Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNGNEPHGGVLINRCDPACHFEGCACQAELDQLALSDLELIAIGGYSPLTGFLGEKDYHSVVKEMRLANGLPWSLPITLPVGEKTARQLSAGDHVKLVKDGVTYGMITVTDIYQPDKTQEALSVFKTNDPAHPGVKKLLARPDYYIGGPITV-SSLPDKSFEQFYATPAETRAAFQKLGWKTIVGFQTRNPVHRAHEYIQKTALETVDGLLLHPLVGETKSDDIPSDIRMESYQALLNHYYPKDRVMLSVFPAAMRYAGPREAIFHALVRKNYGCTHFIVGRDHAGVGSYYGTYDAQNIFQSFTEEELGIKPLFFEHSFYCRKCGNMGTSKTCPHSPRD-HIHLSGTKVRELLRQGKKPPKEFSRPEVAAVLIKGLHQQPVAIKQNSGELQ 1V47 Chain:A ((17-349)) ------------------------------------DLENLATGAFFPVKGFMTREEALSVAHEMRLPTGEVWTIPILLQFREKP--RVGPGNTVALLHGGERVALLHVAEAYELDLEALARAVFGTDSETHPGVARLYGKGPYALAGRVEVLKPRPRTPLEK---TPEEVRAFFRQRGWRKVVAFQTRNAPHRAHEYLIRLGLELADGVLVHPILGAKKPDDFPTEVIVEAYQALIRDFLPQERVAFFGLATPMRYAGPKEAVFHALVRKNFGATHFLVGRDHAGVGDFYDPYAAHRIFDRLP--PLGIEIVKVGAVFHCPLCGGIASERTCPEGHREKRTAISMTKVRALLREGKAPPSELVRPELLPILRRGV---------------

General information: TITO was launched using: RESULT: Template: 1V47.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1794 -181845 -101.36 -549.38 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -101.36 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.569

(partial model without unconserved sides chains): PDB file : Tito_1V47.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V47-query.scw PDB file : Tito_Scwrl_1V47.pdb: