Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVTYWTGENLTLRAIQPEDIVIFDSLDDEILRNMDSLHFPRSA--NNMREWVEEQLEKDEFRFIAVESDNNIVGMIETFDCDRKN----GTFGYYLAVFEPYRGKGFAKEMILMVLRFFFLELAYQKVNTTVYSFNNPSIRLHEKLGFMKEGQLRKIIFTKGAYYDGICFGMTREEFELNHG 2GE3 Chain:A ((6-162)) --------DTVTIKPIRAEHVESFHRALDAVSRERKYLSFLEAPPLEAVRAFVLDMIENDHPQFVAI-ADGDVIGWCDIRRQDRATRAHCGTLGM--GILPAYRNKGLGARLMRRTLDAAH-EFGLHRIELSVHADNARAIALYEKIGFAHEGRARDAVSIDGHYIDSL--------------

General information: TITO was launched using: RESULT: Template: 2GE3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 584 -3615 -6.19 -23.94 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -6.19 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_2GE3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GE3-query.scw PDB file : Tito_Scwrl_2GE3.pdb: