Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDLKQYVTIVPDYPKEGVQFKDITTLMDKGDVYRYATDQIVEYAKEK---QIDLVVGPEARGFIIGCPVAYALGVGFAPVRKEGKLPREVIKVDYGLEYGKDVLTIHKDAIKPGQRVLITDDLLATGGTIEATIKLVEELGGVVAGIAFLIELSYLDGRNKLEDYDILTLMKY 4X45 Chain:A ((9-179)) --VEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPGFSLLQY

General information: TITO was launched using: RESULT: Template: 4X45.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 850 -34961 -41.13 -208.10 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -41.13 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.516

(partial model without unconserved sides chains): PDB file : Tito_4X45.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4X45-query.scw PDB file : Tito_Scwrl_4X45.pdb: