Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTNYWIGVVSEQHVLKGAAGGFAQLCHGKKAPLAKMKEGDWLIYYSPRDAYPDGKLLR-------SFTAIGKVKSGNIY-PYQMAPNFIPYRLDIDYYPCHKIGFYDIKSKLEFVQETKHLGF-LFRRGHFEISKKDFLTIAQAMGVNISGMAL 1WMM Chain:A ((2-144)) ---TYWICITNRENWEVIKRHNVWGVPKKHKNTLSRVKPGDKLVIYVRQEKDKEGNLLEPKIVGIYEVTSEPYVDFSRIFKP--GGKETYPYRVKIKPIKIGEINFKPLINDLKFIKNKKRWSMHFFGKAMRELPEEDYKLIEKLL---------

General information: TITO was launched using: RESULT: Template: 1WMM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 509 -61997 -121.80 -469.67 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -121.80 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.303

(partial model without unconserved sides chains): PDB file : Tito_1WMM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WMM-query.scw PDB file : Tito_Scwrl_1WMM.pdb: