Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVL----SEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH 2VT4 Chain:A ((28-298)) -----------------------------------------------GNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQD-PGCCDFVT---NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIR---------------------EHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLA------------------

General information: TITO was launched using: RESULT: Template: 2VT4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -231865 for 1870 contacts (-124.0/contact) + 2D Compatibility (PS) -25178 + (NN) 321 + (LL) 4508 1D Compatibility (HY) -23600 + (ID) 4100 Total energy: -279914.0 ( -149.69 by residue) QMean score : 0.296

(partial model without unconserved sides chains): PDB file : Tito_2VT4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VT4-query.scw PDB file : Tito_Scwrl_2VT4.pdb: