Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCV---GGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 2Y00 Chain:A ((23-300)) ------------------------------------------LLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVS---FLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ------------SRV------MLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA----------------

General information: TITO was launched using: RESULT: Template: 2Y00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -248467 for 1936 contacts (-128.3/contact) + 2D Compatibility (PS) -26146 + (NN) -1166 + (LL) 5020 1D Compatibility (HY) -24800 + (ID) 4600 Total energy: -300159.0 ( -155.04 by residue) QMean score : 0.366

(partial model without unconserved sides chains): PDB file : Tito_2Y00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y00-query.scw PDB file : Tito_Scwrl_2Y00.pdb: