Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKQLIQSEEEFKRIAEQEGVFVFLKHSTTCPISQAAFHEFDAFANQHEDVPAYYLQVQEARPLSNFIAETYGVKHESPQIFIIQNGEVKWHTSHSQITEAAIEQHLS 3IV4 Chain:A ((5-103)) -----LSSIDQFEQVIEENKYVFVLKHSETCPISANAYDQFNKFLYER-D-DGYYLIVQQERDLSDYIAKKTNVKHESPQAFYFVNGE-VWNRDHGDINVSSLAQ---

General information: TITO was launched using: RESULT: Template: 3IV4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 422 -20261 -48.01 -208.87 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -48.01 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.391

(partial model without unconserved sides chains): PDB file : Tito_3IV4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IV4-query.scw PDB file : Tito_Scwrl_3IV4.pdb: