Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAG--IGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQEVHS 1L1R Chain:A ((35-179)) -------------------------------PAALDAVRKEVTAHYKDVPITKVVGIESRGFILGGIVANSLGVGFVALRKAGKLP---GDVCKCTFDMEYQKGVTIEVQKRQLGPHDVVLLHDDVLATGGTLLAAIELCETAGVKPENIYINVLYEIEALKGREKVGQKCTRLFSVIR-----------------

General information: TITO was launched using: RESULT: Template: 1L1R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 752 -96709 -128.60 -676.29 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -128.60 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.482

(partial model without unconserved sides chains): PDB file : Tito_1L1R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L1R-query.scw PDB file : Tito_Scwrl_1L1R.pdb: