Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNVAIVGDGGHGKVIRELINARSDTRLAAVLDDKFKTFEGGKEWYTGPPKAVTELRRLIPDVLFLIAVGNNSVRKQLAERLGLGKDDFITLIHPSAIVSKSAVIGE--GTVIMAGAIIQADARIGAHCIINTGAVAEHDNQISDYVHLSPRATLSGAVSVQEGAHVGTGASVIPQIIIGAWSIVGAGSAVIRSIPDRVTAAGAPARIISSIQTSNKG 2NPO Chain:A ((5-193)) -EKIYIYG--GHGLVCEDV--AKNMGYKECIFLDDFKGMK---------------FESTLPKYDFFIAIGNNEIRKKIYQKISENGFKIVNLIHKSALISPSAIVEENAGILIMPYVVINAKAKIEKGVILNTSSVIEHECVIGEFSHVSVGAKCAGNVKIGKNCFLGINSCVLPNLSLADDSILGGGATLVKNQDEKGVFVGVPAK-----------

General information: TITO was launched using: RESULT: Template: 2NPO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1100 -106364 -96.69 -574.94 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -96.69 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.548

(partial model without unconserved sides chains): PDB file : Tito_2NPO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2NPO-query.scw PDB file : Tito_Scwrl_2NPO.pdb: