Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMNGIWLALNEEPDIPRNDIKLSYTHIAFTIEDHEFEEMSAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTGTLQDRLRYYKQEKTHMHFYDETAF 4JD1 Chain:A ((2-139)) -MLQGINHICFSVSNLEKSIEFYQKILQAKLLVKGRKLAYFDLNGLWIALNVEEDIPRNEIKQSYTHMAFTVTNEALDHLKEVLIQNDVNILPGRERDERDQRSLYFTDPDGHKFEFHTGTLQNRLEYYKEDKKHMTFY-----

General information: TITO was launched using: RESULT: Template: 4JD1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 478 -57856 -121.04 -419.24 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.90 3D Compatibility (PKB) : -121.04 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.644

(partial model without unconserved sides chains): PDB file : Tito_4JD1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JD1-query.scw PDB file : Tito_Scwrl_4JD1.pdb: