Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSSGSSHPFLLTGFPGLEEAHHWISVFFLFMYISILFGNGTLLLLIKEDHNLHEPMYFFLAMLAATDLGLALTTMPTVLGVLWLDHREIGSAA----CFSQAYFIHSLSFLESGILLAMAYDRFIAICNPLRYTSVLTNTR---------VVKIGLGVL-MRGFVSVVPPIRPLYFFLYCHSHVLSHAFCLHQDVIKLACADTTFNRLYPAVLVVFIFVLD-YLIIFISYVLILKTVLSIASREERAKALITCVSHICCVLVFYVTVIGLS-----LIHRFGKQVPHIVHLIMSYAYFLF-----PPLMNPITYSVKTKQIQNAILHLFTTHRIGT 4UG2 Chain:A ((21-306)) ------------------------------------ILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIAI------STGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVA---CLFEDVVPM--NYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQL------------ARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLR-

General information: TITO was launched using: RESULT: Template: 4UG2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -222389 for 1801 contacts (-123.5/contact) + 2D Compatibility (PS) -24693 + (NN) -5540 + (LL) 4756 1D Compatibility (HY) -20400 + (ID) 3200 Total energy: -271466.0 ( -150.73 by residue) QMean score : 0.229

(partial model without unconserved sides chains): PDB file : Tito_4UG2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UG2-query.scw PDB file : Tito_Scwrl_4UG2.pdb: