Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKYEVMYIIRPNIDEESKKAVIERFNNVLTSNGAEITGTKDWGKRRLAYEINDFRDGFYQIVNVQSDAAAVQEFDRLAKISDDIIRHIVVKEEE 3R3T Chain:A ((5-97)) -RKYEIMYIIRPGVEEEAQKALVERFAGVLTNNGAEIINTKEWGKRRLAYEINDLREGFYMILNVNANAEAINEFDRLAKINEDILRHIVVKEE-

General information: TITO was launched using: RESULT: Template: 3R3T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 111 -18615 -167.70 -200.16 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.94 3D Compatibility (PKB) : -167.70 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.94 QMean score : 0.395

(partial model without unconserved sides chains): PDB file : Tito_3R3T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3R3T-query.scw PDB file : Tito_Scwrl_3R3T.pdb: