Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNINVDVKQNENDIQVNIAGEIDVYSAPVLREKLVPLAEQGADLRICLKDVSYMDSTGLGVFVGTFKMVKKQGGSLKLENLSERLIRLFDITGLKDIIDISAKSEGGVQ 4HYL Chain:A ((17-104)) ---------------ITLHGHLDTRSSPAVQAAVLPRVTAKGKMILDLREVSYMSSAGLRVLLSLYRHTSNQQGALVLVGVSEEIRDTMEITGFWNFFTACAS------

General information: TITO was launched using: RESULT: Template: 4HYL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 340 -77167 -226.96 -876.89 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -226.96 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.681

(partial model without unconserved sides chains): PDB file : Tito_4HYL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HYL-query.scw PDB file : Tito_Scwrl_4HYL.pdb: