@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Comparative Docking Tab: Displays ligands Score after transfer from template to model
Cell color: RMS between binding site of experimental template and receptor: [‹ 3Å | ‹ 10Å | › 10Å]
Result: [ Good | Correct | Acceptable | Bad | Empty = ligand not selected during the calculation step or result rejected ]

Query sequence : ROS1_HUMAN: (2015-10-18 )
MKNIYCLIPKLVNFATLGCLWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHNLSEPCIQGCHFWNSVDQKNCALKCRESCEVGCSSAEGAYEEEVLENADLPTAPFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSRPSYVVKPLHPFTEYIFRVVWIFTAQLQLYSPPSPSYRTHPHGVPETAPLIRNIESSSPDTVEVSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYRFSIAAVNEVGEGPEAESSITTSSSAVQQEEQWLFLSRKTSLRKRSLKHLVDEAHCLRLDAIYHNITGISVDVHQQIVYFSEGTLIWAKKAANMSDVSDLRIFYRGSGLISSISIDWLYQRMYFIMDELVCVCDLENCSNIEEITPPSISAPQKIVADSYNGYVFYLLRDGIYRADLPVPSGRCAEAVRIVESCTLKDFAIKPQAKRIIYFNDTAQVFMSTFLDGSASHLILPRIPFADVKSFACENNDFLVTDGKVIFQQDALSFNEFIVGCDLSHIEEFGFGNLVIFGSSSQLHPLPGRPQELSVLFGSHQALVQWKPPALAIGANVILISDIIELFELGPSAWQNWTYEVKVSTQDPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVGTTLVPASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTKGDVFVWLLNGTDISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIVTHVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQTQPWFSGKKVIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQSTGDTTITEFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQKTSVSVLEPARFNQFTIIQTSLKPLPGNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSKFLASEQHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPETVPSAPENPRIFILPSGKCCNKNEVVVEFRWNKPKHENGVLTKFEIFYNISNQSITNKTCEDWIAVNVTPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPYADVVKSTTSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAVCYTADNEMGYYAEGDSLFLLHLHNRSSSELFQDSLVFDITVITIDWISRHLYFALKESQNGMQVFDVDLEHKVKYPREVKIHNRNSTIISFSVYPLLSRLYWTEVSNFGYQMFYYSIISHTLHRILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKAQEIWAMDLEGCQCWRVITVPAMLAGKTLVSLTVDGDLIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRHILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTWYGITSPTPTYLVYYAEVNDRKNSSDLKYRILEFQDSIALIEDLQPFSTYMIQIAVKNYYSDPLEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISHLALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLKVLACHSEEMWCTESHPVTVEMFNTPEKPYSLVPENTSLQFNWKAPLNVNLIRFWVELQKWKYNEFYHVKTSCSQGPAYVCNITNLQPYTSYNVRVVVVYKTGENSTSLPESFKTKAGVPNKPGIPKLLEGSKNSIQWEKAEDNGCRITYYILEIRKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVICLNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSGYGDGSD

Atome Classification :

(68 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

ACP_A_2(4K33)

[Raw transfer]



ACP_A_6(4J99)
FGFR2_HUMAN
[Raw transfer]



351_A_3(3ETA)
INSR_HUMAN
[Raw transfer]



351_B_4(3ETA)

[Raw transfer]



LGW_A_2(3NW6)

[Raw transfer]



ACP_B_12(2PY3)

[Raw transfer]



EBI_A_2(3I81)

[Raw transfer]



LGX_A_2(3NW5)

[Raw transfer]



ACP_B_9(4J99)

[Raw transfer]



ACP_B_12(2PZP)

[Raw transfer]



ACP_C_12(4J99)
?
[Raw transfer]



LGV_A_2(3NW7)

[Raw transfer]



ACP_A_7(2PZP)
FGFR2_HUMAN
[Raw transfer]



IR1_A_3(4IBM)
?
[Raw transfer]



ABG_A_7(2PWL)
FGFR2_HUMAN
[Raw transfer]



IR1_B_4(4IBM)
?
[Raw transfer]



ACP_A_7(2PZ5)
FGFR2_HUMAN
[Raw transfer]



ACP_A_5(4J95)
FGFR2_HUMAN
[Raw transfer]



ACP_A_3(1I44)

[Raw transfer]



ACP_D_16(4J99)
?
[Raw transfer]



ACP_B_8(4J98)
FGFR2_HUMAN
[Raw transfer]



ABG_B_8(2PWL)
FGFR2_HUMAN
[Raw transfer]



ACP_A_7(2PY3)
FGFR2_HUMAN
[Raw transfer]



01P_D_8(3QQU)

[Raw transfer]



ACP_B_7(4J95)
?
[Raw transfer]



FMT_A_3(2IVS)
RET_HUMAN
[Raw transfer]



01P_A_5(3QQU)
IGF1R_HUMAN
[Raw transfer]



ACP_D_12(4J95)
?
[Raw transfer]



01P_B_6(3QQU)
IGF1R_HUMAN
[Raw transfer]



GOL_A_8(4YNE)

[Raw transfer]



ACP_B_12(2PZ5)

[Raw transfer]



ACP_C_10(4J97)
?
[Raw transfer]



FMT_A_4(2IVS)
RET_HUMAN
[Raw transfer]



31Y_A_2(4PMT)

[Raw transfer]



ACP_B_7(4J96)
FGFR2_HUMAN
[Raw transfer]



ACP_B_8(4J97)

[Raw transfer]



01P_C_7(3QQU)
IGF1R_HUMAN
[Raw transfer]



STI_A_2(4CSV)
?
[Raw transfer]



STU_A_13(3BKB)

[Raw transfer]



ACK_A_6(2IVS)
RET_HUMAN
[Raw transfer]



ACP_A_2(4UEU)
?
[Raw transfer]



3RH_A_3(3RI1)
?
[Raw transfer]



3RH_B_9(3RI1)
FGFR2_HUMAN
[Raw transfer]



GS2_A_2(3EKK)

[Raw transfer]



4EK_A_2(4YNE)

[Raw transfer]



ACP_D_12(4J97)
?
[Raw transfer]



ACP_C_10(4J95)
?
[Raw transfer]



STU_A_3(3CBL)

[Raw transfer]



ACP_A_5(4J97)
FGFR2_HUMAN
[Raw transfer]



31W_A_2(4PMP)

[Raw transfer]



ANP_B_9(1JQH)
IGF1R_HUMAN
[Raw transfer]



GS3_A_2(3EKN)

[Raw transfer]



FMT_A_5(2IVS)
RET_HUMAN
[Raw transfer]



DYK_A_3(4D2R)

[Raw transfer]



PDR_A_5(3LVP)
IGF1R_HUMAN
[Raw transfer]



4F6_A_2(4YPS)

[Raw transfer]



BMI_B_2(2OJ9)

[Raw transfer]



M33_B_8(3B2T)

[Raw transfer]



AA2_A_4(1OEC)

[Raw transfer]



ABG_D_12(2PVY)
?
[Raw transfer]



ABG_A_7(2Q0B)
FGFR2_HUMAN
[Raw transfer]



ABG_A_7(2PZR)
FGFR2_HUMAN
[Raw transfer]



ABG_B_8(2Q0B)

[Raw transfer]



ABG_B_8(2PZR)

[Raw transfer]



CCX_A_5(3LW0)
IGF1R_HUMAN
[Raw transfer]



CCX_C_10(3LW0)
IGF1R_HUMAN
[Raw transfer]



CCX_D_13(3LW0)

[Raw transfer]



CCX_B_7(3LW0)
IGF1R_HUMAN
[Raw transfer]



EDO_A_7(3BKB)

[Raw transfer]



EDO_A_11(3BKB)

[Raw transfer]
62 PsiBlast_CBE 81.6242% -52 - C2 -2IVS 5.3 RET_HUMAN
80 PsiBlast_CBE 79.0742% -60 - C2 -4J97 4.2 FGFR2_HUMAN
40 PsiBlast_CBE 78.7050% -46 - C2 -3LW0 6.5 IGF1R_HUMAN
56 PsiBlast_CBE 78.5249% -38 - C2 -3ETA 11.4 INSR_HUMAN
39 PsiBlast_CBE 78.1350% -45 - C2 -3LW0 7.0 IGF1R_HUMAN
19 PsiBlast_PDB 77.8548% -50 - C2 -4TT7 -
54 PsiBlast_CBE 77.6049% -43 - C2 -3QQU 5.0 IGF1R_HUMAN
67 PsiBlast_CBE 77.5342% -46 - C2 -3CBL 8.6
37 PsiBlast_CBE 77.3050% -43 - C2 -3LW0 7.1
38 PsiBlast_CBE 77.2050% -44 - C2 -3LW0 6.7 IGF1R_HUMAN
50 PsiBlast_CBE 76.9449% -38 - C2 -4IBM 6.4 ?
79 PsiBlast_CBE 76.7942% -55 - C2 -4J97 4.5
55 PsiBlast_CBE 76.7349% -40 - C2 -3ETA 11.5
103 PsiBlast_CBE 76.4840% -48 - C2 -4PMP 8.3
3 PsiBlast_PDB 76.3548% -49 - C2 -3L9P -
78 PsiBlast_CBE 76.2842% -55 - C2 -4J97 4.2 ?
61 PsiBlast_CBE 76.1649% -40 - C2 -1I44 5.0
4 PsiBlast_PDB 76.1348% -51 - C2 -4MKC -
105 PsiBlast_CBE 76.0842% -53 - C2 -2PY3 5.2 FGFR2_HUMAN
60 PsiBlast_CBE 76.0649% -45 - C2 -3EKK 6.8
106 PsiBlast_CBE 75.8341% -52 - C2 -4K33 7.3
92 PsiBlast_CBE 75.8242% -57 - C2 -4J99 5.7 ?
91 PsiBlast_CBE 75.5042% -54 - C2 -3RI1 5.9 ?
17 PsiBlast_PDB 75.4948% -50 - C2 -3LCS -
49 PsiBlast_CBE 75.4449% -37 - C2 -4IBM 5.5 ?
81 PsiBlast_CBE 75.4242% -54 - C2 -4J98 5.1 FGFR2_HUMAN
53 PsiBlast_CBE 75.1349% -39 - C2 -3QQU 5.8 IGF1R_HUMAN
44 PsiBlast_CBE 75.0249% -44 - C2 -3NW6 5.8
87 PsiBlast_CBE 74.9042% -56 - C2 -4J95 4.4 ?
85 PsiBlast_CBE 74.8442% -57 - C2 -4J95 5.2 ?
89 PsiBlast_CBE 74.8342% -60 - C2 -2PVY 3.7 ?
73 PsiBlast_CBE 74.8342% -53 - C2 -2PZR 2.9
94 PsiBlast_CBE 74.7742% -57 - C2 -4J99 4.5
90 PsiBlast_CBE 74.7242% -52 - C2 -3RI1 5.6 FGFR2_HUMAN
88 PsiBlast_CBE 74.6542% -56 - C2 -4J95 4.5 FGFR2_HUMAN
98 PsiBlast_CBE 74.5542% -52 - C2 -4J96 4.4 FGFR2_HUMAN
83 PsiBlast_CBE 74.3442% -45 - C2 -1OEC 6.9
71 PsiBlast_CBE 74.3443% -49 * C2 *2PWL 4.8 FGFR2_HUMAN
72 PsiBlast_CBE 74.1343% -47 - C2 -2PWL 5.2 FGFR2_HUMAN
104 PsiBlast_CBE 74.1042% -50 - C2 -2PY3 5.6
86 PsiBlast_CBE 74.0942% -55 - C2 -4J95 4.2 ?
65 PsiBlast_CBE 74.0843% -54 - C2 -2PZP 4.9
70 PsiBlast_CBE 74.0543% -53 - C2 -2PZ5 4.9 FGFR2_HUMAN
41 PsiBlast_CBE 74.0049% -46 - C2 -3I81 7.5
66 PsiBlast_CBE 73.9943% -53 - C2 -2PZP 4.6 FGFR2_HUMAN
46 PsiBlast_CBE 73.9549% -40 - C2 -2OJ9 7.5
68 PsiBlast_CBE 73.8442% -40 - C2 -3BKB 8.7
107 PsiBlast_CBE 73.8042% -54 - C2 -3B2T 4.1
59 PsiBlast_CBE 73.7149% -42 - C2 -3EKN 5.7
58 PsiBlast_CBE 73.6249% -45 - C2 -4D2R 7.1
101 PsiBlast_CBE 73.4540% -52 - C2 -4YNE 8.4
95 PsiBlast_CBE 73.4242% -55 - C2 -4J99 4.9 FGFR2_HUMAN
74 PsiBlast_CBE 73.3542% -56 - C2 -2PZR 3.0 FGFR2_HUMAN
69 PsiBlast_CBE 73.3443% -54 - C2 -2PZ5 4.9
42 PsiBlast_CBE 73.3349% -40 - C2 -1JQH 4.0 IGF1R_HUMAN
97 PsiBlast_CBE 73.1842% -55 - C2 -2Q0B 4.3 FGFR2_HUMAN
45 PsiBlast_CBE 73.1149% -44 - C2 -3NW5 6.9
100 PsiBlast_CBE 73.0540% -46 - C2 -4YPS 4.6
43 PsiBlast_CBE 72.9449% -46 - C2 -3NW7 7.8
93 PsiBlast_CBE 72.8142% -57 - C2 -4J99 5.5 ?
77 PsiBlast_CBE 72.8142% -57 - C2 -4J97 4.4 ?
48 PsiBlast_CBE 72.4349% -51 - C2 -3LVP 5.8 IGF1R_HUMAN
96 PsiBlast_CBE 72.3242% -52 - C2 -2Q0B 3.9
51 PsiBlast_CBE 72.3049% -44 - C2 -3QQU 5.1
102 PsiBlast_CBE 71.6440% -50 - C2 -4PMT 6.8
52 PsiBlast_CBE 71.4149% -39 - C2 -3QQU 6.7 IGF1R_HUMAN
64 PsiBlast_CBE 71.0943% -47 - C2 -4CSV 9.0 ?
63 PsiBlast_CBE 70.5443% -45 - C2 -4UEU 5.0 ?