@TOME V2.3
(Nov 2016)

Ref. - - Doc.
Global output mode :
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Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Comparative Docking Tab: Displays ligands Score after transfer from template to model
Cell color: RMS between binding site of experimental template and receptor: [‹ 3Å | ‹ 10Å | › 10Å]
Result: [ Good | Correct | Acceptable | Bad | Empty = ligand not selected during the calculation step or result rejected ]

Query sequence : INSR_HUMAN: (2013-07-21 )
MATGGRRGAAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS

Atome Classification :

(73 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

EBI_A_2(3I81)

[Raw transfer]




LGV_A_2(3NW7)

[Raw transfer]




351_B_4(3ETA)

[Raw transfer]




351_A_3(3ETA)
INSR_HUMAN
[Raw transfer]




LGX_A_2(3NW5)

[Raw transfer]




ACP_A_3(1I44)

[Raw transfer]




01P_D_8(3QQU)

[Raw transfer]




LGW_A_2(3NW6)

[Raw transfer]




01P_B_6(3QQU)
IGF1R_HUMAN
[Raw transfer]




GS2_A_2(3EKK)

[Raw transfer]




CKJ_B_7(3TCP)

[Raw transfer]




0T8_A_2(4FEQ)

[Raw transfer]




ABG_A_7(2PWL)
FGFR2_HUMAN
[Raw transfer]




01P_A_5(3QQU)
IGF1R_HUMAN
[Raw transfer]




1BQ_A_2(4I4E)

[Raw transfer]




0S9_A_10(4F65)
FGFR1_HUMAN
[Raw transfer]




BMI_B_2(2OJ9)

[Raw transfer]




0S9_B_18(4F65)

[Raw transfer]




ABG_B_8(2PWL)
FGFR2_HUMAN
[Raw transfer]




ANP_B_9(1JQH)
IGF1R_HUMAN
[Raw transfer]




01P_C_7(3QQU)
IGF1R_HUMAN
[Raw transfer]




MUJ_A_2(4AT5)

[Raw transfer]




0F4_A_4(3V5Q)
NTRK3_HUMAN
[Raw transfer]




571_A_2(2XBA)

[Raw transfer]




V4Z_C_10(4AOJ)

[Raw transfer]




GS3_A_2(3EKN)

[Raw transfer]




C4F_B_4(3C4F)

[Raw transfer]




V4Z_B_7(4AOJ)
NTRK1_HUMAN
[Raw transfer]




ADP_A_3(3LCT)

[Raw transfer]




C4F_A_3(3C4F)
FGFR1_HUMAN
[Raw transfer]




PDR_A_5(3LVP)
IGF1R_HUMAN
[Raw transfer]




V4Z_A_4(4AOJ)
NTRK1_HUMAN
[Raw transfer]




GQL_A_4(3GQL)
FGFR1_HUMAN
[Raw transfer]




0JF_B_4(4DCE)

[Raw transfer]




0S7_B_6(4F63)

[Raw transfer]




GOL_A_2(3L9P)

[Raw transfer]




I3K_A_2(4FNY)

[Raw transfer]




CKJ_A_3(3TCP)
MERTK_HUMAN
[Raw transfer]




0JF_A_3(4DCE)
ALK_HUMAN
[Raw transfer]




GQL_B_5(3GQL)
FGFR1_HUMAN
[Raw transfer]




GQL_C_6(3GQL)

[Raw transfer]




NZF_A_2(4FNZ)

[Raw transfer]




GUI_A_2(2XB7)

[Raw transfer]




VGH_A_2(2YFX)

[Raw transfer]




SU1_B_3(1FGI)

[Raw transfer]




STU_A_2(3LCS)

[Raw transfer]




VGH_A_2(4ANS)

[Raw transfer]




0VF_A_2(4FYO)

[Raw transfer]




VGH_A_2(4ANQ)

[Raw transfer]




PP1_B_2(1QCF)
HCK_HUMAN
[Raw transfer]




3RH_A_3(3RI1)
?
[Raw transfer]




3RH_B_9(3RI1)
FGFR2_HUMAN
[Raw transfer]




LTI_A_2(4AT3)

[Raw transfer]




T6E_A_2(4AT4)

[Raw transfer]




0S8_B_7(4F64)

[Raw transfer]




0S8_A_3(4F64)
FGFR1_HUMAN
[Raw transfer]




ANP_A_6(2P0C)
MERTK_HUMAN
[Raw transfer]




3RH_B_3(3RHX)

[Raw transfer]




VGH_A_2(3ZBF)
?
[Raw transfer]




0UU_A_2(4FOC)

[Raw transfer]




0US_A_2(4FOB)

[Raw transfer]




OLP_A_8(3BPR)
MERTK_HUMAN
[Raw transfer]




ANP_B_7(2P0C)

[Raw transfer]




ADP_B_11(3BRB)

[Raw transfer]




0UV_A_2(4FOD)

[Raw transfer]




EMH_A_2(3AOX)

[Raw transfer]




VM1_A_3(3JS2)
FGFR1_HUMAN
[Raw transfer]




CCX_B_7(3LW0)
IGF1R_HUMAN
[Raw transfer]




CCX_A_5(3LW0)
IGF1R_HUMAN
[Raw transfer]




EDO_B_8(4F64)

[Raw transfer]




EDO_A_4(4F63)
FGFR1_HUMAN
[Raw transfer]




EDO_B_7(4F63)

[Raw transfer]




EDO_A_4(4F64)
FGFR1_HUMAN
[Raw transfer]




12 PsiBlast_PDB 61.3899% -97 - C2 -3EKK 7.5
17 PsiBlast_PDB 59.8980% -94 - C2 -3I81 8.6
11 PsiBlast_PDB 59.3799% -91 - C2 -1I44 5.6
30 PsiBlast_CBE 59.2979% -91 - C2 -3LW0 6.5 IGF1R_HUMAN
27 PsiBlast_CBE 58.8879% -89 - C2 -3LW0 -
13 PsiBlast_PDB 58.7699% -92 - C2 -3EKN 7.4
29 PsiBlast_CBE 58.7579% -90 - C2 -3LW0 7.3 IGF1R_HUMAN
24 PsiBlast_CBE 58.7380% -90 - C2 -3NW7 8.7
28 PsiBlast_CBE 58.5579% -89 - C2 -3LW0 - IGF1R_HUMAN
23 PsiBlast_CBE 58.55100% -87 - C2 -3ETA 12.2
9 PsiBlast_PDB 58.40100% -87 - C2 -3ETA 12.2 INSR_HUMAN
19 PsiBlast_PDB 57.7380% -90 - C2 -3NW5 7.4
20 PsiBlast_PDB 57.5180% -90 - C2 -3NW6 8.6
15 PsiBlast_PDB 57.4277% -96 - C2 -3LVP 5.9 IGF1R_HUMAN
34 PsiBlast_CBE 56.4880% -91 - C2 -3QQU 7.1 IGF1R_HUMAN
18 PsiBlast_PDB 56.3580% -88 - C2 -2OJ9 7.8
31 PsiBlast_CBE 56.1480% -88 - C2 -3QQU 6.8
33 PsiBlast_CBE 55.8280% -86 - C2 -3QQU 6.7 IGF1R_HUMAN
25 PsiBlast_CBE 55.6480% -85 - C2 -1JQH 4.3 IGF1R_HUMAN
32 PsiBlast_CBE 55.3880% -86 - C2 -3QQU 8.2 IGF1R_HUMAN
127 HHSearch 53.1143% -80 - C2 -4AOJ 5.7 NTRK1_HUMAN
61 PsiBlast_CBE 52.8342% -89 - C2 -3V5Q 10.3 NTRK3_HUMAN
128 HHSearch 52.4239% -82 * C2 *4I4E 5.9
49 PsiBlast_CBE 50.9645% -90 - C2 -2XBA 5.5
50 PsiBlast_CBE 50.8445% -84 - C2 -2XB7 7.2
46 PsiBlast_CBE 50.7244% -80 - C2 -4DCE 8.9 ALK_HUMAN
45 PsiBlast_CBE 50.6644% -80 - C2 -4DCE 9.6
56 PsiBlast_CBE 50.5644% -85 - C2 -4AT4 8.6
57 PsiBlast_CBE 50.4844% -84 - C2 -4AT3 5.5
66 PsiBlast_CBE 50.2840% -91 - C2 -1FGI 6.3
55 PsiBlast_CBE 50.2544% -83 - C2 -4AT5 7.5
51 PsiBlast_CBE 49.8744% -77 - C2 -4FNZ 9.6
59 PsiBlast_CBE 49.6042% -83 - C2 -4AOJ 6.4 NTRK1_HUMAN
52 PsiBlast_CBE 49.5143% -84 - C2 -4FNY 9.6
58 PsiBlast_CBE 49.3742% -82 - C2 -4AOJ 6.8
82 PsiBlast_CBE 48.9439% -82 - C2 -3C4F 6.7
73 PsiBlast_CBE 48.6639% -88 - C2 -4F65 6.8 FGFR1_HUMAN
72 PsiBlast_CBE 48.6539% -87 - C2 -4F65 7.4
96 PsiBlast_CBE 48.3540% -93 - C2 -4FEQ 6.1
62 PsiBlast_CBE 48.3439% -85 - C2 -3RHX 6.9
36 PsiBlast_CBE 48.1743% -81 - C2 -4ANS 6.8
85 PsiBlast_CBE 48.1139% -79 - C2 -3GQL 6.7 FGFR1_HUMAN
75 PsiBlast_CBE 47.8239% -87 - C2 -4F64 5.3 FGFR1_HUMAN
37 PsiBlast_CBE 47.7444% -80 - C2 -2YFX 6.8
87 PsiBlast_CBE 47.5941% -88 - C2 -3TCP 7.1
48 PsiBlast_CBE 47.5644% -78 - C2 -4FOB 6.8
92 PsiBlast_CBE 47.5041% -87 - C2 -3BPR 5.4 MERTK_HUMAN
83 PsiBlast_CBE 47.4539% -84 - C2 -3C4F 6.9 FGFR1_HUMAN
40 PsiBlast_CBE 47.4544% -81 - C2 -3AOX 8.5
47 PsiBlast_CBE 47.3844% -79 - C2 -4FOC 7.3
38 PsiBlast_CBE 47.3543% -79 - C2 -4ANQ 6.8
35 PsiBlast_CBE 47.2249% -80 - C2 -3ZBF 6.5 ?
77 PsiBlast_CBE 47.1439% -88 - C2 -4F63 1.7 FGFR1_HUMAN
94 PsiBlast_CBE 46.9841% -90 - C2 -2P0C 4.2 MERTK_HUMAN
44 PsiBlast_CBE 46.9044% -79 - C2 -4FOD 9.4
105 PsiBlast_CBE 46.8939% -83 - C2 -3RI1 6.7 ?
74 PsiBlast_CBE 46.8439% -85 - C2 -4F64 5.9
88 PsiBlast_CBE 46.8141% -88 - C2 -3TCP 6.7 MERTK_HUMAN
81 PsiBlast_CBE 46.7440% -76 - C2 -3JS2 3.9 FGFR1_HUMAN
84 PsiBlast_CBE 46.6939% -85 - C2 -3GQL 5.9
130 HHSearch 46.5334% -82 - C2 -4FYO 5.7
93 PsiBlast_CBE 46.2741% -88 - C2 -2P0C 3.5
89 PsiBlast_CBE 46.1941% -85 - C2 -3BRB 4.3
76 PsiBlast_CBE 46.1639% -84 - C2 -4F63 5.3
134 HHSearch 46.0635% -78 - C2 -1QCF 5.4 HCK_HUMAN
86 PsiBlast_CBE 45.8539% -75 - C2 -3GQL 6.2 FGFR1_HUMAN
43 PsiBlast_CBE 45.1444% -75 - C2 -3LCS 8.2
41 PsiBlast_CBE 45.0644% -75 - C2 -3L9P 2.6
99 PsiBlast_CBE 44.4839% -80 - C2 -2IVS - RET_HUMAN
104 PsiBlast_CBE 44.4039% -81 - C2 -3RI1 6.8 FGFR2_HUMAN
98 PsiBlast_CBE 44.3039% -78 - C2 -2PWL 4.6 FGFR2_HUMAN
97 PsiBlast_CBE 43.9939% -78 - C2 -2PWL 4.9 FGFR2_HUMAN
42 PsiBlast_CBE 43.9844% -73 - C2 -3LCT 4.3


Add PDB User Result:

(38 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

EBI_A_2(3I81)

[Raw transfer]




LGV_A_2(3NW7)

[Raw transfer]




351_B_4(3ETA)

[Raw transfer]




351_A_3(3ETA)
INSR_HUMAN
[Raw transfer]




LGX_A_2(3NW5)

[Raw transfer]




ACP_A_3(1I44)

[Raw transfer]




01P_D_8(3QQU)

[Raw transfer]




LGW_A_2(3NW6)

[Raw transfer]




01P_B_6(3QQU)
IGF1R_HUMAN
[Raw transfer]




GS2_A_2(3EKK)

[Raw transfer]




CKJ_B_7(3TCP)

[Raw transfer]




0T8_A_2(4FEQ)

[Raw transfer]




ABG_A_7(2PWL)
FGFR2_HUMAN
[Raw transfer]




01P_A_5(3QQU)
IGF1R_HUMAN
[Raw transfer]




1BQ_A_2(4I4E)

[Raw transfer]




0S9_A_10(4F65)
FGFR1_HUMAN
[Raw transfer]




BMI_B_2(2OJ9)

[Raw transfer]




0S9_B_18(4F65)

[Raw transfer]




ABG_B_8(2PWL)
FGFR2_HUMAN
[Raw transfer]




ANP_B_9(1JQH)
IGF1R_HUMAN
[Raw transfer]




01P_C_7(3QQU)
IGF1R_HUMAN
[Raw transfer]




MUJ_A_2(4AT5)

[Raw transfer]




0F4_A_4(3V5Q)
NTRK3_HUMAN
[Raw transfer]




571_A_2(2XBA)

[Raw transfer]




V4Z_C_10(4AOJ)

[Raw transfer]




GS3_A_2(3EKN)

[Raw transfer]




C4F_B_4(3C4F)

[Raw transfer]




V4Z_B_7(4AOJ)
NTRK1_HUMAN
[Raw transfer]




ADP_A_3(3LCT)

[Raw transfer]




C4F_A_3(3C4F)
FGFR1_HUMAN
[Raw transfer]




PDR_A_5(3LVP)
IGF1R_HUMAN
[Raw transfer]




V4Z_A_4(4AOJ)
NTRK1_HUMAN
[Raw transfer]




GQL_A_4(3GQL)
FGFR1_HUMAN
[Raw transfer]




0JF_B_4(4DCE)

[Raw transfer]




0S7_B_6(4F63)

[Raw transfer]




GOL_A_2(3L9P)

[Raw transfer]




I3K_A_2(4FNY)

[Raw transfer]




CKJ_A_3(3TCP)
MERTK_HUMAN
[Raw transfer]




0JF_A_3(4DCE)
ALK_HUMAN
[Raw transfer]




GQL_B_5(3GQL)
FGFR1_HUMAN
[Raw transfer]




GQL_C_6(3GQL)

[Raw transfer]




NZF_A_2(4FNZ)

[Raw transfer]




GUI_A_2(2XB7)

[Raw transfer]




VGH_A_2(2YFX)

[Raw transfer]




SU1_B_3(1FGI)

[Raw transfer]




STU_A_2(3LCS)

[Raw transfer]




VGH_A_2(4ANS)

[Raw transfer]




0VF_A_2(4FYO)

[Raw transfer]




VGH_A_2(4ANQ)

[Raw transfer]




PP1_B_2(1QCF)
HCK_HUMAN
[Raw transfer]




3RH_A_3(3RI1)
?
[Raw transfer]




3RH_B_9(3RI1)
FGFR2_HUMAN
[Raw transfer]




LTI_A_2(4AT3)

[Raw transfer]




T6E_A_2(4AT4)

[Raw transfer]




0S8_B_7(4F64)

[Raw transfer]




0S8_A_3(4F64)
FGFR1_HUMAN
[Raw transfer]




ANP_A_6(2P0C)
MERTK_HUMAN
[Raw transfer]




3RH_B_3(3RHX)

[Raw transfer]




VGH_A_2(3ZBF)
?
[Raw transfer]




0UU_A_2(4FOC)

[Raw transfer]




0US_A_2(4FOB)

[Raw transfer]




OLP_A_8(3BPR)
MERTK_HUMAN
[Raw transfer]




ANP_B_7(2P0C)

[Raw transfer]




ADP_B_11(3BRB)

[Raw transfer]




0UV_A_2(4FOD)

[Raw transfer]




EMH_A_2(3AOX)

[Raw transfer]




VM1_A_3(3JS2)
FGFR1_HUMAN
[Raw transfer]




CCX_B_7(3LW0)
IGF1R_HUMAN
[Raw transfer]




CCX_A_5(3LW0)
IGF1R_HUMAN
[Raw transfer]




EDO_B_8(4F64)

[Raw transfer]




EDO_A_4(4F63)
FGFR1_HUMAN
[Raw transfer]




EDO_B_7(4F63)

[Raw transfer]




EDO_A_4(4F64)
FGFR1_HUMAN
[Raw transfer]




139 -100% -90 - C2 -U139 - -
140 -100% -86 - C2 -U140 - -
141 -100% -87 - C2 -U141 - -
142 -100% -86 - C2 -U142 - -
143 -100% -92 - C2 -U143 - -
144 -100%-101 - C2 -U144 - -
145 -100% -91 - C2 -U145 - -
146 -100% -92 - C2 -U146 - -
147 -100% -92 - C2 -U147 - -
148 -100% -87 - C2 -U148 - -
149 -100% -92 - C2 -U149 - -
150 -100% -90 - C2 -U150 - -
151 -100% -92 - C2 -U151 - -
152 -99% -88 - C2 -U152 - -
153 -100% -92 - C2 -U153 - -
154 -99% -88 - C2 -U154 - -
155 -100% -92 - C2 -U155 - -
156 -100% -92 - C2 -U156 - -
157 -100% -92 - C2 -U157 - -
158 -100% -92 - C2 -U158 - -
159 -100% -92 - C2 -U159 - -
160 -100%-101 - C2 -U160 - -
161 -100% -92 - C2 -U161 - -
162 -100% -97 - C2 -U162 - -
163 -100% -92 - C2 -U163 - -
164 -100% -92 - C2 -U164 - -
165 -99% -96 - C2 -U165 - -
166 -100% -92 - C2 -U166 - -
167 -100% -92 - C2 -U167 - -
168 -100% -97 - C2 -U168 - -
169 -99% -98 - C2 -U169 - -
170 -100% -97 - C2 -U170 - -
171 -100% -92 - C2 -U171 - -
172 -100% -92 - C2 -U172 - -
173 -100% -95 - C2 -U173 - -
174 -100% -92 - C2 -U174 - -
175 -100% -91 - C2 -U175 - -
176 -99% -96 - C2 -U176 - -