Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISTSEHSIFKNPAKNDGLRVRTIEVSEKFTSSAQNSDTIKKVVSQNNGHVLPIIAQFLLDNTNDVTSLFQKEDSVFYQLLSTESSNTGIRMIKHYATLTTTAHILNQSLDLQLNVSSIKNYLLSYHNETVSERSLADKAMDTIVQFIAENLGKFSQQTR------LANMIQNFGILSLKDDYIEVKIIRNVFDKMLTDSQFEDTKNVIDALDNAGKL--VSDRDRKTTKRNAKDDTGKSTSLVFYQIKIDLDYADVLGLQSQGRDNVIQKHSNPSQFKNTNLEEFMKSENTTLIVF 1CF5 Chain:A ((76-236)) --------------------------------------------------------------TRDVSYFFKESPPEAYNILFKGTRKITLPYTGNYENLQTAAHKIRENIDLGLPALSSAITTLFYYNAQS-----APSALLVLIQTTAE-AARFKYIERHVAKYVATNFKPNLAIISLENQWSALS--KQIF---LAQNQGGKFRNPVDLIKPTGQRFQVTNVDSDVVKGNIK---------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1CF5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 23600 for 1039 contacts (22.7/contact) + 2D Compatibility (PS) -15668 + (NN) 153 + (LL) 8364 1D Compatibility (HY) -6000 + (ID) 2050 Total energy: 8399.0 ( 8.08 by residue) QMean score : 0.111

(partial model without unconserved sides chains): PDB file : Tito_1CF5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CF5-query.scw PDB file : Tito_Scwrl_1CF5.pdb: