@TOME V2.3
(Nov 2016)

Ref. - - Doc.
Global output mode :
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Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Comparative Docking Tab: Displays ligands Score after transfer from template to model
Cell color: RMS between binding site of experimental template and receptor: [‹ 3Å | ‹ 10Å | › 10Å]
Result: [ Good | Correct | Acceptable | Bad | Empty = ligand not selected during the calculation step or result rejected ]

Query sequence : TYK2_HUMAN: (2015-06-18 )
MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC

Atome Classification :

(24 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

0MX_A_2(4E1Z)

[Raw transfer]



0MY_A_2(4E20)

[Raw transfer]



ADP_A_2(4GVJ)

[Raw transfer]



MI1_A_2(3LXN)

[Raw transfer]



0X5_A_2(4GIH)

[Raw transfer]



0XP_A_2(4GJ3)

[Raw transfer]



0XH_A_2(4GJ2)

[Raw transfer]



0X6_A_2(4GII)

[Raw transfer]



0NH_B_6(4E4M)
JAK2_HUMAN
[Raw transfer]



C5I_B_8(4I5C)

[Raw transfer]



0X2_A_7(4GFO)

[Raw transfer]



1Q3_A_2(4K6Z)

[Raw transfer]



F9J_B_6(3ZMM)

[Raw transfer]



IZA_A_2(3NZ0)

[Raw transfer]



TZ1_A_2(3NYX)

[Raw transfer]



0NH_D_7(4E4M)
JAK2_HUMAN
[Raw transfer]



1J5_B_4(4IVB)

[Raw transfer]



IZA_A_2(3LXP)

[Raw transfer]



1J6_B_4(4IVC)

[Raw transfer]



1K3_A_2(4JIA)

[Raw transfer]



046_A_2(3UGC)

[Raw transfer]



1BQ_A_2(4I4E)

[Raw transfer]



JAK_A_3(4F08)
JAK2_HUMAN
[Raw transfer]



15T_A_3(4IVD)
JAK1_HUMAN
[Raw transfer]



3KC_A_2(3KCK)

[Raw transfer]



STU_B_2(1BYG)
CSK_HUMAN
[Raw transfer]



1Q4_A_3(4K77)
JAK1_HUMAN
[Raw transfer]



V4Z_A_4(4AOJ)
NTRK1_HUMAN
[Raw transfer]
6 PsiBlast_PDB 62.2798%-118 - C2 -4GFO 4.8
4 PsiBlast_PDB 61.6899%-112 - C2 -3NZ0 8.0
15 PsiBlast_PDB 60.9991%-109 - C2 -4E1Z 9.3
12 PsiBlast_PDB 60.3897%-104 - C2 -4GJ2 6.5
7 PsiBlast_PDB 59.8497%-108 - C2 -3LXN 6.3
13 PsiBlast_PDB 59.6697%-104 - C2 -4GJ3 6.8
14 PsiBlast_PDB 59.4697%-105 - C2 -4GIH 6.3
16 PsiBlast_PDB 58.9291%-114 - C2 -4E20 7.5
11 PsiBlast_PDB 58.5797%-104 - C2 -4GII 6.9
5 PsiBlast_PDB 58.0898%-112 - C2 -3NYX 9.0
10 PsiBlast_PDB 57.9397%-104 - C2 -4GVJ 5.8
65 PsiBlast_CBE 54.2350%-105 - C2 -4E4M 5.5 JAK2_HUMAN
62 PsiBlast_CBE 53.6950%-100 - C2 -4F08 4.9 JAK2_HUMAN
76 PsiBlast_CBE 53.6650%-103 - C2 -4JIA 8.0
23 PsiBlast_CBE 50.9757%-103 - C2 -4K6Z 6.3
28 PsiBlast_CBE 50.6557% -99 - C2 -4IVB 6.5
25 PsiBlast_CBE 50.4757%-100 - C2 -4IVD 6.8 JAK1_HUMAN
22 PsiBlast_CBE 50.3757%-100 - C2 -4K77 5.1 JAK1_HUMAN
30 PsiBlast_CBE 50.1957%-100 - C2 -4I5C 6.6
26 PsiBlast_CBE 49.7857% -98 - C2 -4IVC 6.9
121 HHSearch 48.1851% -94 - C2 -3UGC 12.2
118 HHSearch 39.6837% -97 - C2 -4I4E 6.1
114 HHSearch 39.2738% -95 - C2 -4AOJ 7.8 NTRK1_HUMAN
102 Fugue 37.2838% -82 - C2 -1BYG 7.5 CSK_HUMAN