Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQPSKTTKLTKDEVDRLISDYQTKQDEQAQETLVRVYTNLVDMLAKKYS-KGKSFHEDLRQVGMIGLLGAIKRYDPVVGKSFEAFAIPTIIGEIKRFLRDKTWSVHVPRRIKELGPRIKMAVDQLTTETQRSPKVEEIAEFLDVSEEEVLETMEMGKSYQALSVDHSIEADSDGSTVTILDIVGSQEDGY--------------ERVNQQLM---LQSVLHVLSDREKQIIDL--TYIQNKSQ--KETGDILGISQMHVSRLQRKAVKKLREALIEDPSMELM 4XLP Chain:F ((101-333)) -----------------------AREGEAARQHLIEANLRLVVSIAKKYTGRGLSFL-DLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAE-------------AMGPGWDAKRVEETLKIAQE--PVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLK------------

General information: TITO was launched using: RESULT: Template: 4XLP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 552 -64425 -116.71 -305.33 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain F : 0.72 3D Compatibility (PKB) : -116.71 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.460

(partial model without unconserved sides chains): PDB file : Tito_4XLP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XLP-query.scw PDB file : Tito_Scwrl_4XLP.pdb: