Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTENFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEFTNS----------ESYCHPDGKDSVRGRLTFTEDEQPIVAHIWGDKPENFRKMSIGMAELGFKGLDINMGCPVPNVAGNGKGSGLICRPAV---AAELIQAAKAGGLPVSVKTRLGYTDVDEWREWLTHILKQDIANLSIHLRTRAEMSKVD-AHWELIPEIKKLRDEVAPDTLLTINGDIPDRQTGLKLAEQYGVDGIMIGRGIFTNPFAFEKEPKEHSSKELLDLLRLHLDLHDEYSKEEARPYKPLPRFFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFERKYLDGIE 3W9Z Chain:A ((3-242)) -------------VLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRIC-PELQNASR-----TPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGC-------------LLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGDIRQ-----RLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIP--------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3W9Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1147 -117996 -102.87 -584.14 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -102.87 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_3W9Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3W9Z-query.scw PDB file : Tito_Scwrl_3W9Z.pdb: