Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKQYRVLLYYKYVPIEDPEAFREQHLAFCKELGLLGRILVSSEGINGTVSGTVEQTEKYMETMKADPRFADMVFKIDEAEGHAFKKIFVRHKKELVTLRLEDDVDPNETTGQHLKPAEFYEKMQDPNTIVIDARNDYEYDLGHFRGAV----RPDIEAFRELPEWIEEHKDMLE---GKKILTYCTGGVRCEKFSGWLVKQGFEDVAQLDGGI---VTYGKDPEVQGKLWDGQCYVFDERISVPVNRVEHVIVGKDYFTGEPCERYVNCANPSCNKKMICTPENEYKYMRSCSHECRTNPRNLYVKEHNMTEEEVNARLAAIETEDHAAAE 3D1P Chain:A ((37-135)) ----------------------------------------------------------------------------------------------------------------------------HDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSHGGD-------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3D1P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 335 -29539 -88.18 -331.90 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -88.18 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.592

(partial model without unconserved sides chains): PDB file : Tito_3D1P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3D1P-query.scw PDB file : Tito_Scwrl_3D1P.pdb: