[Raw transfer]




C4F_B_4(3C4F)

[Raw transfer]




GQL_B_5(3GQL)
FGFR1_HUMAN
[Raw transfer]




GQL_C_6(3GQL)

[Raw transfer]




A96_A_3(3DTW)
VGFR2_HUMAN
[Raw transfer]




ACP_B_8(4J98)
FGFR2_HUMAN
[Raw transfer]




AAZ_A_2(1Y6A)

[Raw transfer]




C52_A_3(3CPC)
VGFR2_HUMAN
[Raw transfer]




PD1_C_3(2FGI)

[Raw transfer]




0S9_B_18(4F65)

[Raw transfer]




PD1_D_4(2FGI)
FGFR1_HUMAN
[Raw transfer]




0S9_A_10(4F65)
FGFR1_HUMAN
[Raw transfer]




3RH_A_6(3RHX)
FGFR1_HUMAN
[Raw transfer]




ACP_A_7(2PZP)
FGFR2_HUMAN
[Raw transfer]




ACP_B_12(2PZP)

[Raw transfer]




GQL_A_4(3GQL)
FGFR1_HUMAN
[Raw transfer]




5CN_A_2(2I0Y)
?
[Raw transfer]




5CN_B_2(2I1M)

[Raw transfer]




ACP_D_16(4J99)
?
[Raw transfer]




07J_B_7(3TT0)

[Raw transfer]




3RH_B_3(3RHX)

[Raw transfer]




BPK_A_2(3VHK)

[Raw transfer]




07J_A_3(3TT0)
FGFR1_HUMAN
[Raw transfer]




ACP_A_6(4J99)
FGFR2_HUMAN
[Raw transfer]




0S8_B_7(4F64)

[Raw transfer]




5CN_B_2(2I1M)

[Raw transfer]




0S8_A_3(4F64)
FGFR1_HUMAN
[Raw transfer]




0S7_B_6(4F63)

[Raw transfer]




ACP_B_8(4J97)

[Raw transfer]




0S7_A_3(4F63)
FGFR1_HUMAN
[Raw transfer]




ACP_A_5(4J95)
FGFR2_HUMAN
[Raw transfer]




ADP_A_5(1PKG)
KIT_HUMAN
[Raw transfer]




ACP_B_7(4J96)
FGFR2_HUMAN
[Raw transfer]




6C3_A_3(2I0V)

[Raw transfer]




ACP_B_7(4J95)
?
[Raw transfer]




ACP_D_12(4J95)
?
[Raw transfer]




ACP_C_10(4J97)
?
[Raw transfer]




ACP_D_12(4J97)
?
[Raw transfer]




SU2_B_3(1AGW)

[Raw transfer]




SU1_B_3(1FGI)

[Raw transfer]




ACK_A_6(2IVS)
RET_HUMAN
[Raw transfer]




SU1_A_4(1FGI)
FGFR1_HUMAN
[Raw transfer]




SU2_A_4(1AGW)
FGFR1_HUMAN
[Raw transfer]




V4Z_A_4(4AOJ)
NTRK1_HUMAN
[Raw transfer]




VM1_A_3(3JS2)
FGFR1_HUMAN
[Raw transfer]




ACP_C_10(4J95)
?
[Raw transfer]




VM1_B_5(3JS2)

[Raw transfer]




STI_A_4(1T46)

[Raw transfer]




PP1_B_2(1QCF)
HCK_HUMAN
[Raw transfer]




ACP_A_5(4J97)
FGFR2_HUMAN
[Raw transfer]




ABG_D_12(2PVY)
?
[Raw transfer]




B49_A_3(3G0F)
?
[Raw transfer]




B49_A_2(3G0E)

[Raw transfer]




B49_B_5(3G0F)
?
[Raw transfer]




117 HHSearch 78.8994%-113 - C6 -2I1M 7.3
4 PsiBlast_PDB 77.7482%-122 - C6 -2I0Y 7.7 ?
3 PsiBlast_PDB 77.0882%-115 - C6 -2I0V 7.9
5 PsiBlast_PDB 76.6481%-110 - C6 -2I1M 7.3
2 PsiBlast_PDB 75.9687%-120 - C6 -4HW7 9.4
121 HHSearch 72.9169%-113 - C6 -1T46 11.1
8 PsiBlast_PDB 72.5360%-106 - C6 -4HVS 9.5 KIT_HUMAN
18 PsiBlast_PDB 71.9247%-120 - C6 -1Y6B 7.8
132 HHSearch 70.8049%-110 - C6 -3VHE 10.2
40 PsiBlast_CBE 70.2246%-124 - C6 -3B8R 8.9
17 PsiBlast_PDB 70.2247%-123 - C6 -1Y6A 6.0
20 PsiBlast_PDB 70.1248%-112 - C6 -3VHE 10.2
45 PsiBlast_CBE 70.0146%-127 - C6 -2QU6 9.7
66 PsiBlast_CBE 69.9444%-120 - C6 -4F64 2.3 FGFR1_HUMAN
41 PsiBlast_CBE 69.6946%-118 - C6 -3B8R 8.9 VGFR2_HUMAN
19 PsiBlast_PDB 69.6147%-107 - C6 -3VHK 6.3
88 PsiBlast_CBE 69.5643%-111 - C6 -3C4F 7.1 FGFR1_HUMAN
51 PsiBlast_CBE 69.5545%-113 - C6 -2P2I 9.3 VGFR2_HUMAN
106 PsiBlast_CBE 69.5443%-122 - C6 -2PVY 3.9 ?
96 PsiBlast_CBE 69.4443%-116 - C6 -4J97 4.7
35 PsiBlast_CBE 69.4446%-123 - C6 -3CPB 8.0
87 PsiBlast_CBE 69.4243%-112 - C6 -3C4F 6.9
43 PsiBlast_CBE 69.4246%-114 - C6 -3B8Q 9.6 VGFR2_HUMAN
97 PsiBlast_CBE 69.3943%-121 - C6 -4J97 4.1 FGFR2_HUMAN
37 PsiBlast_CBE 69.2746%-123 - C6 -3CP9 8.6
94 PsiBlast_CBE 69.1443%-117 - C6 -4J97 4.0 ?
86 PsiBlast_CBE 69.1143%-124 - C6 -4J99 5.0 FGFR2_HUMAN
74 PsiBlast_CBE 69.0444%-113 - C6 -1FGI 6.4 FGFR1_HUMAN
34 PsiBlast_CBE 69.0246%-119 - C6 -3CPC 9.0 VGFR2_HUMAN
104 PsiBlast_CBE 68.9443%-122 - C6 -4J95 4.3 ?
73 PsiBlast_CBE 68.9444%-122 - C6 -1FGI 6.5
105 PsiBlast_CBE 68.9043%-121 - C6 -4J95 4.6 FGFR2_HUMAN
36 PsiBlast_CBE 68.9046%-118 - C6 -3CPB 7.4 VGFR2_HUMAN
56 PsiBlast_CBE 68.8844%-114 - C6 -3RHX 6.0 FGFR1_HUMAN
52 PsiBlast_CBE 68.8744%-118 - C6 -4K33 7.8
48 PsiBlast_CBE 68.8445%-124 - C6 -3EFL 8.1
42 PsiBlast_CBE 68.7546%-118 - C6 -3B8Q 10.1
64 PsiBlast_CBE 68.7344%-118 - C6 -4F65 8.2 FGFR1_HUMAN
95 PsiBlast_CBE 68.7243%-117 - C6 -4J97 4.1 ?
135 HHSearch 68.6454%-113 - C6 -2XIR 9.3
92 PsiBlast_CBE 68.5943%-116 - C6 -3GQL 6.1 FGFR1_HUMAN
136 HHSearch 68.5346%-110 - C6 -2IVS 4.6 RET_HUMAN
85 PsiBlast_CBE 68.4743%-124 - C6 -4J99 5.8 ?
33 PsiBlast_CBE 68.4746%-122 - C6 -3CPC 9.3
38 PsiBlast_CBE 68.4546%-115 - C6 -3CP9 8.9 VGFR2_HUMAN
68 PsiBlast_CBE 68.3544%-116 - C6 -4F63 2.5 FGFR1_HUMAN
67 PsiBlast_CBE 68.2844%-121 - C6 -4F63 5.5
49 PsiBlast_CBE 68.2745%-110 - C6 -3EFL 8.3 VGFR2_HUMAN
46 PsiBlast_CBE 68.1846%-114 - C6 -2QU5 9.6
76 PsiBlast_CBE 68.0644%-117 - C6 -1AGW 5.7 FGFR1_HUMAN
103 PsiBlast_CBE 68.0543%-120 - C6 -4J95 4.5 ?
102 PsiBlast_CBE 68.0343%-119 - C6 -4J95 4.8 ?
22 PsiBlast_CBE 68.0246%-105 - C6 -3U6J 11.3
50 PsiBlast_CBE 67.9145%-124 - C6 -2P2I 8.8
32 PsiBlast_CBE 67.9146%-113 - C6 -3DTW 8.7 VGFR2_HUMAN
72 PsiBlast_CBE 67.9044%-119 - C6 -2FGI 7.5 FGFR1_HUMAN
91 PsiBlast_CBE 67.8943%-121 - C6 -3GQL 6.0
39 PsiBlast_CBE 67.8646%-111 - C6 -3BE2 11.2
83 PsiBlast_CBE 67.8243%-112 - C6 -4J96 4.5 FGFR2_HUMAN
93 PsiBlast_CBE 67.8043%-112 - C6 -3GQL 6.2 FGFR1_HUMAN
65 PsiBlast_CBE 67.6944%-120 - C6 -4F64 6.5
30 PsiBlast_CBE 67.6844%-108 - C6 -3VO3 8.8
80 PsiBlast_CBE 67.6544%-108 - C6 -3JS2 4.2 FGFR1_HUMAN
44 PsiBlast_CBE 67.5546%-110 - C6 -2RL5 9.7
71 PsiBlast_CBE 67.4444%-119 - C6 -2FGI 7.8
63 PsiBlast_CBE 67.4144%-118 - C6 -4F65 8.3
23 PsiBlast_CBE 67.4146%-109 - C6 -3EWH 10.7
89 PsiBlast_CBE 67.3943%-113 - C6 -2PZP 4.7
98 PsiBlast_CBE 67.2943%-111 - C6 -4J98 4.9 FGFR2_HUMAN
31 PsiBlast_CBE 67.2744%-109 - C6 -3VNT 9.0
81 PsiBlast_CBE 67.2344%-120 - C6 -3TT0 8.3
75 PsiBlast_CBE 67.2244%-121 - C6 -1AGW 5.5
55 PsiBlast_CBE 67.2144%-119 - C6 -3RHX 6.7
47 PsiBlast_CBE 67.1146%-114 - C6 -2P2H 6.9
82 PsiBlast_CBE 67.0144%-103 - C6 -3TT0 8.0 FGFR1_HUMAN
28 PsiBlast_CBE 66.8845%-110 - C6 -4AG8 8.7
29 PsiBlast_CBE 66.8445%-111 - C6 -2XIR 9.3
90 PsiBlast_CBE 66.7143%-116 - C6 -2PZP 4.5 FGFR2_HUMAN
79 PsiBlast_CBE 66.3144%-109 - C6 -3JS2 3.7
25 PsiBlast_CBE 66.1543%-106 - C6 -4ASD 9.5
119 HHSearch 65.6737%-109 - C6 -4AOJ 8.2 NTRK1_HUMAN
129 HHSearch 62.0243%-102 - C6 -1QCF 6.1 HCK_HUMAN
10 PsiBlast_PDB 58.3650% -70 - C6 -3G0E 4.6
11 PsiBlast_PDB 57.3250% -69 - C6 -3G0F 4.2 ?
21 PsiBlast_CBE 57.2750% -71 - C6 -3G0F 4.7 ?
16 PsiBlast_PDB 57.2450% -71 - C6 -1T46 6.5
14 PsiBlast_PDB 55.9150% -69 - C6 -1PKG 5.5 KIT_HUMAN