Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKELQEHELDHI---EDDVYLLYLYTPFCGTCQLASKMLT-VVKEMLPDVAFYQNNVNYSPTFAKAYQIESVPCFLLFKGGKMVERGYAFHSVSYLYELIKQKSSSASHL 3ZIV Chain:A ((4-103)) --EINDENFDEVIKKSDKVVVVDFWAEWCGPCRMIAPIIEELAEEYAGKVVFGKVNVDENPEIAAKYGIMSIPTLLFFKNGKVVDQLVGARPKEALKERIKK--------

General information: TITO was launched using: RESULT: Template: 3ZIV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 377 -21596 -57.28 -224.95 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -57.28 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.621

(partial model without unconserved sides chains): PDB file : Tito_3ZIV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ZIV-query.scw PDB file : Tito_Scwrl_3ZIV.pdb: