Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDIKEAGPFPVKKEQFRMTVNGQAWEVAAVPTTHLSDLLRKEFQLTGTKVSCGIGRCGACSILIDGKLANACMTMAYQADGHSITTIEGLQKE-ELDMCQTAFLEEGGFQCGYCTPGMIIALKALFRETPQPSDKDIEEGLAGNLCRCTGYGGIMRSACRIRRELNGGRRESGF 4ZOH Chain:C ((8-152)) -----------QKVKITLKINGEKYETEVEPRRLLVHVLR-ELGFTGVHIGCDTSNCGACTVIMNGKSVKSCTVLAVEADGAEILTVEGLAKDGKLHPIQEAFWENHALQCGYCTPGMIMEAYWLLREKPNPTEEEIREGISGNLCRCTGYQNIVKA-----------------

General information: TITO was launched using: RESULT: Template: 4ZOH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 700 -82573 -117.96 -573.42 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain C : 0.82 3D Compatibility (PKB) : -117.96 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.520

(partial model without unconserved sides chains): PDB file : Tito_4ZOH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZOH-query.scw PDB file : Tito_Scwrl_4ZOH.pdb: