@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Comparative Docking Tab: Displays ligands Score after transfer from template to model
Cell color: RMS between binding site of experimental template and receptor: [‹ 3Å | ‹ 10Å | › 10Å]
Result: [ Good | Correct | Acceptable | Bad | Empty = ligand not selected during the calculation step or result rejected ]

Query sequence : WNK2_HUMAN: (2015-10-22 )
MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQGPCRGLTLPCLPWRRAACGAVFLSLFSAESAQSKQPPDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDGALGTARRNQVWFGLRVPPTACCGHSTQPRGGQRVGSKTASFAASDPVRS

Atome Classification :

(63 SA) Binding Score for complex ligand / Scwrl (Unconserved SChains Recalculated) model (Only selected ligand are displayed)
(Atome) (Ident) (Tito) (Num) (pKd) (Uniprot)

4Z5_A_3(5C9C)
?
[Raw transfer]



T1Q_A_3(4E4X)
BRAF_HUMAN
[Raw transfer]



RI9_B_4(4EHG)

[Raw transfer]



B0R_A_3(3TV6)
BRAF_HUMAN
[Raw transfer]



GOL_A_3(3FPQ)
WNK1_RAT
[Raw transfer]



1SU_A_3(4KSP)
BRAF_HUMAN
[Raw transfer]



T1Q_B_4(4E4X)

[Raw transfer]



BR2_A_3(3SKC)
BRAF_HUMAN
[Raw transfer]



55J_B_4(5CT7)
?
[Raw transfer]



0T2_A_3(4FC0)
BRAF_HUMAN
[Raw transfer]



0WP_B_4(4G9C)

[Raw transfer]



RI9_A_3(4EHG)
BRAF_HUMAN
[Raw transfer]



BR2_B_4(3SKC)

[Raw transfer]



55J_A_3(5CT7)
?
[Raw transfer]



B96_D_8(4JVG)

[Raw transfer]



324_B_4(4WO5)

[Raw transfer]



B96_A_6(4JVG)
BRAF_HUMAN
[Raw transfer]



TV4_B_4(3TV4)

[Raw transfer]



BAX_B_4(1UWH)

[Raw transfer]



DFS_B_4(4MBJ)

[Raw transfer]



032_A_3(3OG7)
BRAF_HUMAN
[Raw transfer]



324_A_3(3C4C)
BRAF_HUMAN
[Raw transfer]



BAX_A_3(1UWH)
BRAF_HUMAN
[Raw transfer]



B96_B_5(4JVG)
BRAF_HUMAN
[Raw transfer]



B96_C_7(4JVG)
BRAF_HUMAN
[Raw transfer]



B0R_B_4(3TV6)

[Raw transfer]



0WP_A_3(4G9C)
BRAF_HUMAN
[Raw transfer]



B1E_A_3(4G9R)
BRAF_HUMAN
[Raw transfer]



B1E_B_4(4G9R)

[Raw transfer]



RI8_B_4(4EHE)

[Raw transfer]



2VX_A_3(4PP7)
BRAF_HUMAN
[Raw transfer]



L1E_A_4(3IDP)
BRAF_HUMAN
[Raw transfer]



L1E_B_3(3IDP)

[Raw transfer]



FNI_B_4(3PPK)

[Raw transfer]



325_A_3(4FK3)
BRAF_HUMAN
[Raw transfer]



2VX_B_4(4PP7)

[Raw transfer]



RI8_A_3(4EHE)
BRAF_HUMAN
[Raw transfer]



SM7_B_4(3PSD)

[Raw transfer]



BAX_B_4(1UWJ)

[Raw transfer]



324_A_3(4WO5)
BRAF_HUMAN
[Raw transfer]



SM7_A_3(3PSD)
BRAF_HUMAN
[Raw transfer]



BAX_A_3(1UWJ)
BRAF_HUMAN
[Raw transfer]



FP4_B_4(3PRI)

[Raw transfer]



FNI_A_3(3PPK)
BRAF_HUMAN
[Raw transfer]



SM6_A_3(3PSB)
BRAF_HUMAN
[Raw transfer]



FP4_A_3(3PRI)
BRAF_HUMAN
[Raw transfer]



324_B_4(3C4C)

[Raw transfer]



FOI_B_4(3PPJ)

[Raw transfer]



SM6_B_4(3PSB)

[Raw transfer]



SM5_A_3(3D4Q)
BRAF_HUMAN
[Raw transfer]



SM5_B_4(3D4Q)

[Raw transfer]



29L_B_4(4MNF)

[Raw transfer]



29L_A_3(4MNF)
BRAF_HUMAN
[Raw transfer]



831_A_3(3II5)
BRAF_HUMAN
[Raw transfer]



DFS_A_3(4MBJ)
BRAF_HUMAN
[Raw transfer]



4J7_A_2(4YUR)
PLK4_HUMAN
[Raw transfer]



FOI_A_3(3PPJ)
BRAF_HUMAN
[Raw transfer]



SM5_A_3(3OMV)
RAF1_HUMAN
[Raw transfer]



SM5_B_4(3OMV)

[Raw transfer]



831_B_6(3II5)

[Raw transfer]



10Z_A_4(4H58)
BRAF_HUMAN
[Raw transfer]



FP3_B_4(3PRF)

[Raw transfer]



FP3_A_3(3PRF)
BRAF_HUMAN
[Raw transfer]



631_A_2(4JXF)
PLK4_HUMAN
[Raw transfer]



734_A_3(4E26)
BRAF_HUMAN
[Raw transfer]



ANP_A_7(3COK)
PLK4_HUMAN
[Raw transfer]
3 PsiBlast_PDB 86.3482% -80 - C1 -3FPQ 2.5 WNK1_RAT
25 PsiBlast_CBE 62.2333% -70 - C1 -3C4C 4.4
35 PsiBlast_CBE 62.0734% -60 - C1 -4E26 3.9 BRAF_HUMAN
53 PsiBlast_CBE 61.5734% -63 * C1 *4KSP 7.5 BRAF_HUMAN
16 PsiBlast_PDB 61.4834% -66 - C1 -3PPK 7.8 BRAF_HUMAN
55 PsiBlast_CBE 61.3034% -61 - C1 -5CT7 8.7 ?
9 PsiBlast_PDB 61.2933% -65 - C1 -4WO5 8.7 BRAF_HUMAN
69 PsiBlast_CBE 61.2533% -76 - C1 -3OMV 5.9
11 PsiBlast_PDB 61.0733% -65 - C1 -3C4C 7.0 BRAF_HUMAN
54 PsiBlast_CBE 60.9134% -60 - C1 -4FC0 8.2 BRAF_HUMAN
50 PsiBlast_CBE 60.8334% -66 - C1 -4H58 6.4 BRAF_HUMAN
65 PsiBlast_CBE 60.7134% -66 - C1 -4EHG 7.1
71 PsiBlast_CBE 60.6833% -68 - C1 -3OG7 8.5 BRAF_HUMAN
21 PsiBlast_CBE 60.4433% -68 - C1 -4WO5 7.2
51 PsiBlast_CBE 60.3434% -60 - C1 -4MBJ 6.4
52 PsiBlast_CBE 60.1734% -63 - C1 -4MBJ 4.3 BRAF_HUMAN
70 PsiBlast_CBE 60.1533% -72 - C1 -3OMV 3.7 RAF1_HUMAN
38 PsiBlast_CBE 59.9434% -59 - C1 -3TV4 7.2
17 PsiBlast_PDB 59.8434% -69 - C1 -3PRF 6.7 BRAF_HUMAN
56 PsiBlast_CBE 59.8334% -62 - C1 -5CT7 9.2 ?
20 PsiBlast_PDB 59.4734% -63 - C1 -3PSD 6.5 BRAF_HUMAN
41 PsiBlast_CBE 59.4434% -59 - C1 -3PSD 6.7
45 PsiBlast_CBE 59.4134% -57 - C1 -3PPK 7.1
31 PsiBlast_CBE 59.3134% -65 - C1 -4EHE 6.8 BRAF_HUMAN
59 PsiBlast_CBE 59.1433% -66 - C1 -4FK3 6.9 BRAF_HUMAN
29 PsiBlast_CBE 58.9734% -62 - C1 -4G9C 7.9 BRAF_HUMAN
22 PsiBlast_CBE 58.9633% -64 - C1 -4JVG 6.1
30 PsiBlast_CBE 58.9234% -62 - C1 -4EHE 7.4
14 PsiBlast_PDB 58.8834% -61 - C1 -3PSB 6.7 BRAF_HUMAN
47 PsiBlast_CBE 58.8434% -60 - C1 -3II5 8.5
66 PsiBlast_CBE 58.8134% -62 - C1 -4EHG 6.2 BRAF_HUMAN
23 PsiBlast_CBE 58.7933% -67 - C1 -4JVG 6.9 BRAF_HUMAN
33 PsiBlast_CBE 58.7634% -67 - C1 -4E4X 8.6 BRAF_HUMAN
39 PsiBlast_CBE 58.6634% -63 - C1 -3SKC 8.0
15 PsiBlast_PDB 58.4434% -61 - C1 -3PPJ 6.5 BRAF_HUMAN
13 PsiBlast_PDB 58.4334% -59 - C1 -3D4Q 6.6 BRAF_HUMAN
60 PsiBlast_CBE 58.4034% -64 - C1 -3IDP 9.7
10 PsiBlast_PDB 58.3233% -68 - C1 -4JVG 7.8 BRAF_HUMAN
44 PsiBlast_CBE 58.0334% -61 - C1 -3PRF 5.9
24 PsiBlast_CBE 58.0233% -67 - C1 -4JVG 7.2 BRAF_HUMAN
40 PsiBlast_CBE 58.0034% -64 - C1 -3SKC 7.3 BRAF_HUMAN
28 PsiBlast_CBE 57.8634% -64 - C1 -4G9C 8.2
67 PsiBlast_CBE 57.7634% -60 - C1 -1UWJ 7.2
58 PsiBlast_CBE 57.7234% -64 - C1 -1UWH 7.2 BRAF_HUMAN
42 PsiBlast_CBE 57.6234% -61 - C1 -3PSB 6.3
61 PsiBlast_CBE 57.4434% -57 - C1 -3IDP 9.5 BRAF_HUMAN
36 PsiBlast_CBE 57.4334% -58 - C1 -3TV6 7.8
37 PsiBlast_CBE 57.3134% -64 - C1 -3TV6 6.9 BRAF_HUMAN
48 PsiBlast_CBE 57.1334% -62 - C1 -3II5 9.4 BRAF_HUMAN
32 PsiBlast_CBE 57.1034% -63 - C1 -4E4X 8.1
62 PsiBlast_CBE 57.0134% -69 - C1 -5C9C 8.0 ?
46 PsiBlast_CBE 56.9634% -60 - C1 -3PPJ 6.3
57 PsiBlast_CBE 56.7034% -62 - C1 -1UWH 7.5
49 PsiBlast_CBE 56.6534% -59 - C1 -3D4Q 6.3
26 PsiBlast_CBE 56.6534% -58 - C1 -4PP7 7.9
43 PsiBlast_CBE 56.6234% -62 - C1 -3PRI 6.5
27 PsiBlast_CBE 56.6034% -63 - C1 -4PP7 7.5 BRAF_HUMAN
18 PsiBlast_PDB 56.5834% -63 - C1 -3PRI 6.7 BRAF_HUMAN
68 PsiBlast_CBE 56.5434% -63 - C1 -1UWJ 7.8 BRAF_HUMAN
72 PsiBlast_CBE 56.3134% -63 - C1 -4MNF 6.9
73 PsiBlast_CBE 55.7934% -61 - C1 -4MNF 5.7 BRAF_HUMAN
64 PsiBlast_CBE 55.2434% -59 - C1 -4G9R 7.9 BRAF_HUMAN
63 PsiBlast_CBE 53.1734% -55 - C1 -4G9R 8.5