Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEWQDLAQLPVSIFKDYVTDAQDAEKPFIWTEVFLREINRSNQEIILHIWPMTKTVILGMLDRELPHLELAKKEIISRGYEPVVRNFGGLAVVADEGILNFSLIIPDVFERKLSISDGYLIMVDFIRSIFSDFYQPIEHFEVETSYCP--GKFDLSINGKKFAGLAQRRIKNGIAVSIYLSVCGDQKERSRMISDFYKIGLGDTGSPIAYPNVDPEIMANLSDLLDCPMTVEDVIDRMLISLKQ-VGFNDRLLMIRPDLVAEFDRFQAKSMANKGTVSRDE 2C8M Chain:A ((1-251)) -------MEGRLLLLET---PGNTRMSLAYDEAIYRSFQYG-DKPILRFYRHDRSVIIGYFQ--VAEEEVDLDYMKKNGIMLARRYTGGGAVYHDLGDLNFSVVRSSDD---MDITSMFRTMNEAVVNSLRILGLDARPGELNDVSIPVNKKTDIMAGEKKIMGAAGAMRKGAKLWHAAMLVHTDLDMLSAVLK---------------------ERVANVTDFV--DVSIDEVRNALIRGFSETLHIDFREDTITEKEESLARELFDKKYSTEEWNMGL-

General information: TITO was launched using: RESULT: Template: 2C8M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -175165 for 1921 contacts (-91.2/contact) + 2D Compatibility (PS) -24739 + (NN) -1627 + (LL) 1504 1D Compatibility (HY) -5600 + (ID) 2100 Total energy: -207727.0 ( -108.13 by residue) QMean score : 0.394

(partial model without unconserved sides chains): PDB file : Tito_2C8M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C8M-query.scw PDB file : Tito_Scwrl_2C8M.pdb: