Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWNEFKAFAMRGNIVDLAIGVVIGGAFGKIVTSLVNDIIMPLVGLLLGGLDFSGLSFTFGDAVVKYGSFIQTIVNFLIISFSIFIVIRTLNGLRRKKEAEEEAAEEAVDAQEELLKEIRDLLKQQAKSPE 3HZQ Chain:A ((1-94)) MLKEFKEFALKGNVLDLAIAVVMGAAFNKIICSLVENIIMPLIGKIFGSVDFAKEWSFWG---IKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKE---------------------------------

General information: TITO was launched using: RESULT: Template: 3HZQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 137 -33105 -241.64 -352.18 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -241.64 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.064

(partial model without unconserved sides chains): PDB file : Tito_3HZQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HZQ-query.scw PDB file : Tito_Scwrl_3HZQ.pdb: