Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGILTFMDFCSGIGGGRLGLERCHLKCVGHAEINHEAIRTYELFFKDTHNFGDLMRINPNDLPNFDVLVSGFPCQAFSINGKRKGLEDERGTIIYGLIRILKVKQPKCFLLENVKGLIHHKQQETFKTIIKALQEAGYTTHYQILNSADFQLAQKRERLYIVGFRKDLK-RPFNFPLGLANDYCFKDFLDADNECYLDVSNATFQRYLRNPYNHNRVFLEDILTLENAVLDTRQSDLRLYFN--VFPTLRTSRHGLF-----YTQKGKIKRLNAVESLLLQGFPRDLIAKIKNNPNFKESHLLSQAGNAMSVNVIAAIAKQMLKAFNNE 2UYH Chain:A ((12-323)) ---LRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYEMNFGEKPE-GDITQVNEKTIPDHDILCAGFPCQAFSIQGKQKGFEDSRGTLFFDIARIVREKKPKVVFMENVKNFASHDNGNTLEVVKNTMNELDYSFHAKVLNALDYGIPQKRERIYMICFRNDLNIQNFQFPKPFELNTFVKDLLLPDSE----VEHLVIDRKDLVMTNQ-EIEQTTPKTVRLGIVGKGGSGERIYSTRGIAITLSAYGGGIFAKTGGYLVNGKTRKLHPRECARVMGYPDSY----KVHPSTSQAY--KQFGNSVVINVLQYIAYNIGSSLNFK

General information: TITO was launched using: RESULT: Template: 2UYH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -160420 for 2552 contacts (-62.9/contact) + 2D Compatibility (PS) -32350 + (NN) -11826 + (LL) 1508 1D Compatibility (HY) -22000 + (ID) 5250 Total energy: -230338.0 ( -90.26 by residue) QMean score : 0.421

(partial model without unconserved sides chains): PDB file : Tito_2UYH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2UYH-query.scw PDB file : Tito_Scwrl_2UYH.pdb: