Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYAIIKTGGKQIKVEEGQTVYIEKLAAEAGETVTFEDVLFVGGDNVKVGNPTVEGATVTAKVEKQGRAKKITVFRYKPKKNVHKKQGHRQPYTKVTIEKINA 3J3V Chain:R ((1-102)) MYAIIKTGGKQIKVEEGQTVYIEKLAAEAGETVTFEDVLFVGGDNVKVGNPTVEGATVTAKVEKQGRAKKITVFRYKPKKNVHKKQGHRQPYTKVTIEKINA

General information: TITO was launched using: RESULT: Template: 3J3V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain R - contact count / total energy / energy per contact / energy per residue : 389 -26713 -68.67 -261.89 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain R : 1.00 3D Compatibility (PKB) : -68.67 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 1.00 QMean score : 0.321

(partial model without unconserved sides chains): PDB file : Tito_3J3V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3J3V-query.scw PDB file : Tito_Scwrl_3J3V.pdb: