Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAEIDYKKVTGMIHSTESFGSVDGPGIRFIIFMQGCKMRCQYCHNPDTWEMETNNSKERTVEDVLKEALRYKHFWGKDGGITVSGGEAMLQIDFITALFIEAKKLGIHTTLDTCGFAYRATPEYHAILEKLLDVTDLVLLDLKEIDPEQHKIVTRQSNKNILQFARYLSDRGTPVWIRHVLVPGLTDIDDHLKRLGEFVQTLD-NVDKFEVLPYHTMGEFKWRELGIPYPLAG-VKPPTPERVKNAKDIMKTESYTEYLKRIQN 3CAN Chain:A ((7-185)) -----------------------------------------------------------------------------GGGVTFCGGEPLLHPEFLIDILKRCGQQGIHRAVDTTLL-ARK-----ETVDEVMRNCELLLIDLKSMDSTVHQTFCDVPNELILKNIRRVAEADFPYYIRIPLIEGVNADEKNIKLSAEFLASLPRHPEIINLLPYHD-----------------KMQTPSEEVQQQCIQILTDYGLKATIGG---

General information: TITO was launched using: RESULT: Template: 3CAN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -23095 for 1147 contacts (-20.1/contact) + 2D Compatibility (PS) -16173 + (NN) 3080 + (LL) 6492 1D Compatibility (HY) 1600 + (ID) 950 Total energy: -29046.0 ( -25.32 by residue) QMean score : 0.318

(partial model without unconserved sides chains): PDB file : Tito_3CAN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CAN-query.scw PDB file : Tito_Scwrl_3CAN.pdb: