Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQW-ERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTI-AVASHPGVSNTEVVRNMPRPLVAVAAILAPLMQDAELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG 3RD5 Chain:A ((4-291)) -TGWTAADLPSFAQRTVVITGANSGLGAVTARELARRGATVIMAVRDTRKG-EAAAR----TMAGQVEVRELDLQDLSSVRRFADGVSG----ADVLINNAGIMAVPYALTVDGFESQIGTNHLGHFALTNLLLPRLT----DRVVTVSSMAH-WPGRINLEDLNWRSRRYSPWLAYSQSKLANLLFTSELQRRLTAAGSPLRALAAHPGYSHTNL------------------ATDADFGARQTLYAASQD-LPGDSFVGPR-FGYL-GRTQPVGRSRRAKDAGMAAALWALSEQLTKTEFPL-

General information: TITO was launched using: RESULT: Template: 3RD5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -124513 for 2409 contacts (-51.7/contact) + 2D Compatibility (PS) -29446 + (NN) -16842 + (LL) 2780 1D Compatibility (HY) -22000 + (ID) 7000 Total energy: -197021.0 ( -81.79 by residue) QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_3RD5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3RD5-query.scw PDB file : Tito_Scwrl_3RD5.pdb: