Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIQLSKGQRIDLTKTNPGLTKAVIGLGWDTNKYSGGHDFDLDASAFLVDAHDNCVNDLDFVFYNNLEHPSGGVIHTGDNRTGEGDGDDEQIIVDFSKIPAHIEKIGITVTIHDAEARSQNFGQVSNAFVRVVDEETQNELLRFDLGEDFSIETAVVVCELYRH-GGEWKFNAIGSGFSGGLAALCRNYGLQV 2QZ7 Chain:A ((22-190)) ------------------GLKRVDVRLKWDPSPW-DRPPHHLDIIATTYAADAPHGRPVYVVQFD-KRSPDGTINMSRHSRTGQGFGFVEEMTFELDRLSPSIARVIVGVAIHQDN-GHKTFDDVSNTGVVVAEG--YRELLTDGFE-RVAGATAATVAEFTRNASGAWEFREAVRGFDSDPVLFATEMGSAP

General information: TITO was launched using: RESULT: Template: 2QZ7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 927 -102669 -110.75 -611.12 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -110.75 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_2QZ7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QZ7-query.scw PDB file : Tito_Scwrl_2QZ7.pdb: