Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLAILTMSGFLEARPRVGYFYTGKTGTQLLADKLKKLQVKDFQSIPVVIHENVSVYDAICTMFLEDVGTLFVVDRDAVLVGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRREDYVMDIAKHLIEKQIDALPVIKDTDKGFEVIGRVTKTNMTKILVSLSENEIL 3KH5 Chain:A ((95-205)) ---------------------------------------------------------------------------------------ITLKENADIDEAIETFLTKNVGGAPIVNDENQLISLITERDVIRALLDKIDENEV-IDDYITR--DVIVATPGERLKDVARTMVRNGFRRLPVVSEG----RLVGIITSTDFIKLLGS-------

General information: TITO was launched using: RESULT: Template: 3KH5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 262 -47056 -179.60 -423.92 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -179.60 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.482

(partial model without unconserved sides chains): PDB file : Tito_3KH5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KH5-query.scw PDB file : Tito_Scwrl_3KH5.pdb: