Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAGRMSTSNHTQFHPSSFLLLGIPGLEDVHIWIGVPFFFVYLVALLGNTALLFVIQTEQSLHEPMYYFLAMLDSIDLGLSTATIPKMLGIFWFNTKEISFGGCLSHMFFIHFFTAMESIVLVAMAFDRYIAICKPLRYTMILT-SKIISLIAGIAVLRSLYMVVPLVFLLLRLPFCGHRIIPHTYCEHMGIARLAC---ASIKVNIRFGLGNISLLLLDVILIILSYVRILYAVF---CLPSWEAR--LKALNTCGSHIGVILAFFTPAF--------FSFLTHRFGHNIP---QYIHIILANLYVVVPPALNPVIYGVRTKQIRERVLRIFLKTNH 4UG2 Chain:A ((16-302)) ---------------------------------------IAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIAIS--TGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTP----MLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQL------ARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSH-APLWLMYLAIVLSHTNSVV----NPFIYAYRIREFRQTFRKIIRSHVL

General information: TITO was launched using: RESULT: Template: 4UG2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -269245 for 1970 contacts (-136.7/contact) + 2D Compatibility (PS) -25720 + (NN) -4067 + (LL) 3508 1D Compatibility (HY) -24800 + (ID) 3500 Total energy: -323824.0 ( -164.38 by residue) QMean score : 0.230

(partial model without unconserved sides chains): PDB file : Tito_4UG2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UG2-query.scw PDB file : Tito_Scwrl_4UG2.pdb: