Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIFVDQDNYKEVSLKLTKKLLTSEHYQFLLCFKGEKLDITISVTPQSLVKLRDDINELIFMFSD 4ZUA Chain:A ((122-155)) --------------VKGLKELLVHEHPPMLACLKIEELLMLFAFSPQG-----------------

General information: TITO was launched using: RESULT: Template: 4ZUA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 35 -3431 -98.03 -100.91 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -98.03 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.159

(partial model without unconserved sides chains): PDB file : Tito_4ZUA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZUA-query.scw PDB file : Tito_Scwrl_4ZUA.pdb: