Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPGKQSEEGPAEAGASEDSEEEGLGGLTLEELQQGQEAARALEDMMTLSAQTLVRAEVDELYEEVRPLGQGCYGRVLLVTHRQKGTPLALKQLPKPRTSL--RGFLYEFCVGLSLGAHSAIVTAYGIGIESAHSYSFLTEPVLHGDLMAFIQPKVGLPQPAVHRCAAQLASALEYIHARGLVYRDLKPENVLVCDPACRRFKLTDFG-----HTRPRGTLLRLAGPPIPYTAPELCAPPPLPEGLPIQPALDAWALGVLLFCLLTGYFPWDRPLAEADPFYEDFLIWQASGQPRDRPQPWFGLAAAADALLRGLLDPHPRRRSAVIAIREHLGRPWRQREGEAEAVGAVEEEAGQ 2HXQ Chain:A ((6-260)) -----------------------------------------------------------EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKR---CPENIKKEICINKMLN-HENVVKFYGHRREGNIQYLFL-EYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERD--NLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK----RREFHAEP-VDVWSCGIVLTAMLAGELPWDQP-SDSCQEYSD---WK---EKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRP----------

General information: TITO was launched using: RESULT: Template: 2HXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -139591 for 1855 contacts (-75.3/contact) + 2D Compatibility (PS) -25962 + (NN) -19008 + (LL) 5508 1D Compatibility (HY) -17200 + (ID) 4100 Total energy: -200353.0 ( -108.01 by residue) QMean score : 0.336

(partial model without unconserved sides chains): PDB file : Tito_2HXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HXQ-query.scw PDB file : Tito_Scwrl_2HXQ.pdb: