Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCALKGFLEENFYTYSVAKGNHSTVYEFILLGLTDNAELQVTLFGIFLVVYLASFMGNFGLIMLIQISPQLHTPMYFFLSHLAFVDFSFTSSVAPNTLVNFLCEVKSITFYACAIQVCCFITFVVCELYLLSIMAYDRYVAICNPLLY-VILIPRKCIKLIASTYVYGFTVGL-----VQTVATSYLSFCDSNVINHFYHDDVPLVALACSDTHVKELMLLIIAGFNTLCSLVIVLISYGFIFFAILRIHSAEGRQKAFSTSASHLTSITIFYGTIIFMYPQPKSSHSLNMDKVASVFNVVVIPTLNPLIYSLRNQEVKNALKRIIEKLCLAVK 4IAQ Chain:A ((20-179)) ---------------------------------------KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQA------SECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDNWETLNDNLKVINAAQVKDALTKMRAAALDAQKATPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLLMAARERKAT

General information: TITO was launched using: RESULT: Template: 4IAQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -130161 for 944 contacts (-137.9/contact) + 2D Compatibility (PS) -14633 + (NN) 13 + (LL) 3496 1D Compatibility (HY) -8000 + (ID) 1800 Total energy: -151085.0 ( -160.05 by residue) QMean score : 0.211

(partial model without unconserved sides chains): PDB file : Tito_4IAQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IAQ-query.scw PDB file : Tito_Scwrl_4IAQ.pdb: